Flights from Chicago to Des Moines

Cheapest flights from Chicago

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 19 - Tue, Jul 22

MDW

Midway Intl.

DSM

Des Moines Intl.

$209 Roundtrip, found 1 day ago

$209

Roundtrip

found 1 day ago

Select Delta flight, departing Sat, Jul 19 from Midway Intl. to Des Moines Intl., returning Tue, Jul 22, priced at $209 found 1 day ago

Tue, Jul 15 - Sat, Jul 19

MDW

Midway Intl.

DSM

Des Moines Intl.

$264 Roundtrip, found 1 day ago

$264

Roundtrip

found 1 day ago

Select Delta flight, departing Tue, Jul 15 from Midway Intl. to Des Moines Intl., returning Sat, Jul 19, priced at $264 found 1 day ago

Sat, Jul 19 - Wed, Jul 23

MDW

Midway Intl.

DSM

Des Moines Intl.

$316 Roundtrip, found 1 day ago

$316

Roundtrip

found 1 day ago

Select Delta flight, departing Sat, Jul 19 from Midway Intl. to Des Moines Intl., returning Wed, Jul 23, priced at $316 found 1 day ago

Tue, Jul 15 - Thu, Jul 24

MDW

Midway Intl.

DSM

Des Moines Intl.

$319 Roundtrip, found 1 day ago

$319

Roundtrip

found 1 day ago

Select Delta flight, departing Tue, Jul 15 from Midway Intl. to Des Moines Intl., returning Thu, Jul 24, priced at $319 found 1 day ago

Sat, Jul 19 - Sun, Jul 20

MDW

Midway Intl.

DSM

Des Moines Intl.

$324 Roundtrip, found 1 day ago

$324

Roundtrip

found 1 day ago

Select Delta flight, departing Sat, Jul 19 from Midway Intl. to Des Moines Intl., returning Sun, Jul 20, priced at $324 found 1 day ago

Tue, Jul 15 - Wed, Jul 23

MDW

Midway Intl.

DSM

Des Moines Intl.

$371 Roundtrip, found 1 day ago

$371

Roundtrip

found 1 day ago

Select Delta flight, departing Tue, Jul 15 from Midway Intl. to Des Moines Intl., returning Wed, Jul 23, priced at $371 found 1 day ago

Fri, Jul 18 - Sat, Jul 19

MDW

Midway Intl.

DSM

Des Moines Intl.

$374 Roundtrip, found 1 day ago

$374

Roundtrip

found 1 day ago

Select Delta flight, departing Fri, Jul 18 from Midway Intl. to Des Moines Intl., returning Sat, Jul 19, priced at $374 found 1 day ago

Tue, Jul 15 - Fri, Jul 18

MDW

Midway Intl.

DSM

Des Moines Intl.

$378 Roundtrip, found 1 day ago

$378

Roundtrip

found 1 day ago

Select Delta flight, departing Tue, Jul 15 from Midway Intl. to Des Moines Intl., returning Fri, Jul 18, priced at $378 found 1 day ago

Fri, Jul 18 - Thu, Jul 24

MDW

Midway Intl.

DSM

Des Moines Intl.

$429 Roundtrip, found 1 day ago

$429

Roundtrip

found 1 day ago

Select Delta flight, departing Fri, Jul 18 from Midway Intl. to Des Moines Intl., returning Thu, Jul 24, priced at $429 found 1 day ago

Mon, Jul 21 - Tue, Jul 22

MDW

Midway Intl.

DSM

Des Moines Intl.

$447 Roundtrip, found 1 day ago

$447

Roundtrip

found 1 day ago

Select Delta flight, departing Mon, Jul 21 from Midway Intl. to Des Moines Intl., returning Tue, Jul 22, priced at $447 found 1 day ago

Fri, Jul 18 - Wed, Jul 23

MDW

Midway Intl.

DSM

Des Moines Intl.

$481 Roundtrip, found 1 day ago

$481

Roundtrip

found 1 day ago

Select Delta flight, departing Fri, Jul 18 from Midway Intl. to Des Moines Intl., returning Wed, Jul 23, priced at $481 found 1 day ago

Fri, Jul 18 - Sun, Jul 20

MDW

Midway Intl.

DSM

Des Moines Intl.

$489 Roundtrip, found 1 day ago

$489

Roundtrip

found 1 day ago

Select Delta flight, departing Fri, Jul 18 from Midway Intl. to Des Moines Intl., returning Sun, Jul 20, priced at $489 found 1 day ago

Sun, Jul 20 - Tue, Jul 22

MDW

Midway Intl.

DSM

Des Moines Intl.

$574 Roundtrip, found 1 day ago

$574

Roundtrip

found 1 day ago

Select Delta flight, departing Sun, Jul 20 from Midway Intl. to Des Moines Intl., returning Tue, Jul 22, priced at $574 found 1 day ago

Mon, Jul 21 - Mon, Jul 21

MDW

Midway Intl.

DSM

Des Moines Intl.

$651 Roundtrip, found 1 day ago

$651

Roundtrip

found 1 day ago

Select Delta flight, departing Mon, Jul 21 from Midway Intl. to Des Moines Intl., returning Mon, Jul 21, priced at $651 found 1 day ago

Sun, Jul 20 - Mon, Jul 21

MDW

Midway Intl.

DSM

Des Moines Intl.

$681 Roundtrip, found 1 day ago

$681

Roundtrip

found 1 day ago

Select Delta flight, departing Sun, Jul 20 from Midway Intl. to Des Moines Intl., returning Mon, Jul 21, priced at $681 found 1 day ago

Fri, Jul 18 - Fri, Jul 18

MDW

Midway Intl.

DSM

Des Moines Intl.

$772 Roundtrip, found 1 day ago

$772

Roundtrip

found 1 day ago

Select Delta flight, departing Fri, Jul 18 from Midway Intl. to Des Moines Intl., returning Fri, Jul 18, priced at $772 found 1 day ago