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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
Hotel with free breakfast, a short walk to Duke University

Choose dates to view prices

Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

Courtyard
Exterior
Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace
Lobby
Full-size fridge, microwave, stovetop, dishwasher
Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Bar
  • Kitchen
  • Parking available
  • Pet friendly

Room options

Check availability for these dates

Tonight

Sep 25 - Sep 26
Check availability for tonight Sep 25 - Sep 26

Tomorrow

Sep 26 - Sep 27
Check availability for tomorrow Sep 26 - Sep 27
Available filters for rooms
Showing 10 of 10 rooms

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 44 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 44 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking

8.8 out of 10
Excellent
(31 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(14 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 39 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized refrigerator/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 40 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

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About the neighborhood

Located in Downtown Durham, a neighborhood in Durham, Residence Inn Durham McPherson/Duke University Medical Cntr is near a train station. Sarah P. Duke Gardens and Museum of Life and Science are local attractions and those in the mood for shopping can visit Brightleaf Square and Northgate Mall. Looking to enjoy an event or a game while in town? See what's happening at Pauli Murray Center for History and Social Justice or Durham Bulls Athletic Park.
Visit our Durham travel guideOpens in a new window
Map
1108 West Main Street, Durham, NC, 27701

What's nearby

  • Duke University - 3 min walk - 0.2 miles
  • Durham Bulls Athletic Park - 16 min walk - 0.9 miles
  • Durham Performing Arts Center - 17 min walk - 0.9 miles
  • Duke University Hospital - 2 min drive - 1.7 miles
  • Cameron Indoor Stadium - 6 min drive - 2.5 miles

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

  • ‪The Can Opener - ‬7 min walk
  • ‪Fonda Lupita - ‬3 min walk
  • ‪Ramblers - ‬7 min walk
  • ‪Emmy Squared - ‬5 min walk
  • ‪The Federal - ‬3 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel remodeled in 2024 and located near Duke University
Consider a stay at Residence Inn Durham McPherson/Duke University Medical Cntr and take advantage of free to-go breakfast, a free grocery shopping service, and a terrace. In addition to dry cleaning/laundry services and a fireplace in the lobby, guests can connect to free in-room WiFi.
Other perks include:
  • A free area shuttle, self parking (surcharge), and express check-out
  • Express check-in, a banquet hall, and concierge services
  • Luggage storage, a computer station, and a 24-hour front desk
  • Guest reviews speak highly of the helpful staff
Room features
All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches like free WiFi and desk chairs.
Extra conveniences in all rooms include:
  • Recycling and LED light bulbs
  • Shower/tub combinations, free toiletries, and hair dryers
  • 32-inch Smart TVs with Netflix and premium channels
  • Wardrobes/closets, separate sitting areas, and kitchens

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • A bar/lounge
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business center
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2015
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 100 lbs per pet)
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Optional extras

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?

Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 100 lbs per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much is parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Self parking is available for USD 15 per day.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; Check-in end time: midnight.

What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-out is at noon.

Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?

Located in Downtown Durham, this hotel is within a 10-minute walk of Brightleaf Square and Duke University. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.

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Reviews

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

9.2

Wonderful

9.4

Cleanliness

9.0

Location

9.4

Staff & service

9.0

Eco-friendliness

9.4

Property conditions & facilities
Rating 10 - Excellent. 306 out of 446 reviews
Rating 8 - Good. 101 out of 446 reviews
Rating 6 - Okay. 25 out of 446 reviews
Rating 4 - Poor. 6 out of 446 reviews
Rating 2 - Terrible. 8 out of 446 reviews

Reviews

10/10 Excellent

Derek

Liked: Cleanliness, staff & service, property conditions & facilities
Was very nice. The staff was very polite when we arrived.
Stayed 1 night in Aug 2025

8/10 Good

Maria

Liked: Cleanliness, staff & service, amenities
Great location! You can walk to great restaurants and coffee shops. The room is clean and spacious. The bed is very comfortable and it felt like a nice treat at the end of long day. The staff is very friendly, specially Tiffani and Laura at the reception desk. They were very helpful and welcoming, always greeting you with a big smile and making sure we were doing fine. I will definitely stay there on my next visit.
Stayed 7 nights in Aug 2025

8/10 Good

Heman

Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was amazing! Breakfast had so many options, quiche, waffles, fresh fruit, sausage, hard boiled eggs…. Room was very clean. Small market store in lobby. Lobby area with a tv and tons of seating. Nice workout room. But again, staff was incredible!
Stayed 8 nights in Jul 2025

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025

10/10 Excellent

Kaiqing

Liked: Cleanliness, staff & service, property conditions & facilities
All good as expected
Stayed 14 nights in Jul 2025

10/10 Excellent

Ronnie A.

Liked: Cleanliness, staff & service, property conditions & facilities
We had an issue with the room but the district manager took care of it immediately. Excellent Team
Stayed 8 nights in Jul 2025

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025

8/10 Good

Minor

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.
Stayed 7 nights in May 2025

10/10 Excellent

Reed

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.
Stayed 6 nights in Apr 2025

10/10 Excellent

Judy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location with some incredible Restaurants nearby
Stayed 3 nights in Oct 2024

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025

8/10 Good

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Shoutout to Tiffany/Stephanie? on front desk duty - she greeted us with a warm welcome & useful information!
Stayed 1 night in May 2025

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great and reasonably priced place to stay as a family in the center of Durham.
Stayed 1 night in Sep 2024

6/10 Okay

Tian

Disliked: Staff & service, amenities
It smelled musky and like urine in our room and much of the facility just smelled like cleaning supplies. The wifi wasn’t great in the room. The location is decently close to Duke, but the immediate area is at a street intersection right by a gas station. There was plenty of parking for pay by mobile 15$.
Stayed 1 night in May 2025

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great value, good location, decent breakfast

Clean, walking distance to gas stations and restaurants.,, decent breakfast in the morning that was free so can't complain... free hot coffee all day... spacious and well-decorated rooms with good cable and smart tvs. All around, great value for the price
Stayed 2 nights in Jan 2025

10/10 Excellent

Swarup

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stuffs are nice!
Stayed 1 night in Dec 2024

10/10 Excellent

Jo Anne

Liked: Cleanliness, staff & service, property conditions & facilities
Great place
Stayed 2 nights in May 2024

10/10 Excellent

Christopher

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place!
Stayed 3 nights in Dec 2023

10/10 Excellent

Cynthia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Loved Tiffani. Beautiful facility.

The hotel was beautiful, conveniently octane the suite was immaculate. The receptionist,Tiffani, was kind and charming, a great representative of your company.
Stayed 1 night in Dec 2024

4/10 Poor

zubina

Disliked: Amenities, property conditions & facilities
Close to campus Convenient breakfast Old facility Convenient parking
Stayed 2 nights in Aug 2024

10/10 Excellent

eric

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

The place to stay!!

A very clean and quiet hotel property with great breakfast in the morning. Ample parking and reasonably priced. All of the staff were very friendly. Would definitely recommend.
Stayed 2 nights in Oct 2024

10/10 Excellent

Lalita

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Excellent

Loved how clean and big the room was.
Stayed 3 nights in Aug 2024

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