$153 Cheap American Airlines flights Des Moines (DSM) to Fort Myers (RSW)

View $153 flight on Tue, Mar 10, 2026Opens in a new window

$153 Cheap American Airlines flights Des Moines (DSM) to Fort Myers (RSW)

Prices were available within the past 7 days and start at $153 for one-way flights and $305 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
RSW
Fort Myers
$305 Roundtrip, found 1 day ago
$305
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 10 from Des Moines to Fort Myers, returning Tue, Mar 17, priced at $305 found 1 day ago
American Airlines
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
RSW
Fort Myers
$328 Roundtrip, found 1 day ago
$328
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 10 from Des Moines to Fort Myers, returning Tue, Mar 17, priced at $328 found 1 day ago
American Airlines
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
RSW
Fort Myers
$345 Roundtrip, found 1 day ago
$345
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 10 from Des Moines to Fort Myers, returning Tue, Mar 17, priced at $345 found 1 day ago
American Airlines
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
RSW
Fort Myers
$355 Roundtrip, found 1 day ago
$355
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 10 from Des Moines to Fort Myers, returning Tue, Mar 17, priced at $355 found 1 day ago
American Airlines
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
RSW
Fort Myers
$379 Roundtrip, found 1 day ago
$379
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 10 from Des Moines to Fort Myers, returning Tue, Mar 17, priced at $379 found 1 day ago
American Airlines
Tue, Mar 10 - Tue, Mar 17
DSM
Des Moines
RSW
Fort Myers
$391 Roundtrip, found 1 day ago
$391
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Mar 10 from Des Moines to Fort Myers, returning Tue, Mar 17, priced at $391 found 1 day ago

Find the cheapest month to fly from Des Moines (DSM) to Fort Myers (RSW)

August is typically the cheapest month to fly

From $191 - $680 per traveler.

Alternative airports near Fort Myers

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Southwest Florida Intl. RSW. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $368
RSW
Southwest Florida Intl.
Cheapest
Average driving time to city center22 min
Flights from $368
Flights from Des Moines (DSM) to Fort Myers (RSW)
Origin airport
Des Moines Intl.
Destination airport
Southwest Florida Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Popular airline
Delta
Distance
1980 km
Average flight time
3 hours 4 mins