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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property
Hotel in St. Louis with free breakfast and a 24-hour fitness center

Choose dates to view prices

Located in the business district, Holiday Inn Express & Suites St. Louis South - I-55 offers practical comforts for busy travelers. Enjoy a hearty breakfast buffet, reliable in-room WiFi, an indoor pool for relaxation, and a 24-hour gym.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pool
  • Housekeeping
  • 24/7 front desk
  • Air conditioning

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Room amenity

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.4 out of 10
Exceptional
(13 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub) | In-room safe, desk, laptop workspace, blackout drapes

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Hair dryer
  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Room amenity

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.4 out of 10
Exceptional
(26 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
  • 28 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Room amenity

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Free toiletries, hair dryer, towels, soap

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(1 review)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.0 out of 10
Wonderful
(4 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Room amenity

Standard Room, 1 King Bed (Bath Shwr Combo)

9.8 out of 10
Exceptional
(15 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room

Standard Room | In-room safe, desk, laptop workspace, blackout drapes

Standard Room

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 2
  • 1 Twin Bed

View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living) | In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Highlights

Air conditioning
Heating
Connecting rooms available
Free rollaway/extra beds
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
  • 28 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Room amenity

Standard Room, 2 Queen Beds

9.4 out of 10
Exceptional
(72 reviews)

Highlights

Air conditioning
Heating
Connecting rooms available
Free cribs/infant beds
Refrigerator
Flat-screen TV
Blackout drapes/curtains
Shower/tub combination
  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the neighborhood

Map
4250 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • Barnes Jewish South Campus - 5 min walk - 0.3 miles
  • Gateway Arch - 17 min drive - 17.3 miles
  • Enterprise Center - 17 min drive - 16.7 miles
  • St. Louis Union Station - 18 min drive - 16.9 miles
  • St. Louis Zoo - 21 min drive - 16.4 miles

Getting around

  • Kirkwood Station - 17 min drive
  • St. Louis Lambert Intl. Airport (STL) - 32 min drive

Restaurants

  • ‪Burger King - ‬10 min walk
  • ‪Popeyes Louisiana Kitchen - ‬4 min walk
  • ‪Starbucks - ‬9 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive
  • ‪Hardee's / Red Burrito - ‬11 min walk

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Hotel in the business district
A free breakfast buffet, a 24-hour gym, and a business center are just a few of the amenities provided at Holiday Inn Express & Suites St. Louis South - I-55 by IHG. Stay connected with free in-room WiFi.
You'll also enjoy perks such as:
  • An indoor pool along with sun loungers
  • Free self parking
  • A 24-hour front desk, meeting rooms, and an elevator
  • A front-desk safe, a vending machine, and smoke-free premises
  • Guest reviews say great things about the breakfast and helpful staff
Room features
All 99 rooms offer comforts such as laptop-friendly workspaces and air conditioning, as well as thoughtful touches like free WiFi and safes. Guest reviews highly rate the clean rooms at the property.
More amenities include:
  • Bathrooms with free toiletries and hair dryers
  • 49-inch flat-screen TVs with cable channels
  • Wardrobes/closets, refrigerators, and microwaves

Similar properties

Exterior
Fairfield Inn & Suites by Marriott St. Louis South
  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
9.6 out of 10, Exceptional, 321 reviews
Fairfield Inn & Suites by Marriott St. Louis South

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • At least 10% of profits reinvested in community and sustainability
  • Banquet hall
  • No plastic drinking straws
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Free cribs are available on request at the property

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Frequently asked questions

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–10 PM.

Is Holiday Inn Express & Suites St. Louis South - I-55 by IHG pet-friendly?

No, only service animals are welcome at the property.

How much is parking?

Self parking is free at this property.

What time is check-in at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM.

What time is check-out at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express & Suites St. Louis South - I-55 by IHG located?

Situated in the business district, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 mi (5 km) of St Anthony's and Kindred Hospital St. Louis South. Kennedy Rink is 3.1 mi (5 km) away.

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Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 800 out of 1001 reviews
Rating 8 - Good. 145 out of 1001 reviews
Rating 6 - Okay. 36 out of 1001 reviews
Rating 4 - Poor. 14 out of 1001 reviews
Rating 2 - Terrible. 6 out of 1001 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.6/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness

Reviews

10/10 Excellent

Kalina

Staff was extremely helpful
Stayed 1 night in Nov 2025

8/10 Good

Ruth

Liked: Cleanliness, staff & service, property conditions & facilities
cleaning staff was very helpful and I loved the cookies at night
Stayed 4 nights in Oct 2025

10/10 Excellent

Zumret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent
Stayed 2 nights in Aug 2025

10/10 Excellent

Ashley

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was clean. The breakfast is pretty decent. Several different options to choose from. It’s in a quiet part of town. I would definitely stay there again!
Stayed 3 nights in Oct 2025

10/10 Excellent

Jacob

Liked: Cleanliness, staff & service, property conditions & facilities
Very safe, quiet, clean, and the staff were amazing. Ill definitely be back!
Stayed 2 nights in Sep 2025

10/10 Excellent

Ray

Liked: Cleanliness, staff & service, property conditions & facilities
Great hotel
Stayed 6 nights in Jul 2025

10/10 Excellent

Ryan Gerald

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice people, clean room, good breakfast
Stayed 1 night in Jul 2025

10/10 Excellent

Tameka

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay and clean hotel. I had a double queen and the room was very spacious. Great breakfast option and friendly staff.
Stayed 1 night in Aug 2025

10/10 Excellent

James

Very nice new hotel and even the breakfast was great.
Stayed 2 nights in Jul 2025

10/10 Excellent

Jessica

Great breakfast, great rooms and comfy beds.
Stayed 1 night in May 2025

10/10 Excellent

sonia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location and service
Stayed 1 night in Jul 2025

10/10 Excellent

Cresley

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I have stayed at this property multiple times and it’s always a good experience. The staff are friendly and do an excellent job at keeping up the facility. I look forward to returning.
Stayed 1 night in Aug 2025

10/10 Excellent

Kevan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Good clean hotel.
Stayed 1 night in Jun 2025

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good and the hotel staff was the best made it worth the trip
Stayed 2 nights in Jun 2025

10/10 Excellent

John

Liked: Cleanliness, amenities, property conditions & facilities
Our family loved cookie hour!
Stayed 3 nights in Jul 2025

10/10 Excellent

James

Liked: Cleanliness, staff & service, property conditions & facilities
Friendly staff, great location!
Stayed 1 night in Apr 2025

10/10 Excellent

Angela

Liked: Cleanliness, amenities, property conditions & facilities
Charcoal grills, outside seating for breakfast and library tables.
Stayed 5 nights in Jul 2025

10/10 Excellent

Linhan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
good
Stayed 1 night in Sep 2025

10/10 Excellent

Berta

Liked: Cleanliness, amenities, property conditions & facilities
I was in a convention in St Louis, I stayed at this hotel and it was so convenient going in hwy. The place is clean and upgraded front desk vey helpful.
Stayed 2 nights in Jul 2025

8/10 Good

Anand

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
For breakfast, they had food for vegeterians, but limited choices. I wish next time they will have more choices in hot dishes for Vegeterians other then bread, oat, serials, milk, patatoes.
Stayed 1 night in Sep 2025

10/10 Excellent

Charles

Liked: Cleanliness, staff & service, property conditions & facilities
Staff was very friendly and breakfast options were hot and tasty!
Stayed 1 night in Apr 2025

10/10 Excellent

Susan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location, wonderful staff, very clean
Stayed 1 night in Mar 2025

8/10 Good

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great distance from the city where you weren't over crowded with city life but weren't too far away that it took a long time to get to anything fun.
Stayed 3 nights in May 2025

10/10 Excellent

Porsha

Liked: Cleanliness, amenities, property conditions & facilities
Room was clean. People were very friendly. Would stay here again.
Stayed 2 nights in Jun 2025

10/10 Excellent

Joan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The staff was excellent. Our room was clean and comfortable. The couch as a bit dated But are stay was good
Stayed 1 night in Jun 2025
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