Santiago Vacation Packages for 2025

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

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Santiago Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Hotel & Suites PF

Hotel & Suites PF

3.5 out of 5
Reforma
Save 100% on your flight
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip flight included
Houston (HOU) to Mexico City (MEX)
Stay at this 3.5-star business-friendly aparthotel in Mexico City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Angel of Independence Monument and Paseo de la Reforma are located nearby.

Casa de la Luz Hotel Boutique

Casa de la Luz Hotel Boutique

4 out of 5
Historic Center
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip flight included
Houston (HOU) to Mexico City (MEX)
Stay at this 4-star hotel in Mexico City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Zócalo and Palacio de Bellas Artes are located nearby.

Casa Decu

Casa Decu

4 out of 5
La Condesa
Save 100% on your flight
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip flight included
Houston (HOU) to Mexico City (MEX)
Stay at this 4-star boutique hotel in Mexico City. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Angel of Independence Monument and Paseo de la Reforma are located nearby.

HOTEL LUCA

HOTEL LUCA

4 out of 5
Roma Norte
Save 100% on your flight
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip flight included
Houston (HOU) to Mexico City (MEX)
Stay at this 4-star business-friendly hotel in Mexico City. Enjoy free breakfast, free WiFi, and onsite spa services. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Angel of Independence Monument and Palacio de Bellas Artes are located nearby.

Gran Hotel Ciudad de Mexico Zocalo View

Gran Hotel Ciudad de Mexico Zocalo View

4.5 out of 5
Historic Center
Save 100% on your flight
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip flight included
Houston (HOU) to Mexico City (MEX)
Stay at this 4.5-star luxury hotel in Mexico City. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the restaurant and the helpful staff in our reviews. Popular attractions Zócalo and Palacio de Bellas Artes are located nearby.

Alteza Polanco

Alteza Polanco

4 out of 5
Polanco
Save 100% on your flight
per person
Sep 18 - Sep 23
found 17 hours ago
Roundtrip flight included
Houston (HOU) to Mexico City (MEX)
Stay at this 4-star business-friendly aparthotel in Mexico City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions Paseo de la Reforma and Angel of Independence Monument are located nearby.

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Top Hotel Deals

Hosteria Las Quintas Hotel

Hosteria Las Quintas Hotel

4 out of 5
Avenida Gustavo Diaz Ordaz 9, Colonia Cantarranas, Cuernavaca, MOR
17.27 km from Santiago
Stay at this 4-star eco-certified hotel in Cuernavaca. Enjoy free WiFi, free valet parking, and 3 outdoor pools. Our guests praise the helpful staff and the ...
Hotel Amomoxtli

Hotel Amomoxtli

4 out of 5
Prolongacion Matamoros 115, Barrio Santo Domingo, Valle de Atongo, Tepoztlán, MOR
11.27 km from Santiago
Stay at this 4-star spa hotel in Tepoztlán. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Fiesta Inn Cuernavaca

Fiesta Inn Cuernavaca

3.5 out of 5
Carretera mexico - Acapulco Km 88 S/N, Col. Delicias, Cuernavaca, MOR
15.82 km from Santiago
Stay at this 3.5-star eco-certified hotel in Cuernavaca. Enjoy free WiFi, 2 outdoor pools, and breakfast (surcharge). Our guests praise the helpful staff in ...
Grand Fiesta Americana Sumiya Cuernavaca

Grand Fiesta Americana Sumiya Cuernavaca

4.5 out of 5
Int. Fraccionamiento Sumiya S/N, Col. Jose Parres Jiutepec, Jiutepec, MOR
14.35 km from Santiago
Stay at this 4.5-star luxury hotel in Jiutepec. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property ...
One Cuernavaca

One Cuernavaca

3 out of 5
Carretera Mexico Acapulco KM 88.6 s/n, Cuernavaca, MOR
15.81 km from Santiago
Stay at this 3-star eco-certified hotel in Cuernavaca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Casa Francisco Cuernavaca

Casa Francisco Cuernavaca

4 out of 5
Coronel Ahumada 203, Col. Lomas del Mirador, Cuernavaca, MOR
17.05 km from Santiago
Stay at this 4-star family-friendly hotel in Cuernavaca. Enjoy free parking, 2 outdoor pools, and breakfast (surcharge). Our guests praise the helpful staff ...
Holiday Inn Express Hotel & Suites Cuernavaca by IHG

Holiday Inn Express Hotel & Suites Cuernavaca by IHG

3 out of 5
Avenida Morelos Sur 133, Barrio De Chipitlan, Cuernavaca, MOR
18.24 km from Santiago
Stay at this 3-star business-friendly hotel in Cuernavaca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hotel de Cuautla

Hotel de Cuautla

3 out of 5
No. 114 Batalla 19 de Febrero Centro, Cuautla, MOR
13.54 km from Santiago
Stay at this 3-star business-friendly hotel in Cuautla. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions Six Flags Hurricane Harbor Oaxtepec ...
Fiesta Americana Hacienda San Antonio el Puente Resort & Spa

Fiesta Americana Hacienda San Antonio el Puente Resort & Spa

4 out of 5
Reforma No 2, Real del Puente, Xochitepec, MOR
20.97 km from Santiago
Stay at this 4-star spa hotel in Xochitepec. Enjoy free WiFi, free valet parking, and 2 outdoor pools. Popular attractions St. John the Evangelist Church and ...
Hotel Borda Cuernavaca

Hotel Borda Cuernavaca

3 out of 5
Chulavista 7, Cuernavaca, MOR
19.48 km from Santiago
Stay at this 3-star hotel in Cuernavaca. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Borda Gardens and Museum of the City of ...
Mesón de las Delicias

Mesón de las Delicias

3.5 out of 5
29 Calle General H. Galeana Centro, Cuernavaca, MOR
19.01 km from Santiago
Stay at this 3.5-star hotel in Cuernavaca. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
Posada del Tepozteco - Hotel & Gallery

Posada del Tepozteco - Hotel & Gallery

4 out of 5
Paraiso 3 Barrio San Miguel, Tepoztlán, MOR
11.79 km from Santiago
Stay at this 4-star eco-certified hotel in Tepoztlán. Enjoy free breakfast, free parking, and room service. Our guests praise the helpful staff and the property ...
Hotel Vista Hermosa

Hotel Vista Hermosa

3 out of 5
Rio Panuco 600, Cuernavaca, MOR
17.31 km from Santiago
Stay at this 3-star family-friendly hotel in Cuernavaca. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
Hotel Las Puertas de Tepoztlan

Hotel Las Puertas de Tepoztlan

3.5 out of 5
Calle de la Jardinera #14, Barrio La Santisima Trinidad, Tepoztlán, MOR
12.02 km from Santiago
Stay at this 3.5-star spa hotel in Tepoztlán. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Holiday Inn Cuernavaca by IHG

Holiday Inn Cuernavaca by IHG

3.5 out of 5
Blvd. Diaz Ordaz 86 Col. Acapanzingo, Cuernavaca, MOR
17.44 km from Santiago
Stay at this 3.5-star business-friendly hotel in Cuernavaca. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Volaris
Wed, Oct 29 - Sat, Nov 8
TIJ
General Abelardo L. Rodriguez Intl.
NLU
Felipe Ángeles Intl.
$128 Roundtrip, found 3 days ago
$128
Roundtrip
found 3 days ago
Select Volaris flight, departing Wed, Oct 29 from General Abelardo L. Rodriguez Intl. to Felipe Ángeles Intl., returning Sat, Nov 8, priced at $128 found 3 days ago
Aeromexico
Tue, Nov 11 - Fri, Nov 14
IAH
George Bush Intercontinental
NLU
Felipe Ángeles Intl.
$232 Roundtrip, found 3 days ago
$232
Roundtrip
found 3 days ago
Select Aeromexico flight, departing Tue, Nov 11 from George Bush Intercontinental to Felipe Ángeles Intl., returning Fri, Nov 14, priced at $232 found 3 days ago
Viva
Sat, Aug 16 - Sun, Aug 24
IAH
George Bush Intercontinental
MEX
Mexico City Intl.
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select Viva flight, departing Sat, Aug 16 from George Bush Intercontinental to Mexico City Intl., returning Sun, Aug 24, priced at $259 found 6 days ago
American Airlines
Mon, Sep 29 - Tue, Oct 7
LAX
Los Angeles Intl.
MEX
Mexico City Intl.
$328 Roundtrip, found 6 days ago
$328
Roundtrip
found 6 days ago
Select American Airlines flight, departing Mon, Sep 29 from Los Angeles Intl. to Mexico City Intl., returning Tue, Oct 7, priced at $328 found 6 days ago
Delta
Fri, Sep 26 - Sat, Oct 4
SFO
San Francisco Intl.
MEX
Mexico City Intl.
$349 Roundtrip, found 3 days ago
$349
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Sep 26 from San Francisco Intl. to Mexico City Intl., returning Sat, Oct 4, priced at $349 found 3 days ago