Flights from Chicago to Eastern South Dakota

Cheapest flights from Chicago

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$189 Roundtrip, found 1 day ago

$189

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $189 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$219 Roundtrip, found 1 day ago

$219

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $219 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$225 Roundtrip, found 1 day ago

$225

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $225 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$245 Roundtrip, found 1 day ago

$245

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $245 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$249 Roundtrip, found 1 day ago

$249

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $249 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$254 Roundtrip, found 1 day ago

$254

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $254 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$272 Roundtrip, found 1 day ago

$272

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $272 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$278 Roundtrip, found 1 day ago

$278

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $278 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$279 Roundtrip, found 1 day ago

$279

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $279 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$285 Roundtrip, found 1 day ago

$285

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $285 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$294 Roundtrip, found 1 day ago

$294

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $294 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$302 Roundtrip, found 1 day ago

$302

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $302 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$304 Roundtrip, found 1 day ago

$304

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $304 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$305 Roundtrip, found 1 day ago

$305

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $305 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$307 Roundtrip, found 1 day ago

$307

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $307 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$310 Roundtrip, found 1 day ago

$310

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $310 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$314 Roundtrip, found 1 day ago

$314

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $314 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$319 Roundtrip, found 1 day ago

$319

Roundtrip

found 1 day ago

Select United flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $319 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$376 Roundtrip, found 1 day ago

$376

Roundtrip

found 1 day ago

Select American Airlines flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $376 found 1 day ago

Fri, Jul 11 - Mon, Jul 14

ORD

O'Hare Intl.

FSD

Sioux Falls Regional

$424 Roundtrip, found 1 day ago

$424

Roundtrip

found 1 day ago

Select Delta flight, departing Fri, Jul 11 from O'Hare Intl. to Sioux Falls Regional, returning Mon, Jul 14, priced at $424 found 1 day ago