Uptown Greenwood Vacation Packages for 2026

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Top Hotel Deals

Inn on the Square, an Ascend Collection Hotel

Inn on the Square, an Ascend Collection Hotel

3 out of 5
104 Court Avenue East Greenwood SC
0.14 km from Uptown Greenwood
Book a stay at this business-friendly hotel in Greenwood. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean ...
Holiday Inn Express & Suites Greenwood Mall by IHG

Holiday Inn Express & Suites Greenwood Mall by IHG

2.5 out of 5
300 North Creek Boulevard Greenwood SC
3.39 km from Uptown Greenwood
Book a stay at this business-friendly hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Greenwood Country Club and Josephine ...
Baymont by Wyndham Greenwood

Baymont by Wyndham Greenwood

2.5 out of 5
109 Enterprise Ct Greenwood SC
3.28 km from Uptown Greenwood
Book a stay at this business-friendly hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Comfort Inn & Suites Greenwood near University

Comfort Inn & Suites Greenwood near University

2.5 out of 5
110 Birchtree Dr Greenwood SC
2.68 km from Uptown Greenwood
Book a stay at this golf hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
The Belmont Inn

The Belmont Inn

2 out of 5
104 East Pickens St Abbeville SC
19.99 km from Uptown Greenwood
Stay at this hotel in Abbeville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Lakefront House w/ Boat Ramp, Dock & Sunset Views!

Lakefront House w/ Boat Ramp, Dock & Sunset Views!

3 out of 5
Cross Hill SC
18.26 km from Uptown Greenwood
Book a stay at this business-friendly cottage in Cross Hill. Enjoy free parking, in-room fireplaces, and air conditioning. Popular attractions Lighthouse Marina ...
Red Roof Inn & Suites Greenwood, SC

Red Roof Inn & Suites Greenwood, SC

2 out of 5
919 Montague Ave Greenwood SC
3.19 km from Uptown Greenwood
Book a stay at this business-friendly hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Fairfield Inn & Suites by Marriott Greenwood

Fairfield Inn & Suites by Marriott Greenwood

3 out of 5
527 Bypass 72 NW Greenwood SC
3.38 km from Uptown Greenwood
Book a stay at this business-friendly hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Quality Inn Greenwood Hwy 25

Quality Inn Greenwood Hwy 25

2.5 out of 5
719 Bypass 25 NE Greenwood SC
2.85 km from Uptown Greenwood
Book a stay at this business-friendly hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Greenwood Civic Center and Emerald ...
Hampton Inn Greenwood

Hampton Inn Greenwood

2.5 out of 5
1624 Bypass 72 Ne Greenwood SC
3.13 km from Uptown Greenwood
Stay at this hotel in Greenwood. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Josephine B. Abney Cultural Center and Greenwood Civic ...
Don't see what you're looking for?
See all available properties in Uptown Greenwood
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Aug 27 - Wed, Sep 9
DCA
Ronald Reagan Washington National
GSP
Greenville-Spartanburg Intl.
$197 Roundtrip, found 4 days ago
$197
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Aug 27 from Ronald Reagan Washington National to Greenville-Spartanburg Intl., returning Wed, Sep 9, priced at $197 found 4 days ago
American Airlines
Fri, Aug 28 - Sun, Aug 30
DCA
Ronald Reagan Washington National
CAE
Columbia Metropolitan
$259 Roundtrip, found 4 days ago
$259
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Aug 28 from Ronald Reagan Washington National to Columbia Metropolitan, returning Sun, Aug 30, priced at $259 found 4 days ago
Southwest Airlines
Thu, Nov 5 - Mon, Nov 9
DAL
Love Field
GSP
Greenville-Spartanburg Intl.
$365 Roundtrip, found 18 hours ago
$365
Roundtrip
found 18 hours ago
Select Southwest Airlines flight, departing Thu, Nov 5 from Love Field to Greenville-Spartanburg Intl., returning Mon, Nov 9, priced at $365 found 18 hours ago
United
Fri, Dec 25 - Wed, Jan 6
DFW
Dallas-Fort Worth Intl.
GSP
Greenville-Spartanburg Intl.
$423 Roundtrip, found 18 hours ago
$423
Roundtrip
found 18 hours ago
Select United flight, departing Fri, Dec 25 from Dallas-Fort Worth Intl. to Greenville-Spartanburg Intl., returning Wed, Jan 6, priced at $423 found 18 hours ago