$139 Cheap American Airlines flights New Orleans (MSY) to Knoxville (TYS)

View $139 flight on Sat, Jan 31, 2026Opens in a new window

$139 Cheap American Airlines flights New Orleans (MSY) to Knoxville (TYS)

Prices were available within the past 7 days and start at $139 for one-way flights and $279 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Feb 11 - Wed, Feb 18
MSY
New Orleans
TYS
Knoxville
$279 Roundtrip, found 6 hours ago
$279
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Feb 11 from New Orleans to Knoxville, returning Wed, Feb 18, priced at $279 found 6 hours ago
American Airlines
Tue, Feb 10 - Wed, Feb 18
MSY
New Orleans
TYS
Knoxville
$332 Roundtrip, found 2 days ago
$332
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Feb 10 from New Orleans to Knoxville, returning Wed, Feb 18, priced at $332 found 2 days ago

Find the cheapest month to fly from New Orleans (MSY) to Knoxville (TYS)

April is typically the cheapest month to fly

From $198 - $419 per traveler.

Travel information

Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, Frontier Airlines, United
Popular airline
Frontier Airlines
Distance
867 km

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