
$150 Cheap American Airlines flights Portland (PDX) to Des Moines (DSM)
Prices were available within the past 7 days and start at $150 for one-way flights and $437 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jul 6 - Mon, Jul 7
PDX
Portland
DSM
Des Moines
$437 Roundtrip, found 16 hours ago
$437
Roundtrip
found 16 hours ago

Sun, Jul 6 - Mon, Jul 7
PDX
Portland
DSM
Des Moines
$487 Roundtrip, found 16 hours ago
$487
Roundtrip
found 16 hours ago

Sun, Jul 6 - Mon, Jul 7
PDX
Portland
DSM
Des Moines
$517 Roundtrip, found 16 hours ago
$517
Roundtrip
found 16 hours ago

Sun, Jul 6 - Mon, Jul 7
PDX
Portland
DSM
Des Moines
$530 Roundtrip, found 16 hours ago
$530
Roundtrip
found 16 hours ago

Sun, Jul 6 - Mon, Jul 7
PDX
Portland
DSM
Des Moines
$541 Roundtrip, found 16 hours ago
$541
Roundtrip
found 16 hours ago

Sun, Jul 6 - Mon, Jul 7
PDX
Portland
DSM
Des Moines
$580 Roundtrip, found 16 hours ago
$580
Roundtrip
found 16 hours ago
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Most Popular American Airlines Routes from Portland
Most Popular American Airlines Routes from Des Moines
- Jacksonville to Sioux Falls (JAX - FSD)
- Knoxville to Orange County (TYS - SNA)
- Columbia to Fort Myers (COU - RSW)
- Orlando to Bogotá (MCO - BOG)
- Cedar Rapids to Fort Lauderdale (CID - FLL)
- Pittsburgh to Wilmington (PIT - ILM)
- Houston to Kahului (IAH - OGG)
- New York to Fresno (JFK - FAT)
- Little Rock to Seattle (LIT - SEA)
- Fort Lauderdale to Atlanta (FLL - ATL)
Popular Domestic Routes in Des Moines Intl.
- Houston to Kahului (IAH - OGG)
- Little Rock to Seattle (LIT - SEA)
- Orlando to Bogotá (MCO - BOG)
- Fort Lauderdale to Atlanta (FLL - ATL)
- New York to Punta Cana (JFK - PUJ)
- New York to Fresno (JFK - FAT)
- Pittsburgh to Wilmington (PIT - ILM)
- Greensboro to Denver (GSO - DEN)
- Jacksonville to Sioux Falls (JAX - FSD)
- Pittsburgh to Atlanta (PIT - ATL)