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Serena Hotel

3.0 star property
Guests savor authentic Italian breakfast before stepping out to explore Rome's ancient ruins, with express check-in and multilingual staff ready to assist

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Photo gallery for Serena Hotel

A hotel entrance with a sign reading "HOTEL SERPENTINE HOTEL." - Serena Hotel (Rome)
A hotel room with a large bed, a wooden wardrobe, a desk with a mirror, and a view of buildings through the window. - Serena Hotel (Rome)
A reception desk with a chandelier, multiple wall clocks, and framed documents. - Serena Hotel (Rome)
Reception - Serena Hotel (Rome)
A hotel dining area with round tables covered in yellow tablecloths and red curtains. - Serena Hotel (Rome)
Serena Hotel in Rome's historic center offers local breakfast specialties to start your day right. Unwind at the cozy bar, stay connected with in-room WiFi, and save sightseeing time with express check-in/out. The helpful multilingual staff consistently impresses visitors.

Reviews

7.8 out of 10
Good

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Bar
  • Housekeeping

Room options

Available filters for rooms
Showing 3 of 3 rooms

View all photos for Single Room

A hotel room with a bed, a desk with a mirror, and a chair.

Single Room

8.4 out of 10
Very good
(29 reviews)
  • 15 sq m
  • Sleeps 1
  • 1 Twin Bed
  • Free WiFi

View all photos for Double Room

Minibar, in-room safe, desk, free WiFi

Double Room

8.0 out of 10
Very good
(26 reviews)
  • 17 sq m
  • Sleeps 3
  • 1 Double Bed OR 2 Twin Beds
  • Free WiFi

View all photos for Triple Room

Minibar, in-room safe, desk, free WiFi

Triple Room

7.6 out of 10
Good
(5 reviews)
  • 19 sq m
  • Sleeps 3
  • 3 Twin Beds
  • Free WiFi

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About the neighborhood

Located in Rome City Centre, a neighborhood in Rome, Serena Hotel is near a metro station. Colosseum and Trevi Fountain are notable landmarks, and travelers looking to shop may want to visit Via Veneto and Via del Corso. Looking to enjoy an event or a game? See what's going on at Foro Italico or Stadio Olimpico. Visit our Rome travel guide
Map
Via Principe Amedeo 64, Rome, RM, 00185

What's nearby

  • A nighttime outdoor café with tables and umbrellas, surrounded by cobblestone streets and historic buildings.
    Piazza Santa Maria Maggiore
    3 min walk - 0.2 miles
  • A historic building with a clock tower and statues, surrounded by pigeons.
    Basilica di Santa Maria Maggiore
    3 min walk - 0.2 miles
  • A nighttime view of a grand fountain with statues in front of a large, illuminated building.
    Piazza della Repubblica
    6 min walk - 0.4 miles
  • A row of colorful buildings with ornate facades and shutters.
    Via Nazionale
    6 min walk - 0.4 miles
  • Teatro dell'Opera di Roma
    5 min walk - 0.3 miles

Getting around

  • Farini Tram Stop
    2 min walk
  • Rome Termini Station
    4 min walk
  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO)
    45 min drive

Restaurants

  • Trattoria Pizzeria Angelo
    1 min walk
  • KFC
    2 min walk
  • Osteria Santa Maria Romana
    3 min walk
  • Da Tudini 1969
    2 min walk
  • Ristorante Elettra
    1 min walk

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • No onsite parking available

Food and drink

  • Free local cuisine breakfast available daily 7:30 AM to 10:00 AM
  • A bar/lounge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Luggage storage
  • Safe at front desk

Guest services

  • Housekeeping (daily)
  • Multilingual staff
  • Tour and ticket assistance

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)

More

  • 1 building
  • 4 floors
  • Reception hall
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Hair dryer
  • Towels provided

Entertainment

  • Flat-screen TV with satellite channels

Food and drink

  • Minibar

More

  • Air conditioning (climate-controlled)
  • Desk
  • Safe

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: midnight
Express check-in available

Check-out

Check-out before 10:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Guests must contact the property in advance for check-in instructions; front desk staff will greet guests on arrival at the property
To make arrangements for check-in please contact the property ahead of time using the information on the booking confirmation
If you are planning to arrive after midnight please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets stay free
Service animals are welcome, and are exempt from fees
Food and water bowls are available

Children and extra beds

Children are welcome
Children up to the age of 8 years can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • A tax is imposed by the city: EUR 6.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

We have included all charges provided to us by the property.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and a first aid kit

We should mention

All guests, including children, must be present at check-in and show their government-issued photo ID card or passport
Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using information in the booking confirmation

National rating

This property has received its official star rating from the local rating authority.

Frequently asked questions

Is Serena Hotel pet-friendly?

Yes, pets are allowed at this property.

How much is parking?

Serena Hotel doesn't offer parking.

What time is check-in at Serena Hotel?

Check-in start time: 2:00 PM; Check-in end time: midnight.

What time is check-out at Serena Hotel?

Check-out is at 10:00 AM.

Where is Serena Hotel located?

Located in Rome City Centre, this hotel is within a 10-minute walk of Piazza Santa Maria Maggiore and Via Nazionale. Colosseum and Trevi Fountain are also within 1 mi (2 km). Farini Tram Stop and Termini Tram Stop are within a 5-minute walk.

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Reviews

Serena Hotel Reviews

7.8

Good

8.2

Cleanliness

8.0

Location

8.2

Staff & service

7.4

Property conditions & facilities
Rating 10 - Excellent. 236 out of 768 reviews
Rating 8 - Good. 311 out of 768 reviews
Rating 6 - Okay. 149 out of 768 reviews
Rating 4 - Poor. 40 out of 768 reviews
Rating 2 - Terrible. 32 out of 768 reviews

Reviews

Verified

10/10 Excellent

Mina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful place to stay while in Rome, rooms are clean and very old fashioned, yet equipment with everything you might need. All the big attractions are close by and easy to walk to or access by bus. And most importantly the staff are super friendly and helpful. I would recommend it and I will definitely stay here again whenever I came back to Rome!
Stayed 3 nights in Jun 2026
Verified

6/10 Okay

Silvia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location close to the train station.Found room quite small and dark though.Breakfast was just ok.Good for a short stay.
Stayed 2 nights in Jun 2026
Verified

8/10 Good

Patricia

Liked: Cleanliness, staff & service, property conditions & facilities
Disliked: Amenities
Check-in was very quick. The room was comfortable. Close to lots of restaurants.
Stayed 1 night in May 2026
Verified

6/10 Okay

Elee

Liked: Cleanliness
Disliked: Amenities
The good - convenient location to Rome Termini station, shops, cafes outside. The not-so-good - AC took forever to cool, staff not so friendly, dark room.
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Erika

Liked: Cleanliness, staff & service, property conditions & facilities
Our breakfast was fresh, good coffee, good service and clean, super close to the train station and shops.
Stayed 3 nights in Apr 2026
Verified

10/10 Excellent

veronica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Marco was very nice and helpful. Walking distance to Termini station. Great selection of food by the Termini.
Stayed 5 nights in May 2026
Verified

10/10 Excellent

Stepan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was ver good and the staff freiendly
Stayed 6 nights in Mar 2026
Verified

10/10 Excellent

Lena

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
A hidden gem. I booked this hotel as it was an easy walk from Roma Termini and just as close to the Basilica St Maria Maggiore. It's situated on a side street so little traffic. There's a selection of reasonably priced restaurants and amazingly a launderette almost next to the hotel, it does service wash and dry very quickly. The staff at the hotel are welcoming and helpful. Good size room, comfortable and quiet at night. I'd certainly book this again.
Stayed 1 night in Jun 2026
Verified

8/10 Good

Livier

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We arrived in the morning after an 10 hour flight and luckily our room was ready and the man in the front was super helpful. The room were basic and old but not bad. Bed was hard but after walking 20k steps a day it didn’t matter. Breakfast was small but good, no big American pancakes or waffles but lots of good pastries, fruits, yogurt, juices, and coffee. Great location.
Stayed 5 nights in Apr 2026
Verified

10/10 Excellent

Eangelica

Liked: Cleanliness, staff & service, property conditions & facilities
Great staff even during Christmas holidays - easy arrival and checkout and friendly team at work.
Stayed 3 nights in Dec 2025
Verified

6/10 Okay

Andrew

Liked: Cleanliness, staff & service
Disliked: Amenities
Good location for getting everywhere. Staff very friendly. Charming old fashioned lift. Single room small and a bit basic. safe didn't work. Breakfast ok though not very distinguished
Stayed 3 nights in Apr 2026
Verified

8/10 Good

Malena

Liked: Staff & service, property conditions & facilities
Super nice staff and great breakfast!! Very convenient location.
Stayed 3 nights in Oct 2025
Verified

8/10 Good

Barry

Liked: Cleanliness, staff & service
Room was clean. Great location to train station. Breakfast was ok. AC did not work. Very hot. Had to sleep with the windows open. Street noise all night is very loud. Can be a troublesome area.
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Snowden

Liked: Cleanliness, staff & service, amenities
clean room. friendly staff.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Monica

Liked: Cleanliness, staff & service, property conditions & facilities
Great location and staff at the hotel v
Stayed 3 nights in Apr 2025
Verified

8/10 Good

Rodolfo

Liked: Property conditions & facilities
Central located and a lot of facilities around. The personal were friendly and helpful. The cleaning at the bathroom could be better. looking up at the top parts would be a good tip for the cleaners.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Gary

Liked: Cleanliness, amenities, property conditions & facilities
Great room. No issues with check in.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Carol

Liked: Cleanliness, staff & service, amenities
Staff very nice and courtious. Room was cleaned every day. Nice breakfast.
Stayed 4 nights in Nov 2025
Verified

10/10 Excellent

Paul

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was friendly and it was in a great location 👍
Stayed 5 nights in Mar 2025
Verified

10/10 Excellent

Neil

Smooth check-in, clean room.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Eric

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location and staff
Stayed 5 nights in May 2024
Verified

10/10 Excellent

Karen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love the location very friendly and helpful staff Room is clean Thanks again Hetel Serena!!
Stayed 2 nights in May 2025
Verified

10/10 Excellent

Chelsea

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
GOOD LOCATION, STAFF VERY FRIENDLY AND HELPFUL!
Stayed 1 night in Mar 2025
Verified

8/10 Good

hanna

Liked: Staff & service, property conditions & facilities
Very good
Stayed 1 night in Nov 2025
Verified

8/10 Good

Serena

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very close to Roma Termini with lots of restaurants on the same street. Hotel breakfast was really good! Bed abit hard but clean room.
Stayed 3 nights in Sep 2025