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21c Museum Hotel Louisville

4.5 star property
Luxury hotel with a full-service spa and a 24-hour fitness center

Choose dates to view prices

Photo gallery for 21c Museum Hotel Louisville

Front of property
Interior
Fountain
Bar (on property)
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
Travelers find art and luxury at 21c Museum Hotel Louisville. Enjoy rejuvenating massages at the spa, breakfast and dinner at Proof on Main, a 24-hour gym, and dry cleaning services. Attentive staff handle every need to ensure guests look their best.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Spa
  • Bar
  • Room service
  • 24/7 front desk

Room options

Check availability for these dates

Tonight

Sep 12 - Sep 13
Check availability for tonight Sep 12 - Sep 13

Tomorrow

Sep 13 - Sep 14
Check availability for tomorrow Sep 13 - Sep 14
Available filters for rooms
Showing 12 of 12 rooms

View all photos for Luxury Double Room, 2 Double Beds

Luxury Double Room, 2 Double Beds | Premium bedding, down comforters, minibar, in-room safe

Luxury Double Room, 2 Double Beds

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 40 sq m
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Double Room, 2 Double Beds

Premium bedding, down comforters, minibar, in-room safe

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(29 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 31 sq m
  • Sleeps 4
  • 2 Double Beds

View all photos for Luxury Room, 1 King Bed

Luxury Room, 1 King Bed | Premium bedding, down comforters, minibar, in-room safe

Luxury Room, 1 King Bed

9.0 out of 10
Wonderful
(29 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 42 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed

Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(63 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 33 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, Corner

Suite, Corner | Premium bedding, down comforters, minibar, in-room safe

Suite, Corner

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 61 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Apartment, 1 Double Bed (Rooftop)

Apartment, 1 Double Bed (Rooftop) | Premium bedding, down comforters, minibar, in-room safe

Apartment, 1 Double Bed (Rooftop)

Highlights

Furnished balcony or patio
Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Double Room, Accessible

Premium bedding, down comforters, minibar, in-room safe

Deluxe Double Room, Accessible

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 42 sq m
  • Sleeps 4
  • 2 Double Beds

View all photos for Suite (Atrium)

Suite (Atrium) | Premium bedding, down comforters, minibar, in-room safe

Suite (Atrium)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 54 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Room, Balcony

Room, Balcony | Premium bedding, down comforters, minibar, in-room safe

Room, Balcony

Highlights

Furnished balcony or patio
Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
  • 29 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Room (Asleep in the Cyclone)

Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe

Room (Asleep in the Cyclone)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 46 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 40 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down comforters, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
HDTV
Hypo-allergenic bedding
Blackout drapes/curtains
Down duvet
  • 40 sq m
  • Sleeps 3
  • 1 King Bed

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About the neighborhood

Located in Downtown Louisville, a neighborhood in Louisville, 21c Museum Hotel Louisville is near the airport and near theme parks. Louisville Slugger Museum and KFC Yum Center are cultural highlights, and some of the area's popular attractions include Kentucky Kingdom and Louisville Zoo. Looking to enjoy an event or a game? See what's going on at Churchill Downs or L&N Federal Credit Union Stadium. Practice your golf swing on a nearby course, or enjoy other activities in the great outdoors, such as hiking/biking trails in the area.
Visit our Louisville travel guideOpens in a new window
Map
700 W Main Street, Louisville, KY, 40202

What's nearby

  • Louisville Slugger Museum - 3 min walk - 0.2 miles
  • Fourth Street Live! - 8 min walk - 0.4 miles
  • Kentucky International Convention Center - 8 min walk - 0.5 miles
  • KFC Yum Center - 8 min walk - 0.5 miles
  • Whiskey Row - 8 min walk - 0.5 miles

Getting around

  • Louisville Intl. Airport (SDF) - 10 min drive

Restaurants

  • ‪Evan Williams Bourbon Experience - ‬3 min walk
  • ‪Heine Brothers' Coffee - ‬3 min walk
  • ‪Vincenzo's Italian Restaurant - ‬5 min walk
  • ‪Sunergos Coffee - ‬6 min walk
  • ‪Bristol Bar and Grille - ‬2 min walk

About this property

21c Museum Hotel Louisville

Luxury boutique hotel near KFC Yum Center
Close to Louisville Slugger Museum and Kentucky International Convention Center, 21c Museum Hotel Louisville provides dry cleaning/laundry services, a bar, and a 24-hour gym. Treat yourself to a massage at the onsite spa. The on-site restaurant, Proof on Main, offers breakfast, brunch, lunch, and dinner. In addition to a 24-hour business center, guests can connect to free in-room WiFi.
You'll also enjoy perks such as:
  • Limo/town car service, full breakfast (surcharge), and valet parking (surcharge)
  • An electric car charging station, tour/ticket assistance, and a porter/bellhop
  • An elevator, a gift shop, and massage treatment rooms
  • Guest reviews speak highly of the dining options, helpful staff, and location
Room features
All 91 rooms include comforts such as premium bedding and laptop-compatible safes, in addition to perks like laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the clean rooms at the property.
Extra conveniences in all rooms include:
  • LED light bulbs and eco-friendly cleaning products
  • Bathrooms with designer toiletries and hair dryers
  • 50-inch HDTVs with premium channels
  • Wardrobes/closets, free infant beds, and daily housekeeping

Awards and affiliations

Eco-Certified Property
This property participates in Green Key Global, a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Wheelchair-accessible parking available

Food and drink

  • Daily full breakfast available for a fee: USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Restaurants on site

  • Proof on Main

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Family friendly

  • In-room crib
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Porter/bellhop
  • Tour and ticket assistance
  • Turndown service

Business services

  • 24-hour business center
  • 5,000 square feet of conference space
  • Computer station
  • Meeting rooms

Full-service spa

  • 2 treatment rooms
  • In-room massages

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

More

  • 1 building
  • 4 floors
  • At least 80% lighting from LEDs
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • Built in 2006
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Free crib
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathrobes
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 50-inch LCD TV with premium cable channels
  • iPod dock

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 40.00 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Up to 50 lbs per pet
Food and water bowls are available

Children and extra beds

Children are welcome
Rollaway/extra beds are available for USD 30.0 per night
Free cribs are available on request at the property

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5.00 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
21c Museum
21c Museum Hotel
21c Museum Hotel Louisville
21c Museum Louisville
Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
21c Museum Hotel Louisville MGallery
21c Museum Louisville MGallery
Hotel 21c Museum Hotel Louisville - MGallery Louisville
Louisville 21c Museum Hotel Louisville - MGallery Hotel
21c Museum Hotel Louisville - MGallery Louisville
Hotel 21c Museum Hotel Louisville - MGallery
21c Museum Hotel MGallery
21c Museum MGallery
21c Museum Hotel Louisville
21c Museum Louisville Mgallery
21c Museum Louisville
21c Museum Hotel Louisville Hotel
21c Museum Hotel Louisville MGallery
21c Museum Hotel Louisville Louisville
21c Museum Hotel Louisville Hotel Louisville

Frequently asked questions

Is 21c Museum Hotel Louisville pet-friendly?

Yes, this hotel allows pets with a maximum weight of up to 50 lbs per pet. There's a fee of USD 40.00 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at 21c Museum Hotel Louisville?

Valet parking is available for USD 32 per night.

What time is check-in at 21c Museum Hotel Louisville?

Check-in start time: 4 PM; Check-in end time: midnight.

What time is check-out at 21c Museum Hotel Louisville?

Check-out is at 11 AM.

Where is 21c Museum Hotel Louisville located?

Located in Downtown Louisville, this luxury hotel is steps from 21c Museum Hotel and Louisville Slugger Museum. KFC Yum Center and Fourth Street Live! are also within 10 minutes.

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21c Museum Hotel Louisville Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 761 out of 1000 reviews
Rating 8 - Good. 137 out of 1000 reviews
Rating 6 - Okay. 60 out of 1000 reviews
Rating 4 - Poor. 23 out of 1000 reviews
Rating 2 - Terrible. 19 out of 1000 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Andrea

Liked: Cleanliness, staff & service, property conditions & facilities
Love my stay at this unique musuem hotel!
Stayed 1 night in Aug 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities
I would definitely stay again at this chic hotel chain
Stayed 1 night in Sep 2025

10/10 Excellent

Vaunalee

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We had a great stay and very much enjoyed the art and the atmosphere.
Stayed 2 nights in Aug 2025

10/10 Excellent

Thomas

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent place to stay.
Stayed 1 night in Jun 2025

10/10 Excellent

Cynthia

Liked: Cleanliness, amenities
Favorite in Louisville - such a fun & unique hotel
Stayed 1 night in Aug 2025

10/10 Excellent

JULIA

Liked: Cleanliness, staff & service, property conditions & facilities
What a cool place to stay! It is an art museum. Nice, large room, quiet and very good restaurant. Perfect location for all we wanted to do.
Stayed 1 night in Aug 2025

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very professional staff throughout the entire building- everyone was courteous and helpful during my stay.
Stayed 1 night in Aug 2025

10/10 Excellent

Patricia

Liked: Cleanliness, amenities
The staff was great. Rooms were big and immaculate. Food/drinks were great.
Stayed 3 nights in Aug 2025

10/10 Excellent

Emma

Liked: Cleanliness, staff & service, property conditions & facilities
Loved it
Stayed 1 night in Aug 2025

6/10 Okay

Barrett

Liked: Cleanliness, staff & service
This is a pretty decent hotel that I’ve stayed in many times and enjoyed myself. This time I felt a bit disappointed with the room I was in
Stayed 1 night in Sep 2025

10/10 Excellent

Tom

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great Location. Great hotel. Great team members.
Stayed 2 nights in Jul 2025

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, property conditions & facilities
Nice
Stayed 1 night in Jul 2025

10/10 Excellent

Casey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love this hotel and amenities
Stayed 1 night in May 2025

10/10 Excellent

Sybil

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was great, ver helpful with answering questions about the city. Restaurant had good food and atmosphere. Loved being surrounded by so many wonderful works of art. We would definitely stay again... it's such a vibe.
Stayed 3 nights in Jun 2025

10/10 Excellent

Michael

Was great
Stayed 4 nights in Jun 2025

10/10 Excellent

Daniel M

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Centrally located in downtown. Steps to the Ali Center and Louisville Slugger Museum. Staff was friendly and accommodating.
Stayed 3 nights in Jul 2025

10/10 Excellent

anne delano

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was so incredibly helpful and pleasant.
Stayed 1 night in Jun 2025

10/10 Excellent

Kathryn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The art gallery was fun. Parking was rough but I chose to do valet and that took care of it. It was pricey but worth it to not have to battle finding parking in the area. The hotel was beautiful and so fun and unique. Close to everything!
Stayed 1 night in Jul 2025

10/10 Excellent

Rachel

Liked: Cleanliness, amenities, property conditions & facilities
All around great experience.
Stayed 3 nights in Jun 2025

10/10 Excellent

Wilkins

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property was awesome! Love the art display, the bar in the hotel had friendly staff. Close to everything
Stayed 3 nights in Jun 2025

10/10 Excellent

Ben

Liked: Cleanliness, staff & service, property conditions & facilities
Errthang
Stayed 1 night in Aug 2025

10/10 Excellent

stacy

Liked: Amenities
Great hotel
Stayed 1 night in Mar 2025

10/10 Excellent

Han

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
We were able to check in early. Room is clean and breakfast is great.
Stayed 1 night in May 2025

10/10 Excellent

Paula

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Me and my family stay was super great! We really enjoyed our self. The breakfast was real good, Beds was comfortable.. This place was very laid back and relax.
Stayed 2 nights in May 2025

10/10 Excellent

Beth

Liked: Cleanliness, staff & service, property conditions & facilities
This was an amazing and unique upscale hotel. We enjoyed our stay!
Stayed 1 night in Apr 2025

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