
Lower Keys Vacation Packages for 2025
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Lower Keys Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.

Oceans Edge Key West Resort, Hotel & Marina
Save 100% on your flight
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Key West (EYW)
Stay at this 4-star luxury hotel in Key West. Enjoy free WiFi, 6 outdoor pools, and a marina. Our guests praise the pool and the restaurant in our reviews. Popular attractions Duval Street and Smathers Beach are located nearby.

Winslow's Bungalows - Key West Historic Inns
Old Town Key West
Save 100% on your flight
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Key West (EYW)
Stay at this 4-star hotel in Key West. Enjoy free breakfast, free WiFi, and 3 outdoor pools. Our guests praise the breakfast and the pool in our reviews. Popular attractions Duval Street and Ernest Hemingway Home and Museum are located nearby.

Lighthouse Hotel - Key West Historic Inns
Old Town Key West
Save 100% on your flight
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Key West (EYW)
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Duval Street and Ernest Hemingway Home and Museum are located nearby.

Orchid Key Inn - Adults Only
Old Town Key West
Save 100% on your flight
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Key West (EYW)
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular attractions Duval Street and Ernest Hemingway Home and Museum are located nearby.

Ella's Cottages - Key West Historic Inns
Old Town Key West
Save 100% on your flight
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Key West (EYW)
Stay at this 3.5-star business-friendly hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Duval Street and Ernest Hemingway Home and Museum are located nearby.

Ridley House - Key West Historic Inns
Key West Historic District
Save 100% on your flight
per person
Aug 20 - Aug 25
found 1 day ago
Roundtrip non-stop flight included
Myrtle Beach (MYR) to Key West (EYW)
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Duval Street and Mallory Square are located nearby.
Top Hotel Deals

Looe Key Reef Resort
27340 Overseas Highway, Summerland Key, FL
9.13 km from city center
Stay at this hotel in Summerland Key. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the bar and the helpful staff in our reviews. ...

Sugarloaf Key Hotel at KOA Resort
251 Co Rd 939, Summerland Key, FL
3.36 km from city center
Stay at this 3-star hotel in Summerland Key. Enjoy free WiFi, free parking, and a private beach. Our guests praise the helpful staff and the clean rooms in our ...

Old Wooden Bridge Resort and Marina
1791 Bogie Drive, Big Pine Key, FL
14.91 km from city center
Stay at this cottage in Big Pine Key. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Blue ...

Parmer's Resort
565 Barry Avenue, Summerland Key, FL
10.76 km from city center
Book a stay at this beach motel in Summerland Key. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...

Sugar Loaf Lodge
17001 Overseas Hwy, Summerland Key, FL
8.16 km from city center
Stay at this hotel in Summerland Key. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 7 - Mon, Oct 13
TPA
Tampa Intl.
EYW
Key West Intl.
$77 Roundtrip, found 5 days ago
$77
Roundtrip
found 5 days ago

Mon, Aug 25 - Wed, Sep 3
ORD
O'Hare Intl.
EYW
Key West Intl.
$269 Roundtrip, found 2 days ago
$269
Roundtrip
found 2 days ago

Wed, Nov 12 - Mon, Nov 17
PHL
Philadelphia Intl.
EYW
Key West Intl.
$326 Roundtrip, found 4 days ago
$326
Roundtrip
found 4 days ago

Tue, Jun 10 - Wed, Jun 18
CLT
Charlotte-Douglas Intl.
EYW
Key West Intl.
$574 Roundtrip, found 2 days ago
$574
Roundtrip
found 2 days ago
Best neighborhoods in Lower Keys
Best points of interest in Lower Keys
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All accommodation types in Lower Keys
More Types of Hotels
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