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Hampton Inn & Suites St. Louis/South I-55

2.5 star property
Travelers start their day with a hearty breakfast buffet at this convenient hotel, perfectly positioned for exploring the attractions of St. Louis

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Photo gallery for Hampton Inn & Suites St. Louis/South I-55

Lobby - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
Indoor pool - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
Fitness facility - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
One King Bed, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
Room | In-room safe, blackout drapes, iron/ironing board - Hampton Inn & Suites St. Louis/South I-55 (St. Louis)
Hampton Inn & Suites St. Louis/South I-55 combines comfort with practicality in an ideal location. Guests enjoy a satisfying breakfast buffet each morning, can relax beside the welcoming lobby fireplace, or take advantage of the indoor swimming pool during their stay.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning

Room options

Available filters for rooms
Showing 10 of 10 rooms

1 King Bed Nonsmoking

  • Sleeps 2
  • Free WiFi

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.8 out of 10
Exceptional
(41 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(15 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

9.6 out of 10
Exceptional
(4 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Room

In-room safe, blackout drapes, iron/ironing board

Room

10.0 out of 10
Exceptional
(2 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

Two Queen Beds, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(28 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible | In-room safe, blackout drapes, iron/ironing board

One King Bed, Non-Smoking, Accessible

9.8 out of 10
Exceptional
(22 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking | In-room safe, blackout drapes, iron/ironing board

Studio, Accessible, Non Smoking

8.0 out of 10
Very good
(6 reviews)
  • 43 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

2 Queen Beds Nonsmoking

  • Sleeps 4
  • Free WiFi

View all photos for 2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

In-room safe, blackout drapes, iron/ironing board

2 QUEENS MOBILITY/HEARING ACCESS TUB NOSMOK

  • Sleeps 4
  • Free WiFi

About the neighborhood

St. Louis is home to Hampton Inn & Suites St. Louis/South I-55. St. Louis Zoo is a popular attraction and the area's natural beauty can be seen at Mississippi River and Forest Park. Kennedy Rink and Grant's Farm are also worth visiting. Visit our St. Louis travel guide
Map
4200 Midamerica Lane, St. Louis, MO, 63129

What's nearby

  • Busch Stadium
    Busch Stadium
    16 min drive - 17.3 miles
  • Gateway Arch
    Gateway Arch
    17 min drive - 17.8 miles
  • Union Station, St. Louis, MO
    St. Louis Union Station
    18 min drive - 17.4 miles
  • Forest Park
    Forest Park
    20 min drive - 20.2 miles
  • St. Louis Zoo
    St. Louis Zoo
    23 min drive - 22.2 miles

Getting around

  • Kirkwood Station
    14 min drive
  • St. Louis Lambert Intl. Airport (STL)
    31 min drive

Restaurants

  • McDonald's
    3 min drive
  • Burger King
    10 min walk
  • Popeyes Louisiana Kitchen
    3 min walk
  • Hardee's / Red Burrito
    10 min walk
  • Rich & Charlie's Italian Restaurant
    3 min drive

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM
  • Coffee and tea in common areas

Things to do

  • Gym
  • Indoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • 753 square feet of conference space
  • Business center
  • Computer station
  • Meeting room

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 5 floors
  • Banquet hall
  • Built in 2010
  • Fireplace in lobby
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 37-inch LCD TV with cable channels
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Free weekday newspapers
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Express check-in available

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 75 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total pets
Pets cannot be left unattended

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Pet fee: USD 75 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.

We should mention

Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Does Hampton Inn & Suites St. Louis/South I-55 have a pool?

Yes, this property has an indoor pool. Pool access is from 8 AM–10 PM.

Is Hampton Inn & Suites St. Louis/South I-55 pet-friendly?

Yes, Hampton Inn & Suites St. Louis/South I-55 allows cats and dogs (limit 2 total). There's a fee of USD 75 per accommodation, per stay. Service animals are exempt from fees.

How much is parking?

Self parking is free at this property.

What time is check-in at Hampton Inn & Suites St. Louis/South I-55?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Hampton Inn & Suites St. Louis/South I-55?

Check-out is at 11 AM.

Where is Hampton Inn & Suites St. Louis/South I-55 located?

Situated in St. Louis, this hotel is 0.3 mi (0.6 km) from Barnes Jewish South Campus and within 3 mi (5 km) of St Anthony's and Suson Park. Kennedy Rink is 3 mi (4.9 km) away.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Hampton Inn & Suites St. Louis/South I-55 Reviews

9.6

Exceptional

9.6

Cleanliness

9.2

Location

9.8

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 821 out of 1006 reviews
Rating 8 - Good. 133 out of 1006 reviews
Rating 6 - Okay. 27 out of 1006 reviews
Rating 4 - Poor. 5 out of 1006 reviews
Rating 2 - Terrible. 20 out of 1006 reviews

Reviews

Verified

10/10 Excellent

Shawn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing hotel and staff
Stayed 8 nights in May 2026
Verified

10/10 Excellent

Jenny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly, breakfast was delicious. I really enjoyed my stay
Stayed 1 night in Apr 2026
Verified

8/10 Good

Glenn R

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We stayed one night on our way back from Tulsa OK to Indianapolis. We were traveling with a small dog and needed space to walk her. We drove to area restaurants and stores and found them easily accessible without using the Interstate. The hotel was quiet and well kept, and the staff took care of our rather minor needs.
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Kim

Liked: Cleanliness, staff & service, property conditions & facilities
Parking felt safe , nice staff
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

winnie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room and good breakfast. We love stay in this hotel.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
My cousins and I were in town to see the Chicago Cubs play the St Louis Cardinals. This Hampton Inn & Suites was the perfect place to stay for the night. It is about a 20-minute Uber ride to the park but worked really well for us. It was very clean. The room was clean. The lobby was clean. The breakfast in the morning was very good and quite delicious. The lady who worked at breakfast, I did not catch her name, was so kind and sweet. I always look for clean hotels and this one definitely was great!
Stayed 1 night in May 2026
Verified

10/10 Excellent

Arlene

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I had a great stay. Clean rooms and friendly staff
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

mary

Liked: Cleanliness, staff & service, property conditions & facilities
Room was clean and comfortable Staff professional friendly and helpful Breakfast was great! Several choices.
Stayed 5 nights in Apr 2026
Verified

10/10 Excellent

Alison

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The front desk attendant was very helpful and welcoming. I was impressed wit the cleanliness of our room and the hot breakfast options. Would definitely stay there again!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff and room was GREAT!!! Parking was great!! Room was clean and well stocked. Breakfast was good as always. Nice comfortable environment that makes you feel home away from home. We will be returning.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a great stay for us! Friendly desk and breakfast staff. Clean throughout the property! Very comfortable.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Everything was just about needed to be friendly staff. Would recommend !!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Phyllis

Liked: Cleanliness, staff & service, amenities
Nice clean room spacious
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Really nice rooms and staff , good breakfast!
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Josi

Liked: Cleanliness, staff & service, amenities
Fast check in. Nice staff. Clean and quiet room!!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Miliska

Liked: Cleanliness, staff & service, amenities
The room was clean, modern, and pleasant. Staff members were welcoming, respectful, positive, and helpful.
Stayed 1 night in Jan 2026
Verified

8/10 Good

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The breakfast was good. The staff was friendly and they allowed us to check out late.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very clean, modern rooms with a welcoming staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Manivannan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Parking is Safe, Cleanliness is Good. Hospitality is Appreciable.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Big and comfortable rooms with excellent services
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was nice and friendly. Room was nice and clean.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Jane

Liked: Cleanliness, amenities, property conditions & facilities
The staff was wonderful and the location perfect!
Stayed 2 nights in Jun 2025
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the unique decor, the conference room, and the well attended bathrooms. Super helpful staff.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, property conditions & facilities
Everything was great! Clean, comfortable and breakfast was fantastic!
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

SHELLY

Liked: Cleanliness, staff & service, amenities
Clean room, good breakfast. Nice, safe area. But the staff was the best I have encountered in a long time. From check in, check out to the breakfast staff. I cannot say enough. We stayed 12/6/25 - one night and I would come back in a heartbeat.
Stayed 1 night in Dec 2025