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Comfort Inn and Suites Near Medical Center

2.5 star property
Start your day with a hearty breakfast buffet then dive into relaxation mode by the indoor pool or unwind in style at our serene spa tub.

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Photo gallery for Comfort Inn and Suites Near Medical Center

Exterior - Comfort Inn and Suites Near Medical Center (San Antonio)
2 indoor pools - Comfort Inn and Suites Near Medical Center (San Antonio)
Front of property - Comfort Inn and Suites Near Medical Center (San Antonio)
Standard Room, 1 King Bed | Desk, laptop workspace, iron/ironing board, free WiFi - Comfort Inn and Suites Near Medical Center (San Antonio)
Free daily buffet breakfast - Comfort Inn and Suites Near Medical Center (San Antonio)
Near River Walk, Comfort Inn and Suites Near Medical Center offers a relaxing retreat. Enjoy the free breakfast buffet, unwind in the spa tub or indoor pool, stay connected with in-room WiFi and get some work done at the 24-hour business center. With an ATM on site and laundry services available plus helpful staff that have impressed previous guests.

Reviews

7.4 out of 10
Good

Popular amenities

  • Pool
  • Hot tub
  • Breakfast included
  • Free WiFi
  • Air conditioning

Room options

Available filters for rooms
Showing 6 of 6 rooms

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

Room, 1 King Bed, Accessible, Non Smoking

7.6 out of 10
Good
(10 reviews)
  • 28 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Desk, laptop workspace, iron/ironing board, free WiFi

Room, 2 Queen Beds, Accessible, Non Smoking

  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed

Standard Room, 1 King Bed | Desk, laptop workspace, iron/ironing board, free WiFi

Standard Room, 1 King Bed

7.8 out of 10
Good
(59 reviews)
  • 28 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Desk, laptop workspace, iron/ironing board, free WiFi

Standard Room, 2 Queen Beds

7.4 out of 10
Good
(154 reviews)
  • 28 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed

Suite, 1 King Bed | Desk, laptop workspace, iron/ironing board, free WiFi

Suite, 1 King Bed

7.6 out of 10
Good
(14 reviews)
  • 37 sq m
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Suite, 2 Queen Beds | Desk, laptop workspace, iron/ironing board, free WiFi

Suite, 2 Queen Beds

7.0 out of 10
Good
(60 reviews)
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

About the neighborhood

Located in San Antonio, Comfort Inn and Suites Near Medical Center is near the airport and near a metro station. North Star Mall and Market Square are worth checking out if shopping is on the agenda, while those wishing to experience the area's popular attractions can visit San Antonio Zoo and Aquarium and Six Flags Fiesta Texas. Looking to enjoy an event or a game? See what's going on at Alamodome or Frost Bank Center. Visit our San Antonio travel guide
Map
6039 IH 10 West, Exit #565B-Vance Jackson Rd, San Antonio, TX, 78201

What's nearby

  • River Walk
    River Walk
    8 min drive - 7.0 miles
  • River Walk in San Antonio, Texas
    Lackland Air Force Base
    13 min drive - 14.2 miles
  • Wonderland of the Americas Mall
    1 min drive - 1.4 miles
  • First Unitarian Universalist Church
    1 min drive - 1.9 miles
  • Dellview Park
    2 min drive - 2.4 miles

Getting around

  • San Antonio Station
    16 min drive
  • San Antonio International Airport (SAT)
    9 min drive

Restaurants

  • McDonald's
    16 min walk
  • Taquitos West Avenue
    14 min walk
  • El Pollo Loco
    15 min walk
  • Bill Miller Bar-B-Q
    2 min walk
  • Starbucks
    4 min walk

About this property

Comfort Inn and Suites Near Medical Center

Hotel near River Walk
A free breakfast buffet, a gym, and a 24-hour business center are just a few of the amenities provided at Comfort Inn and Suites Near Medical Center. For some rest and relaxation, visit the hot tub. Stay connected with free in-room WiFi.
Other perks include:
  • 2 indoor pools
  • Free self parking
  • Express check-out, a 24-hour front desk, and a computer station
  • Laundry services, a water dispenser, and smoke-free premises
  • Guest reviews speak highly of the helpful staff
Room features
All 82 rooms feature comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and free newspapers. Guest reviews speak well of the clean rooms at the property.
More conveniences in all rooms include:
  • Bathrooms with rainfall showers and shower/tub combinations
  • 43-inch LED TVs with premium channels
  • Refrigerators, microwaves, and freezers

Similar properties

Front of property
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Medical Center District
  • Pool
  • Hot tub
  • Breakfast included
  • Free WiFi
8.4 out of 10, Very Good, 3,330 reviews
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Free uncovered self parking on site
  • RV/bus/truck parking (surcharge) on site
  • Wheelchair-accessible parking available

Food and drink

  • Free buffet breakfast available 6:00 AM to 9:00 AM on weekdays and 6:00 AM to 9:00 AM on weekends

Things to do

  • 2 indoor pools
  • Gym
  • Hot tub
  • TV in common areas

Family friendly

  • 2 indoor pools
  • In-room microwave
  • In-room refrigerator

Conveniences

  • 24-hour front desk
  • ATM
  • Gift shop/newsstand
  • Vending machine
  • Water dispenser

Guest services

  • Housekeeping (daily)

Business services

  • 24-hour business center
  • Computer station

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel

More

  • 3 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Rainfall showerhead
  • Shampoo
  • Shower/bathtub combination
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 43-inch LED TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Freezer
  • Microwave
  • Refrigerator

More

  • Air conditioning
  • Connecting rooms available
  • Desk
  • Free daily newspapers
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 18

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
This property doesn't offer after-hours check-in
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival
For any questions, please contact the property using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools
This property requires full payment at time of booking the reservation.

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
3 children, up to the age of 17 years, can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Breakage deposit: USD 60 per stay
  • Service fee: USD 4 per accommodation, per night

We have included all charges provided to us by the property.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards, debit cards, and cash
Safety features at this property include a smoke detector, a security system, and window guards
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property

We should mention

Pool access available from 10:00 AM to 10:00 PM
Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 12 years old are not allowed in the swimming pool, fitness facility, or hot tub without adult supervision

Frequently asked questions

Does Comfort Inn and Suites Near Medical Center have a pool?

Yes, this property has 2 Indoor pools. Pool access is from 10:00 AM–10:00 PM.

Is Comfort Inn and Suites Near Medical Center pet-friendly?

No, only service animals are welcome at the property.

How much is parking?

Self parking is free at this property.

What time is check-in at Comfort Inn and Suites Near Medical Center?

Check-in start time: 3 PM; Check-in end time: midnight. After-hours check-in is not available.

What time is check-out at Comfort Inn and Suites Near Medical Center?

Check-out is at 11 AM.

Where is Comfort Inn and Suites Near Medical Center located?

Situated near the airport, this hotel is 1.2 mi (2 km) from Wonderland of the Americas Mall and 1.2 mi (2 km) from Methodist Hospital Texsan. River Walk and San Antonio Zoo and Aquarium are also within 6 mi (10 km).

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Comfort Inn and Suites Near Medical Center Reviews

7.4

Good

7.0

Cleanliness

7.0

Amenities

7.2

Staff & service

7.0

Property conditions & facilities
Rating 10 - Excellent. 851 out of 2042 reviews
Rating 8 - Good. 358 out of 2042 reviews
Rating 6 - Okay. 300 out of 2042 reviews
Rating 4 - Poor. 240 out of 2042 reviews
Rating 2 - Terrible. 293 out of 2042 reviews

Reviews

Verified

10/10 Excellent

Diana

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room, great spot and super affordable
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
very clean, staff was helpful and friendly, will stay again pool was clean and open! breakfast had big variety as well.
Stayed 3 nights in Apr 2026
Verified

10/10 Excellent

Gilbert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean and breakfast was a good morning start
Stayed 1 night in Mar 2026
Verified

8/10 Good

Tim

Liked: Cleanliness, staff & service, property conditions & facilities
Didn't try the breakfast, parking feels safe and convenient.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Jerry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The rooms were very clean and the beds were really comfortable. The price was fair for the size room we stayed in. We will be staying again next time we are in town.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Stevan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly rooms were clean and comfy, showers on the other hand need to be replaced
Stayed 1 night in Apr 2026
Verified

8/10 Good

Robert

Liked: Cleanliness, amenities, property conditions & facilities
Good location, clean room, good price
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Hiren

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
All is good
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Jose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very clean and even smelled clean
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Dina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Yes breakfast 😋
Stayed 1 night in Mar 2026
Verified

8/10 Good

Christina

Liked: Cleanliness, amenities, property conditions & facilities
Room was updated recently and was very clean....staff was very nice.
Stayed 3 nights in Feb 2026
Verified

6/10 Okay

Joni

Liked: Staff & service
Disliked: Amenities
If you’re looking for an affordable place to stay while exploring San Antonio, this hotel gets the job done. The location is super convenient—close to downtown, the Riverwalk, and right next to Walmart, which made grabbing essentials really easy. One downside: housekeeping didn’t come to clean the room at all until the very last day, which was a bit disappointing. Overall, I’d rate it a solid 3/5—great for budget travelers who care more about location than full service.
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Eugene

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Clean throughout, very good breakfast, friendly and efficient staff.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Ana

Liked: Cleanliness, staff & service, amenities
Excellent location and excellent services.
Stayed 2 nights in Nov 2025
Verified

6/10 Okay

Brandon

Liked: Staff & service, amenities, property conditions & facilities
VERY, VERY thin walls. You could hear every conversation in the hallway from your room and vice versa. Cleanliness was pretty good and had no issues with staff or other people there.
Stayed 1 night in Apr 2026
Verified

6/10 Okay

Brian

Liked: Staff & service, amenities
Disliked: Cleanliness
Room was pretty comfortable but the lobby and elevator reeked of weed. Staff was nice and helpful and breakfast was pretty good.
Stayed 1 night in Feb 2026
Verified

4/10 Poor

Sylvia Z

Disliked: Amenities, property conditions & facilities
Facility overall reception area clean ... room was very musty ... humid smell. Overall not a good stay ... do not recommend.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy & secure parking. Friendly staff & pleased with the room & reasonable price.
Convenient restaurant literally 2 minute walk, enjoyed takeout to my room.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Linda

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, nice staff, I enjoy restarting here every time Im in San Antonio
Stayed 1 night in Dec 2025
Verified

8/10 Good

Vicente

Liked: Cleanliness, amenities, property conditions & facilities
Very nice hotel,great location ( right next to an ihop), very friendly staff! The breakfast bar was okay our eggs and sausage ended up being cold but there’s a microwave in the area that can be used just may have a small wait time depending on how many guest are in the cafe area but over all had a great experience and would definitely stay here again!
Stayed 2 nights in Jan 2026
Verified

8/10 Good

Brandy

Liked: Cleanliness
Clean, quiet, good breakfast. Indoor pool and hot tub nice but pool needed cleaning or chemicals, murky, couldnt see the bottom...so i didnt get in. Hot tub was clean.
Stayed 1 night in Mar 2026
Verified

6/10 Okay

Russell

Liked: Staff & service
It wasn’t as clean as the pics make it seem. Every room is very humid, and there’s mold and stains everywhere. Breakfast was decent though.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Jesse

Liked: Cleanliness, staff & service, amenities
The ac worked very well. Was able to check in a before the time.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Ayriana

Liked: Cleanliness, staff & service, property conditions & facilities
Staff was really friendly ! Thanks to Vaish 🙌
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Destini

Liked: Cleanliness, staff & service, amenities
Room was kept up with daily. Breakfast was always great and fast.
Stayed 8 nights in Dec 2025