Hampton Inn & Suites St. Louis/South I-55
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Hampton Inn & Suites St. Louis/South I-55 combines comfort with practicality in an ideal location. Guests enjoy a satisfying breakfast buffet each morning, can relax beside the welcoming lobby fireplace, or take advantage of the indoor swimming pool during their stay.
Reviews
9.6 out of 10
Exceptional
Popular amenities
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9.8 out of 10
Exceptional
(41 reviews)
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9.6 out of 10
Exceptional
(14 reviews)
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9.6 out of 10
Exceptional
(4 reviews)
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Room
10.0 out of 10
Exceptional
(2 reviews)
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Two Queen Beds, Non-Smoking, Accessible
9.8 out of 10
Exceptional
(27 reviews)
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One King Bed, Non-Smoking, Accessible
9.8 out of 10
Exceptional
(20 reviews)
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Studio, Accessible, Non Smoking
8.0 out of 10
Very good
(6 reviews)
About the neighborhood

4200 Midamerica Lane, St. Louis, MO, 63129
What's nearby
Busch Stadium16 min drive - 17.6 miles
Gateway Arch17 min drive - 18.0 miles
St. Louis Union Station18 min drive - 17.6 miles
St. Louis Zoo23 min drive - 22.2 miles- Barnes Jewish South Campus6 min walk - 0.4 miles
Getting around
- Kirkwood Station14 min drive
- St. Louis Lambert Intl. Airport (STL)31 min drive
Restaurants
- McDonald's3 min drive
- Burger King10 min walk
- Popeyes Louisiana Kitchen3 min walk
- Hardee's / Red Burrito10 min walk
- Rich & Charlie's Italian Restaurant3 min drive
About this property
Hampton Inn & Suites St. Louis/South I-55
Similar properties

Best Western St. Louis Inn
St. Louis
Best Western St. Louis Inn
- Pool
- Breakfast included
- Pet friendly
- Kids pool
8.2 out of 10, Very Good, 1,007 reviews
Property amenities
Room amenities
Policies
Important information
Optional extras
- Pet fee: USD 75 per accommodation, per stay
- Service animals are exempt from fees
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
We should mention
Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Property is also known as
Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55
Frequently asked questions
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Reviews
Hampton Inn & Suites St. Louis/South I-55 Reviews
9.6
Exceptional
9.8
Cleanliness
9.2
Location
9.8
Staff & service
9.6
Property conditions & facilities
Reviews
Verified
Apr 17, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stayed 1 night in Apr 2026
Verified
10/10 Excellent
Kim
Apr 21, 2026
Liked: Cleanliness, staff & service, property conditions & facilities
Kim
Stayed 1 night in Apr 2026
Verified
10/10 Excellent
winnie
Mar 30, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
winnie
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
mary
Apr 16, 2026
Liked: Cleanliness, staff & service, property conditions & facilities
mary
Stayed 5 nights in Apr 2026
Verified
10/10 Excellent
Jennifer
Mar 30, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Jennifer
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Kathleen
Mar 8, 2026
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Kathleen
Stayed 1 night in Mar 2026
Verified
10/10 Excellent
Charles
Feb 14, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Charles
Stayed 1 night in Feb 2026
Verified
10/10 Excellent
Jerry
Sep 21, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Jerry
Stayed 1 night in Sep 2025
Verified
10/10 Excellent
Miliska
Jan 5, 2026
Liked: Cleanliness, staff & service, amenities
Miliska
Stayed 1 night in Jan 2026
Verified
8/10 Good
Jeffrey
Dec 6, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Jeffrey
Stayed 1 night in Dec 2025
Verified
10/10 Excellent
Manivannan
Dec 29, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Manivannan
Stayed 1 night in Dec 2025
Verified
10/10 Excellent
Amy
Nov 17, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amy
Stayed 1 night in Nov 2025
Verified
10/10 Excellent
Renee
Oct 11, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Renee
Stayed 1 night in Oct 2025
Verified
10/10 Excellent
Eric
Oct 19, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Eric
Stayed 1 night in Oct 2025
Verified
10/10 Excellent
Michael
Oct 23, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Michael
Stayed 1 night in Oct 2025
Verified
10/10 Excellent
Jane
Jun 17, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Jane
Stayed 2 nights in Jun 2025
Verified
10/10 Excellent
SHELLY
Dec 8, 2025
Liked: Cleanliness, staff & service, amenities
SHELLY
Stayed 1 night in Dec 2025
Verified
10/10 Excellent
Brittany
Jul 27, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Brittany
Stayed 1 night in Jul 2025
Verified
10/10 Excellent
Angie
May 12, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great stay
Angie
Stayed 2 nights in Feb 2025
Verified
10/10 Excellent
Sandro
Jun 16, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Sandro
Stayed 2 nights in Jun 2025
Verified
10/10 Excellent
John
Jul 15, 2025
John
Stayed 2 nights in Jul 2025
Verified
10/10 Excellent
Shannon
Dec 19, 2024
Liked: Cleanliness, staff & service, property conditions & facilities
Shannon
Stayed 1 night in Dec 2024
Verified
8/10 Good
Michael
Jan 18, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Michael
Stayed 4 nights in Dec 2024
Verified
10/10 Excellent
Michael
May 29, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Quick trip
Michael
Stayed 1 night in May 2025
Verified
10/10 Excellent
Damon
Mar 29, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Damon
Stayed 2 nights in Mar 2025








