Flights from Southern Illinois

Cheapest flights from Southern Illinois

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 26 - Sat, Oct 10

STL

Lambert-St. Louis Intl.

DEN

Denver Intl.

$78 Roundtrip, found 5 days ago

$78

Roundtrip

found 5 days ago

Select Frontier Airlines flight, departing Sat, Sep 26 from Lambert-St. Louis Intl. to Denver Intl., returning Sat, Oct 10, priced at $78 found 5 days ago

Sat, Sep 26 - Wed, Oct 14

STL

Lambert-St. Louis Intl.

DEN

Denver Intl.

$128 Roundtrip, found 5 days ago

$128

Roundtrip

found 5 days ago

Select Frontier Airlines flight, departing Sat, Sep 26 from Lambert-St. Louis Intl. to Denver Intl., returning Wed, Oct 14, priced at $128 found 5 days ago

Mon, Nov 16 - Tue, Dec 1

STL

Lambert-St. Louis Intl.

MCO

Orlando Intl.

$133 Roundtrip, found 16 hours ago

$133

Roundtrip

found 16 hours ago

Select Frontier Airlines flight, departing Mon, Nov 16 from Lambert-St. Louis Intl. to Orlando Intl., returning Tue, Dec 1, priced at $133 found 16 hours ago

Wed, Nov 18 - Wed, Dec 2

EVV

Evansville Regional

MCO

Orlando Intl.

$137 Roundtrip, found 3 days ago

$137

Roundtrip

found 3 days ago

Select Breeze Airways flight, departing Wed, Nov 18 from Evansville Regional to Orlando Intl., returning Wed, Dec 2, priced at $137 found 3 days ago

Fri, Nov 6 - Mon, Nov 16

STL

Lambert-St. Louis Intl.

DFW

Dallas-Fort Worth Intl.

$148 Roundtrip, found 14 hours ago

$148

Roundtrip

found 14 hours ago

Select Frontier Airlines flight, departing Fri, Nov 6 from Lambert-St. Louis Intl. to Dallas-Fort Worth Intl., returning Mon, Nov 16, priced at $148 found 14 hours ago

Sat, Oct 10 - Thu, Oct 15

STL

Lambert-St. Louis Intl.

LAS

Harry Reid Intl.

$203 Roundtrip, found 2 hours ago

$203

Roundtrip

found 2 hours ago

Select Frontier Airlines flight, departing Sat, Oct 10 from Lambert-St. Louis Intl. to Harry Reid Intl., returning Thu, Oct 15, priced at $203 found 2 hours ago

Sat, Nov 7 - Wed, Nov 18

STL

Lambert-St. Louis Intl.

LAX

Los Angeles Intl.

$205 Roundtrip, found 19 hours ago

$205

Roundtrip

found 19 hours ago

Select Frontier Airlines flight, departing Sat, Nov 7 from Lambert-St. Louis Intl. to Los Angeles Intl., returning Wed, Nov 18, priced at $205 found 19 hours ago

Mon, Oct 5 - Thu, Oct 15

STL

Lambert-St. Louis Intl.

MIA

Miami Intl.

$208 Roundtrip, found 6 days ago

$208

Roundtrip

found 6 days ago

Select Frontier Airlines flight, departing Mon, Oct 5 from Lambert-St. Louis Intl. to Miami Intl., returning Thu, Oct 15, priced at $208 found 6 days ago

Wed, Oct 7 - Mon, Oct 12

STL

Lambert-St. Louis Intl.

MIA

Miami Intl.

$227 Roundtrip, found 2 days ago

$227

Roundtrip

found 2 days ago

Select American Airlines flight, departing Wed, Oct 7 from Lambert-St. Louis Intl. to Miami Intl., returning Mon, Oct 12, priced at $227 found 2 days ago

Wed, Sep 16 - Wed, Sep 23

STL

Lambert-St. Louis Intl.

TPA

Tampa Intl.

$232 Roundtrip, found 2 days ago

$232

Roundtrip

found 2 days ago

Select Frontier Airlines flight, departing Wed, Sep 16 from Lambert-St. Louis Intl. to Tampa Intl., returning Wed, Sep 23, priced at $232 found 2 days ago

Tue, Nov 17 - Tue, Dec 1

STL

Lambert-St. Louis Intl.

MCO

Orlando Intl.

$243 Roundtrip, found 16 hours ago

$243

Roundtrip

found 16 hours ago

Select Delta flight, departing Tue, Nov 17 from Lambert-St. Louis Intl. to Orlando Intl., returning Tue, Dec 1, priced at $243 found 16 hours ago

Wed, Dec 9 - Fri, Dec 11

CGI

Cape Girardeau Municipal

DFW

Dallas-Fort Worth Intl.

$243 Roundtrip, found 3 days ago

$243

Roundtrip

found 3 days ago

Select Contour Airlines flight, departing Wed, Dec 9 from Cape Girardeau Municipal to Dallas-Fort Worth Intl., returning Fri, Dec 11, priced at $243 found 3 days ago

Wed, Oct 7 - Wed, Oct 14

STL

Lambert-St. Louis Intl.

SAN

San Diego Intl.

$245 Roundtrip, found 19 hours ago

$245

Roundtrip

found 19 hours ago

Select Frontier Airlines flight, departing Wed, Oct 7 from Lambert-St. Louis Intl. to San Diego Intl., returning Wed, Oct 14, priced at $245 found 19 hours ago

Sat, Nov 21 - Thu, Nov 26

STL

Lambert-St. Louis Intl.

PHX

Sky Harbor Intl.

$283 Roundtrip, found 2 hours ago

$283

Roundtrip

found 2 hours ago

Select Frontier Airlines flight, departing Sat, Nov 21 from Lambert-St. Louis Intl. to Sky Harbor Intl., returning Thu, Nov 26, priced at $283 found 2 hours ago

Wed, Sep 30 - Sun, Oct 18

STL

Lambert-St. Louis Intl.

DEN

Denver Intl.

$287 Roundtrip, found 8 hours ago

$287

Roundtrip

found 8 hours ago

Select Southwest Airlines flight, departing Wed, Sep 30 from Lambert-St. Louis Intl. to Denver Intl., returning Sun, Oct 18, priced at $287 found 8 hours ago

Wed, Sep 30 - Sun, Oct 18

STL

Lambert-St. Louis Intl.

DEN

Denver Intl.

$287 Roundtrip, found 8 hours ago

$287

Roundtrip

found 8 hours ago

Select United flight, departing Wed, Sep 30 from Lambert-St. Louis Intl. to Denver Intl., returning Sun, Oct 18, priced at $287 found 8 hours ago

Wed, Oct 28 - Mon, Nov 9

PAH

Barkley Regional

LAX

Los Angeles Intl.

$348 Roundtrip, found 12 hours ago

$348

Roundtrip

found 12 hours ago

Select United flight, departing Wed, Oct 28 from Barkley Regional to Los Angeles Intl., returning Mon, Nov 9, priced at $348 found 12 hours ago

Tue, Oct 13 - Sat, Oct 24

STL

Lambert-St. Louis Intl.

LAS

Harry Reid Intl.

$395 Roundtrip, found 3 days ago

$395

Roundtrip

found 3 days ago

Select Alaska Airlines flight, departing Tue, Oct 13 from Lambert-St. Louis Intl. to Harry Reid Intl., returning Sat, Oct 24, priced at $395 found 3 days ago

Tue, Dec 8 - Sat, Dec 12

EVV

Evansville Regional

PHX

Sky Harbor Intl.

$491 Roundtrip, found 17 hours ago

$491

Roundtrip

found 17 hours ago

Select Delta flight, departing Tue, Dec 8 from Evansville Regional to Sky Harbor Intl., returning Sat, Dec 12, priced at $491 found 17 hours ago

Sat, Sep 12 - Tue, Sep 15

EVV

Evansville Regional

LAS

Harry Reid Intl.

$544 Roundtrip, found 1 day ago

$544

Roundtrip

found 1 day ago

Select Delta flight, departing Sat, Sep 12 from Evansville Regional to Harry Reid Intl., returning Tue, Sep 15, priced at $544 found 1 day ago