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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Property class: 2.5

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Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

A hotel room with a bed, a TV, a desk, a chair, and a sofa. - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
A gym with exercise equipment, a mirror, and a television. - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers. - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table. - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
A conference room with multiple tables and chairs, large windows with a view of the street, and a clock on the wall. - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Located close to Buffalo Music Hall of Fame and Market Arcade Building, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG provides a free breakfast buffet, dry cleaning/laundry services, and a gym. In addition to a business center, guests can connect to free in-room WiFi.

Reviews

8.4 out of 10
Very good

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Off-peak, on budget: 30% or more off select hotels in our fall sale

Skip the crowds, keep the savings. AARP members save more after Labor Day. Book by Oct 7, 2026.

Room options

Available filters for rooms
Showing 7 of 7 rooms

View all photos for Standard Room

A bed with white bedding and pillows against a brown headboard.

Standard Room

9.2 out of 10
Wonderful
(32 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom

A hotel room with a bed, a desk, a chair, a TV, and a sofa.

Suite, 1 Bedroom

8.8 out of 10
Excellent
(71 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

A bathroom with a shower, a sink, a toilet, and a mirror.

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

A bathroom with a shower, a sink, a toilet, and a mirror.

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

DOUBLE Accessible-Queen Size Bed

  • Sleeps 4
  • Free WiFi

DOUBLE KING SIZE BED

  • Sleeps 4
  • Free WiFi

Room TWO BEDS

  • Sleeps 10
  • Free WiFi

About the neighborhood

Located in Downtown Buffalo, a neighborhood in Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is in the entertainment district and near a metro station. CEPA Gallery and Road Less Traveled Productions are cultural highlights, and some of the area's popular attractions include Market Arcade Building and Shea's Performing Arts Center. Andrews Theatre and Fountain Plaza are two other places to visit that come recommended. Spend some time exploring the area's activities, including golfing. Visit our Buffalo travel guide
Map
601 Main St, Buffalo, NY, 14203

What's nearby

  • A dessert with a chocolate topping, a scoop of ice cream, and a berry garnish on a plate.
    Chippewa District
    1 min walk - 0.0 miles
  • A tall obelisk monument surrounded by a landscaped garden with statues, set against a backdrop of historic buildings and a clear blue sky.
    Niagara Square
    8 min walk - 0.5 miles
  • Shea's Performing Arts Center
    2 min walk - 0.1 miles
  • Fountain Plaza
    2 min walk - 0.1 miles
  • Buffalo Convention Center
    6 min walk - 0.4 miles

Getting around

  • Fountain Plaza Station
    1 min walk
  • Buffalo-Exchange Street Station
    18 min walk
  • Buffalo Niagara Intl. Airport (BUF)
    21 min drive

Restaurants

  • Sidelines Sports Bar and Grill
    6 min walk
  • Tap House Pub & Grill
    4 min walk
  • Big Ditch Brewing Company
    4 min walk
  • SPoT Coffee
    4 min walk
  • Patina 250
    5 min walk

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Some LED lighting used
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Children up to the age of 18 years can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Nearby parking fee: USD 16.00 per day (500 ft away)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property

We should mention

Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG pet-friendly?

No, only service animals are welcome at the property.

What time is check-in at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

What time is check-out at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG located?

Located in Downtown Buffalo, this hotel is steps from Market Arcade Building, Buffalo Music Hall of Fame, and CEPA Gallery. Buffalo Visitor Center and Fountain Plaza are just steps away. Fountain Plaza Station is only a 2-minute walk and Lafayette Square Station is 5 minutes.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

8.4

Very Good

8.8

Cleanliness

8.2

Amenities

8.8

Staff & service

8.6

Property conditions & facilities
Rating 10 - Excellent. 554 out of 1015 reviews
Rating 8 - Good. 266 out of 1015 reviews
Rating 6 - Okay. 91 out of 1015 reviews
Rating 4 - Poor. 45 out of 1015 reviews
Rating 2 - Terrible. 59 out of 1015 reviews

Reviews

Verified review

10/10 Excellent

Lydia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We really enjoy this hotel. The staff is so friendly we decided to stay here a second time. The breakfast was okay. The room was nice and spacious.
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

james

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

mary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good price and location. Very comfortable bed and big clean room
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Danyal

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great breakfast, clean room and great location
Stayed 1 night in Jun 2026
Verified review

8/10 Good

Vashi

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice, quiet hotel... right downtown... great location
Stayed 1 night in Jul 2026
Verified review

8/10 Good

Anna

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fresh breakfast, coffee smelled good when we entered the lobby this morning!
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Noelle

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Was a great stay over night and the room was a great size, clean and the bed was very comfortable. Breakfast was very good.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Diana

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fabulous location. Staff was very helpful and accommodating.
Stayed 1 night in Jul 2026
Verified review

8/10 Good

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location. Spacious clean room. Adequate breakfast. Parking situation not great. Staff did job not overly friendly or welcoming
Stayed 1 night in Aug 2026
Verified review

8/10 Good

Saaida

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Front desk was welcoming and super friendly
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Kate

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Heather was amazing at the breakfast station all morning!!!! Rooms were very clean and great to stay in!
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Kevin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean. Staff was helpful with local attractions/parking. Close to the train.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Linda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice room, good breakfast with many choices, no on site parking
Stayed 1 night in May 2026
Verified review

8/10 Good

Paul

Liked: Staff & service, amenities, property conditions & facilities
Great location and very helpful staff. Room a bit dated and musty smell but good value overall.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Pamela

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Close to everything. A beautiful walk to the canal. Comfy bed.
Stayed 3 nights in Jun 2026
Verified review

8/10 Good

Janine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was great and staff was friendly and helpful.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel and great location with an awesome staff. Byron was especially friendly and helpful! Nice breakfast included as well.
Stayed 1 night in Apr 2026
Verified review

8/10 Good

Daniel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice room, clean, convenient location to why we were in town. However the recommended parking was off-site and about 2 blocks away. Having to walk that multiple times was a bit annoying.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Javier

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Tony at the front desk was so professional and helpful with recommendations. He made sure we had a nice stay during our time in Buffalo. Clean and spacious room.
Stayed 2 nights in May 2026
Verified review

8/10 Good

Brooke

Liked: Cleanliness, property conditions & facilities
Overall it was a good booking, a little trash under bed, a little Trouble at first with our booking but, once we were set staff was amazing, along with security!!
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Eric

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Roo.s were clean. Was close to a lot of venues downtown
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Rossana

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
On a business trip. Hotel was clean, comfortable and close to restaurants. there is an upscale Indian restaurant attached to the hotel. I did not try it, but it will be on my list for my next visit. The hotel is near hospitals and the Roswell Cancer Center which was an easy, safe and pleasant 20 minute walk. Definitely will stay here again. Thank you to all the staff for making my visit comfortable and pleasant.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were there for a concert at Town Ballroom which is two blocks away. Breakfast was good. Parking is a block away in a public parking garage.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026