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Hampton Inn & Suites St. Louis/South I-55

Property class: 2.5

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Photo gallery for Hampton Inn & Suites St. Louis/South I-55

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools. - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
A modern kitchen with a sink, dishwasher, and microwave. There is a large mirror above the sink and a countertop with various items. The room has a neutral color scheme and a view of a living area with a couch and a TV. - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
A gym with treadmills, exercise bikes, and a mirror. - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
Unclassified image, 4 of 71, button - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
A snack display area with various packaged snacks and a refrigerated section. - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
Take advantage of a free breakfast buffet, a grocery/convenience store, and dry cleaning/laundry services at Hampton Inn & Suites St. Louis/South I-55. Free in-room WiFi is available to all guests, along with a fireplace in the lobby and a gym.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning

Off-peak, on budget: 30% or more off select hotels in our fall sale

Skip the crowds, keep the savings. AARP members save more after Labor Day. Book by Oct 7, 2026.

Room options

Available filters for rooms
Showing 10 of 10 rooms

1 King Bed Nonsmoking

  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.8 out of 10
Exceptional
(41 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.8 out of 10
Exceptional
(17 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

9.2 out of 10
Wonderful
(5 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Room

A neatly made bed with white pillows and a single brown pillow, and a sign on the brown pillow indicating a Hampton HOME collection.

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

View all photos for Two Queen Beds, Non-Smoking, Accessible

A hotel room with a bed, desk, chair, television, and a minibar.

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(28 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

View all photos for One King Bed, Non-Smoking, Accessible

A hotel room with a large bed, two bedside lamps, a nightstand with a phone, and a door to another room.

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(23 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free wired internet

View all photos for Studio, Accessible, Non Smoking

A hotel room with a bed, a desk with a telephone, a chair, a sofa, a lamp, and a painting on the wall.

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free wired internet

2 Queen Beds Nonsmoking

  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

View all photos for 2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.

2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

  • Sleeps 4
  • 2 Queen Beds
  • Free wired internet

About the neighborhood

St. Louis is home to Hampton Inn & Suites St. Louis/South I-55. St. Louis Zoo is a popular attraction and the area's natural beauty can be seen at Mississippi River and Forest Park. BounceU of St. Louis and Kennedy Rink are also worth visiting. Visit our St. Louis travel guide
Map
4200 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.
    Busch Stadium
    16 min drive - 17.6 miles
  • The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.
    Gateway Arch
    17 min drive - 18.0 miles
  • A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.
    Enterprise Center
    17 min drive - 18.2 miles
  • A historic building with a clock tower and red-roofed structures.
    St. Louis Union Station
    18 min drive - 17.6 miles
  • A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.
    St. Louis Zoo
    23 min drive - 22.2 miles

Getting around

  • Kirkwood Station
    14 min drive
  • St. Louis Lambert Intl. Airport (STL)
    31 min drive

Restaurants

  • McDonald's
    3 min drive
  • Burger King
    10 min walk
  • Hardee's / Red Burrito
    10 min walk
  • Subway
    3 min drive
  • Popeyes Louisiana Kitchen
    3 min walk

Similar properties

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.
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  • Pool
  • Breakfast included
  • Parking included
  • Free WiFi
9.6 out of 10, Exceptional, 1,002 reviews
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business center
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight

Contactless check-in available

Express check-in available

Check-out

Check-out before 11 AM

Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 75 per accommodation, per stay

Service animals are welcome, and are exempt from fees

Welcoming dogs and cats only

2 total pets

Pets cannot be left unattended

Children and extra beds

Children are welcome

Rollaway/extra beds are not available

Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Does Hampton Inn & Suites St. Louis/South I-55 have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–10 PM.

Is Hampton Inn & Suites St. Louis/South I-55 pet-friendly?

Yes, Hampton Inn & Suites St. Louis/South I-55 allows cats and dogs (limit 2 total). There's a fee of USD 75 per accommodation, per stay. Service animals are exempt from fees.

How much is parking?

Self parking is free at this property.

What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Hampton Inn & Suites St. Louis/South I-55?

Check-out is at 11 AM.

Where is Hampton Inn & Suites St. Louis/South I-55 located?

Situated in St. Louis, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 mi (5 km) of BounceU of St. Louis and St Anthony's. Suson Park and Kindred Hospital St. Louis South are also within 3 mi (5 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Hampton Inn & Suites St. Louis/South I-55 Reviews

9.6

Exceptional

9.6

Cleanliness

9.2

Location

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 814 out of 1000 reviews
Rating 8 - Good. 134 out of 1000 reviews
Rating 6 - Okay. 27 out of 1000 reviews
Rating 4 - Poor. 5 out of 1000 reviews
Rating 2 - Terrible. 20 out of 1000 reviews

Reviews

Verified review

10/10 Excellent

Shannon

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff, very clean room and building.
Stayed 2 nights in Aug 2026
Verified review

10/10 Excellent

Holly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean, safe, and comfortable!
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Nguyen Bao Chau

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very quiet area. The room so clean and staffs were super helpful. Will be coming back.
Stayed 1 night in Aug 2026
Verified review

6/10 Okay

darrel

Liked: Cleanliness
Room was clean and breakfast was excellent. But bed was older and squeezing and pillows need to be replaced and the A/C only went to 68 would be the only negative.
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Shawn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing hotel and staff
Stayed 8 nights in May 2026
Verified review

10/10 Excellent

Cristal

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean and comfortable
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Jenny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly, breakfast was delicious. I really enjoyed my stay
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Katrina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, polite staff, great location
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Kim

Liked: Cleanliness, staff & service, property conditions & facilities
Parking felt safe , nice staff
Stayed 1 night in Apr 2026
Verified review

8/10 Good

Lora

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Parking was great, very close to all highways, staff super friendly, and room was great. Food not the best to me but I would stay here again.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

winnie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room and good breakfast. We love stay in this hotel.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Arlene

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I had a great stay. Clean rooms and friendly staff
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Robin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Kudos to both the housecleaning staff for such a clean room & the breakfast attendants that were supervising the breakfast. They were all super friendly & helpful! Bed was comfy, loved the shower, breakfast was good, & so very happy that y'all allow dogs!!! I wish the pet fee was a little cheaper, though. We have stayed there before & will definitely stay again!
Stayed 3 nights in May 2026
Verified review

8/10 Good

Glenn R

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We stayed one night on our way back from Tulsa OK to Indianapolis. We were traveling with a small dog and needed space to walk her. We drove to area restaurants and stores and found them easily accessible without using the Interstate. The hotel was quiet and well kept, and the staff took care of our rather minor needs.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

mary

Liked: Cleanliness, staff & service, property conditions & facilities
Room was clean and comfortable Staff professional friendly and helpful Breakfast was great! Several choices.
Stayed 5 nights in Apr 2026
Verified review

10/10 Excellent

Alison

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The front desk attendant was very helpful and welcoming. I was impressed wit the cleanliness of our room and the hot breakfast options. Would definitely stay there again!
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
My cousins and I were in town to see the Chicago Cubs play the St Louis Cardinals. This Hampton Inn & Suites was the perfect place to stay for the night. It is about a 20-minute Uber ride to the park but worked really well for us. It was very clean. The room was clean. The lobby was clean. The breakfast in the morning was very good and quite delicious. The lady who worked at breakfast, I did not catch her name, was so kind and sweet. I always look for clean hotels and this one definitely was great!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Deloris

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was clean. Staff was courteous. The breakfast was average for 3 star hotel.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a great stay for us! Friendly desk and breakfast staff. Clean throughout the property! Very comfortable.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff and room was GREAT!!! Parking was great!! Room was clean and well stocked. Breakfast was good as always. Nice comfortable environment that makes you feel home away from home. We will be returning.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025
Verified review

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Everything was just about needed to be friendly staff. Would recommend !!
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Phyllis

Liked: Cleanliness, staff & service, amenities
Nice clean room spacious
Stayed 2 nights in Feb 2026
Verified review

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025
Verified review

10/10 Excellent

Jane

Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025