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Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

3.0 star property
Travelers can start their day with a quick breakfast before settling into comfortable spaces designed for both productivity and relaxation

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Photo gallery for Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Terrace/patio - Home2 Suites By Hilton Sioux Falls/Sanford Medical Center (Sioux Falls)
Suite, 1 Bedroom, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi - Home2 Suites By Hilton Sioux Falls/Sanford Medical Center (Sioux Falls)
Indoor pool - Home2 Suites By Hilton Sioux Falls/Sanford Medical Center (Sioux Falls)
Studio Suite, 1 King Bed, Non Smoking | Living area | LCD TV - Home2 Suites By Hilton Sioux Falls/Sanford Medical Center (Sioux Falls)
Free daily on-the-go breakfast - Home2 Suites By Hilton Sioux Falls/Sanford Medical Center (Sioux Falls)
Located in central Sioux Falls, Home2 Suites By Hilton offers to-go breakfast, a 24-hour fitness center, indoor pool, business facilities, free parking, and luggage storage. Guests praise the attentive staff.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pool
  • Pet friendly
  • Parking included
  • Free WiFi
  • Air conditioning

Room options

Available filters for rooms
Showing 14 of 14 rooms

View all photos for Studio Suite, 1 King Bed, Non Smoking

Studio Suite, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Studio Suite, 1 King Bed, Non Smoking

9.4 out of 10
Exceptional
(28 reviews)
  • 40 sq m
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Non Smoking

Studio, 2 Queen Beds, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Non Smoking

9.4 out of 10
Exceptional
(13 reviews)
  • 40 sq m
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 Bedroom, Non Smoking

Suite, 1 Bedroom, Non Smoking | Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 Bedroom, Non Smoking

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 1 King Bed, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 1 King Bed, Accessible, Non Smoking

7.4 out of 10
Good
(3 reviews)
  • 40 sq m
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 1 King Bed, Accessible, Bathtub

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 1 King Bed, Accessible, Bathtub

9.6 out of 10
Exceptional
(4 reviews)
  • 40 sq m
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(4 reviews)
  • 40 sq m
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Accessible, Bathtub

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Accessible, Bathtub

9.0 out of 10
Wonderful
(2 reviews)
  • 40 sq m
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Studio, 2 Queen Beds, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Studio, 2 Queen Beds, Accessible, Non Smoking

9.2 out of 10
Wonderful
(5 reviews)
  • 40 sq m
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Bathtub

Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 King Bed, Accessible, Bathtub

10.0 out of 10
Exceptional
(1 review)
  • 49 sq m
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 King Bed, Accessible, Non Smoking

  • 49 sq m
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Desk, blackout drapes, iron/ironing board, free WiFi

Suite, 1 King Bed, Accessible, Non Smoking

  • 49 sq m
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

A hotel room with a desk, a sofa, a bed, a television, and a window.

Suite, 1 King Bed, Accessible, Non Smoking

  • Sleeps 4
  • Free WiFi

View all photos for Suite, 1 King Bed, Accessible, Bathtub

A hotel room with a desk, a sofa, a bed, a television, and a window.

Suite, 1 King Bed, Accessible, Bathtub

  • Sleeps 4
  • Free WiFi

View all photos for Studio, 1 King Bed, Accessible, Non Smoking

A hotel room with a bed, a sofa, a desk, a TV, and a window.

Studio, 1 King Bed, Accessible, Non Smoking

  • Sleeps 4
  • Free WiFi

About the neighborhood

University Heights, a neighborhood in Sioux Falls, is home to Home2 Suites By Hilton Sioux Falls/Sanford Medical Center. Sioux Empire Medical Museum and Edith Mortenson Theatre Center are cultural highlights, and some of the area's activities can be experienced at Denny Sanford Premier Center and Minnehaha Country Club. Looking to enjoy an event or a game while in town? See what's happening at Sioux Falls Stadium or Sioux Falls Convention Center. Visit our Sioux Falls travel guide
Map
1120 S Grange Ave, Sioux Falls, SD, 57105

What's nearby

  • Great Plains Zoo
    Great Plains Zoo
    3 min drive - 1.4 miles
  • Falls Park
    Falls Park
    4 min drive - 1.5 miles
  • University of Sioux Falls
    5 min walk - 0.3 miles
  • Augustana College
    11 min walk - 0.6 miles
  • Washington Pavilion of Arts and Science
    3 min drive - 1.1 miles

Getting around

  • Sioux Falls Regional Airport (FSD)
    8 min drive

Restaurants

  • Casey's
    12 min walk
  • Taco Bell
    14 min walk
  • Perch
    18 min walk
  • Taco John's
    3 min drive
  • Fryn' Pan
    2 min drive

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Free in-room WiFi has a 3-device limit
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free on-the-go breakfast available daily 6:00 AM to 9:00 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Indoor pool
  • Laundry facilities
  • Living room

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Housekeeping (weekly)

Business services

  • 950 square feet of conference space
  • Business center

Outdoors

  • Barbecue grill

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Braille/raised signage
  • Elevator
  • Phone accessibility kit
  • Stair-free path to entrance
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible van parking

More

  • 1 building
  • 4 floors
  • Built in 2014
  • Designated smoking areas (fines apply)

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed

Bathroom

  • Private bathroom
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 42-inch LCD TV

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Kitchen
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Iron/ironing board
  • Living room
  • Phone

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 11:00 PM
Early check-in subject to availability
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Late check-out subject to availability
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
This property doesn't offer after-hours check-in
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 50 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 50 lbs per pet)

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Pet fee: USD 50 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Noise-free guestrooms cannot be guaranteed

We should mention

The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Free in-room WiFi has a 3-device limit
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Does Home2 Suites By Hilton Sioux Falls/Sanford Medical Center have a pool?

Yes, this property has an indoor pool.

Is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center pet-friendly?

Yes, this property allows cats and dogs (limit 2 total) with a maximum weight of up to 50 lbs per pet. There's a fee of USD 50 per accommodation, per stay. Service animals are exempt from fees.

How much is parking?

Self parking is free at this property.

What time is check-in at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Check-in start time: 3:00 PM; Check-in end time: 11:00 PM. After-hours check-in is not available.

What time is check-out at Home2 Suites By Hilton Sioux Falls/Sanford Medical Center?

Check-out is at noon.

Where is Home2 Suites By Hilton Sioux Falls/Sanford Medical Center located?

Located in University Heights, this hotel is within a 5-minute walk of Sanford USD Medical Center, Sioux Empire Medical Museum, and University of Sioux Falls. Augustana College and Edith Mortenson Theatre Center are also within 15 minutes.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center Reviews

9.4

Exceptional

9.6

Cleanliness

9.4

Location

9.6

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 496 out of 652 reviews
Rating 8 - Good. 111 out of 652 reviews
Rating 6 - Okay. 27 out of 652 reviews
Rating 4 - Poor. 9 out of 652 reviews
Rating 2 - Terrible. 9 out of 652 reviews

Reviews

Verified

10/10 Excellent

Mike

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff, Clean rooms, very pet friendly, couldn't ask for a better place to stay!
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Lynn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, very nice staff, great location
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was substantial and tasty.
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Lorie

Liked: Cleanliness, staff & service
Very convenient location. Clean modern rooms. Comfortable bed. Would stay again.
Stayed 1 night in Feb 2026
Verified

8/10 Good

Stephanie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was amazing and my room was lovely and clean. So convenient to the Sanford Hospital.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was really good! It seemed to use healthier ingredients. The rooms were clean and everyone was very helpful.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Shyanne

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Staff was very friendly, rooms were clean. The stay was amazing
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Tracey

Liked: Cleanliness, staff & service, property conditions & facilities
This is a great hotel - centrally located and very clean and quiet. Will definitely be staying there again.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

jacquelyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location, nice clean property, Starbucks is available if you take a quick walk over the skyway to the hospital. Breakfast was good, wish they offered more fresh fruit or biscuits and gravy, but they had many options for breakfast sandwiches.
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Diane

Liked: Cleanliness, amenities, property conditions & facilities
Staff was very friendly, room was clean
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Kathleen

Liked: Cleanliness, amenities, property conditions & facilities
The room was spotless and the staff was very efficient and personable
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Brandy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Destiny was friendly kind and professional. The room was vey clean and comfortable. I lived my stay.
Stayed 1 night in Mar 2026
Verified

8/10 Good

Stacy

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, staff very helpful.
Stayed 5 nights in Oct 2025
Verified

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
All of it was clean and well maintained
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

claudia

Liked: Cleanliness, amenities, property conditions & facilities
Great hospitality and clean service
Stayed 7 nights in Oct 2025
Verified

10/10 Excellent

Kim

Liked: Cleanliness, property conditions & facilities
The staff was so wonderful! Destynee was so kind, her smile just lifted my spirits. The room was comfortable and spotless. Would definitely stay here again!
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Myla

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and comfortable
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Darrell

Liked: Cleanliness, property conditions & facilities
The room was clean and the place is quiet. It was a nice visit.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Lance

Liked: Cleanliness, amenities, property conditions & facilities
Quiet, clean room
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Katherine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The cleanest hotel I’ve been to. Very quiet and nice.
Stayed 2 nights in Sep 2025
Verified

10/10 Excellent

Stacey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great staff. Great room Will stay again!
Stayed 1 night in May 2025
Verified

10/10 Excellent

Damien

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Only stayed here one night but enjoyed the room and it being connected to the hospital it very convenient. Would definitely stay here again
Stayed 1 night in Jan 2025
Verified

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities
Property was clean and the staff was friendly. Wish there were more dining options in the area.
Stayed 1 night in May 2025
Verified

8/10 Good

Laura

Liked: Amenities, property conditions & facilities
Nice hotel with lots of amenities.
Stayed 1 night in Sep 2024
Verified

8/10 Good

rathmony

Quiet and safe location
Stayed 1 night in Sep 2024