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The Chemists’ Club Hotel

4.0 star property
A boutique retreat from Manhattan's bustle awaits near Grand Central Terminal, where travelers find respite from the city's energy

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Deluxe Room, 1 Queen Bed, Terrace | Down comforters, in-room safe, desk, laptop workspace - The Chemists’ Club Hotel (New York)
Fitness facility - The Chemists’ Club Hotel (New York)
Exterior - The Chemists’ Club Hotel (New York)
Restaurant - The Chemists’ Club Hotel (New York)
Interior - The Chemists’ Club Hotel (New York)
The Dylan Hotel NYC offers a peaceful Midtown haven steps from Bryant Park and the Empire State Building. Guests can work out in the 24-hour gym, dine at the restaurant, or relax with drinks at the bar. Free in-room WiFi and multilingual staff make guests feel at home.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Free WiFi
  • Restaurant
  • Air conditioning
  • Bar
  • Laundry

Room options

Available filters for rooms
Showing 11 of 11 rooms

View all photos for Classic Room, 1 King Bed

Down comforters, in-room safe, desk, laptop workspace

Classic Room, 1 King Bed

9.8 out of 10
Exceptional
(18 reviews)
  • 19 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Deluxe Room, 1 King Bed

Down comforters, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

9.4 out of 10
Exceptional
(46 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Deluxe Room, 1 Queen Bed

Deluxe Room, 1 Queen Bed | Down comforters, in-room safe, desk, laptop workspace

Deluxe Room, 1 Queen Bed

10.0 out of 10
Exceptional
(1 review)
  • 19 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free WiFi

View all photos for Deluxe Room, 2 Double Beds

Deluxe Room, 2 Double Beds | Down comforters, in-room safe, desk, laptop workspace

Deluxe Room, 2 Double Beds

10.0 out of 10
Exceptional
(3 reviews)
  • 33 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free WiFi

View all photos for Deluxe Double Mobility/Hearing Accessible with Roll-In Shower

Down comforters, in-room safe, desk, laptop workspace

Deluxe Double Mobility/Hearing Accessible with Roll-In Shower

10.0 out of 10
Exceptional
(3 reviews)
  • 33 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free WiFi

View all photos for King Deluxe Mobility/Hearing Accessible with Roll-In Shower

Down comforters, in-room safe, desk, laptop workspace

King Deluxe Mobility/Hearing Accessible with Roll-In Shower

10.0 out of 10
Exceptional
(1 review)
  • 33 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for Junior Suite

Down comforters, in-room safe, desk, laptop workspace

Junior Suite

8.8 out of 10
Excellent
(8 reviews)
  • 37 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Deluxe Room, 1 Queen Bed, Terrace

Deluxe Room, 1 Queen Bed, Terrace | Down comforters, in-room safe, desk, laptop workspace

Deluxe Room, 1 Queen Bed, Terrace

  • 19 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Queen Bed
  • Free WiFi

View all photos for Junior Suite King Mobility/Hearing Accessible with Transfer Shower

Down comforters, in-room safe, desk, laptop workspace

Junior Suite King Mobility/Hearing Accessible with Transfer Shower

  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Alchemy Suite

Alchemy Suite | Down comforters, in-room safe, desk, laptop workspace

Alchemy Suite

10.0 out of 10
Exceptional
(1 review)
  • 33 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

View all photos for King Deluxe Mobility/Hearing Accessible with Tub

Down comforters, in-room safe, desk, laptop workspace

King Deluxe Mobility/Hearing Accessible with Tub

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

About the neighborhood

Located in Manhattan, a neighborhood in New York, The Chemists’ Club Hotel is near a metro station. Manhattan Cruise Terminal and South Street Seaport are worth checking out if an activity is on the agenda, while those wishing to experience the area's popular attractions can visit Lincoln Center and Chelsea Piers. American Museum of Natural History and American Dream are not to be missed. Take an opportunity to explore the area for outdoor excitement like hiking/biking trails and other activities like ice skating. Visit our New York travel guide
Map
52 E 41st St, New York, NY, 10017

What's nearby

  • A busy urban street with pedestrians, cars, and a large American flag.
    5th Avenue
    3 min walk - 0.2 miles
  • A historic building with ornate architecture and a modern glass skyscraper in the background.
    Grand Central Terminal
    3 min walk - 0.2 miles
  • A park with green trees and grass, surrounded by tall buildings.
    Bryant Park
    5 min walk - 0.3 miles
  • A tall, beige skyscraper with many windows, surrounded by palm trees and other buildings.
    Rockefeller Center
    9 min walk - 0.5 miles
  • Times Square with large billboards and skyscrapers.
    Times Square
    11 min walk - 0.6 miles

Getting around

  • Grand Central - 42 St. Station
    2 min walk
  • 5 Av Station (W. 42nd St.)
    4 min walk
  • LaGuardia Airport (LGA)
    26 min drive

Restaurants

  • Après
    3 min walk
  • Chick-fil-A
    2 min walk
  • Pershing Square
    2 min walk
  • Los Tacos No. 1
    2 min walk
  • Tartinery Café - Bar | Park Ave
    2 min walk

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Offsite parking within 0.2 miles (USD 65 per day)

Food and drink

  • A bar/lounge
  • A restaurant

Things to do

  • 24-hour gym

Family friendly

  • In-room crib
  • In-room refrigerator
  • Laundry facilities
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Tour and ticket assistance

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Elevator
  • Wheelchair accessible (may have limitations)

More

  • 16 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Down comforter
  • Free crib

Bathroom

  • Bathrobes
  • Bathtub or shower
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Slippers
  • Towels provided

Entertainment

  • 55-inch LED TV with cable channels

Food and drink

  • Coffee/tea maker
  • Electric kettle
  • Limited room service
  • Refrigerator

More

  • Air conditioning
  • Desk
  • Desk chair
  • Free weekday newspapers
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • Phone
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: anytime
Early check-in subject to availability
Early check-in fee: USD 60.00
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Late check-out subject to availability
Late check-out fee: USD 150

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
10 children, up to the age of 1, can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Deposit: USD 50.00 per night
  • Destination fee: USD 40.17 per accommodation, per night

We have included all charges provided to us by the property.

Optional extras

  • Offsite parking fee: USD 65 per day (0.2 mi away)
  • Early check-in fee: USD 60.00 (subject to availability)
  • Late check-out fee: USD 150 (subject to availability)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
Guests must contact this property in advance to reserve cribs/infant beds
This property accepts credit cards and cash
Noise-free guestrooms cannot be guaranteed
Safety features at this property include a fire extinguisher

We should mention

This property's policy is to refuse certain bookings for the purpose of group events or parties, including pre-wedding stag/bachelor and hen/bachelorette parties
Only registered guests are allowed in the guestrooms
A car is not required for transportation to and from this property
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Is The Chemists’ Club Hotel pet-friendly?

No, only service animals are welcome at the property.

What time is check-in at The Chemists’ Club Hotel?

Check-in start time: 3 PM; Check-in end time: anytime. Early check-in is available for a fee of USD 60.00 (subject to availability).

What time is check-out at The Chemists’ Club Hotel?

Check-out is at 11 AM. Late check-out is available for USD 150 (subject to availability).

Where is The Chemists’ Club Hotel located?

Located in Manhattan, this boutique hotel is within a 5-minute walk of Grand Central Terminal and 5th Avenue. Bryant Park and Rockefeller Center are also within 10 minutes. Grand Central - 42 St. Station is only a 2-minute walk and 5 Av Station (W. 42nd St.) is 4 minutes.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

The Chemists’ Club Hotel Reviews

9.4

Exceptional

9.8

Cleanliness

9.4

Amenities

9.6

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 354 out of 445 reviews
Rating 8 - Good. 62 out of 445 reviews
Rating 6 - Okay. 17 out of 445 reviews
Rating 4 - Poor. 5 out of 445 reviews
Rating 2 - Terrible. 7 out of 445 reviews

Reviews

Verified

10/10 Excellent

Elizabeth

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was very welcoming and the room was very clean. It’s in a great location, and we’ll definitely be back.
Stayed 4 nights in Jun 2026
Verified

10/10 Excellent

Carly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean room; staff was super nice and helpful.
Stayed 3 nights in May 2026
Verified

10/10 Excellent

Vaheid

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Friendly staff, clean facility, nice gym and good location
Stayed 3 nights in May 2026
Verified

10/10 Excellent

eden

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is a lovely boutique hotel centrally located. I could go on and on about how wonderful all the employees are here, so welcoming, and efficient. We have stayed twice, and always leave happy.
Stayed 1 night in May 2026
Verified

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fabulous staff and unbeatable location right down from the NY Public Library. We loved it!
Stayed 3 nights in May 2026
Verified

10/10 Excellent

John

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean and beautiful property. Pleasant staff
Stayed 2 nights in May 2026
Verified

10/10 Excellent

Sharon

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely hotel in great location. Room was rather small and no room service. Staff is the best. Will stay there again.
Stayed 5 nights in May 2026
Verified

10/10 Excellent

Beverly

Liked: Cleanliness, staff & service, property conditions & facilities
Wonderful stay - lovely hotel, comfortable room, pleasant staff, quiet and cozy
Stayed 3 nights in Apr 2026
Verified

10/10 Excellent

Brandon

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stayed at Chemists Club NYC and had a great experience. The staff was excellent — friendly, helpful, and made us feel welcome throughout our stay. The hotel was very clean and well kept, which really stood out. The location is also fantastic and made it easy to get around and explore the city. Overall, a great place to stay in NYC and I’d definitely recommend it!
Stayed 4 nights in May 2026
Verified

10/10 Excellent

Nadine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff of this hotel is dedicated to making your stay as fantastic as possible. Thank you for a wonderful service!
Stayed 2 nights in May 2026
Verified

10/10 Excellent

Jorge

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing stay! Staff was super friendly and helpful, hotel is cute and location is the best. Room was quaint, clean and comfortable, bathroom was on the smaller side but that’s to be expected from NYC. Great place, will surely comeback.
Stayed 6 nights in Apr 2026
Verified

10/10 Excellent

William

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Spectacular. Most good hotel stays I can come up with a few things I'd change/fix; here: nothing. Super clean, well-laid out room with a high ceilings, great bathroom, great shower. And the chemistry nerd theme was perfect.
Stayed 2 nights in May 2026
Verified

10/10 Excellent

Roya

Liked: Cleanliness, amenities, property conditions & facilities
Wonderful hotel and bedding was so comfortable!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Andrew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing hotel. Clean, comfortable, and great service. Staff was lovely.
Stayed 5 nights in Mar 2026
Verified

10/10 Excellent

Rachel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean large room Friendly staff
Stayed 4 nights in Mar 2026
Verified

10/10 Excellent

Sabrina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
That’s my second time staying with them am I can definitely say it is my favorite hotel. Staff is very friendly and accommodating. Room is amazing and the amenities are great!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Claudian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing and professional staff, very warm and helpful, gorgeous rooms and lobby. Very high ceilings and big windows. GREAT location just steps away from grand central
Stayed 1 night in Mar 2026
Verified

8/10 Good

Peter

Liked: Cleanliness, staff & service, amenities
Great location and big rooms
Stayed 5 nights in Jan 2026
Verified

10/10 Excellent

Tamara Jane de

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Front desk was super accommodating - early check in and late check out! The bellhops were super friendly and helpful. Would definitely come back :)
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Greg

Liked: Cleanliness, amenities, property conditions & facilities
very clean hotel. excellent location
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Heather

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was very clean and updated. Staff was exceptional! Check in was seamless and accommodating. The beds were comfortable and quiet. We stayed for 3 nights for a mother/son trip. Close to Grand Central which provided easy access to subway. I would definitely stay again.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Trish

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was great with fast service. The rooms were spacious and clean. The location was excellent. The staff were FANTASTIC! Next time I am in town, I will come back to the Chemists' Club. Thank you for taking care of me and my family.
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Lisa

Liked: Cleanliness, amenities, property conditions & facilities
Nice room, helpful staff, great location, we loved it!
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Shira

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice and clean room
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Robert

Liked: Cleanliness, amenities, property conditions & facilities
Great location and staff!
Stayed 2 nights in Dec 2025