Hilton Jacksonville At Mayo Clinic
Luxury hotel with an outdoor pool and a restaurant
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A short walk from Mayo Clinic Florida, Hilton Jacksonville At Mayo Clinic provides a grocery/convenience store, a firepit, and dry cleaning/laundry services. The on-site American cuisine restaurant, Coastal Kitchen, offers breakfast, lunch, dinner, and kids' meals. Stay connected with free in-room WiFi, with speed of 25+ Mbps, and guests can find other amenities such as a bar and a gym.
Reviews
9.4 out of 10
Exceptional
Popular amenities
Room options
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Showing 20 of 20 rooms
View all photos for Room, 1 King Bed

Room, 1 King Bed
9.0 out of 10
Wonderful
(2 reviews)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Deluxe Room, 1 King Bed (Water View)

Deluxe Room, 1 King Bed (Water View)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Sofa bed - single
Blackout drapes/curtains
Premium bedding
View all photos for Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Junior Suite, 1 King Bed

Junior Suite, 1 King Bed
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Sofa bed - single
Blackout drapes/curtains
Premium bedding
View all photos for Junior Suite, 1 King Bed, Corner

Junior Suite, 1 King Bed, Corner
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Sofa bed - single
Blackout drapes/curtains
Premium bedding
View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 1 King Bed (Zero Count)

Room, 1 King Bed (Zero Count)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 1 King Bed (Water View)

Room, 1 King Bed (Water View)
9.0 out of 10
Wonderful
(2 reviews)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 1 King Bed (Water View, Roll-In Shower)

Room, 1 King Bed (Water View, Roll-In Shower)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 1 King Bed, Accessible (Hearing)

Room, 1 King Bed, Accessible (Hearing)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 1 King Bed, Accessible (Roll-In Shower)

Room, 1 King Bed, Accessible (Roll-In Shower)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 1 King Bed, Accessible (Hearing)

Room, 1 King Bed, Accessible (Hearing)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 2 Queen Beds

Room, 2 Queen Beds
10.0 out of 10
Exceptional
(19 reviews)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 2 Queen Beds, Accessible (Water View, Hearing)

Room, 2 Queen Beds, Accessible (Water View, Hearing)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 2 Queen Beds, Accessible, Bathtub

Room, 2 Queen Beds, Accessible, Bathtub
10.0 out of 10
Exceptional
(1 review)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 2 Queen Beds, Accessible (Hearing)

Room, 2 Queen Beds, Accessible (Hearing)
8.0 out of 10
Very good
(1 review)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 2 Queen Beds (Water View)

Room, 2 Queen Beds (Water View)
10.0 out of 10
Exceptional
(1 review)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
View all photos for Room, 2 Queen Beds, Accessible, Bathtub (View)

Room, 2 Queen Beds, Accessible, Bathtub (View)
Highlights
Air conditioning
Heating
Free cribs/infant beds
Mini-fridge
Smart TV
Blackout drapes/curtains
Premium bedding
Private bathroom
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About the neighborhood

4745 Transformation Way, Jacksonville, FL, 32224
What's nearby
Mayo Clinic Florida1 min walk - 0.0 miles
University of North Florida5 min drive - 5.2 miles
St. Johns Town Center7 min drive - 6.8 miles
TPC Sawgrass12 min drive - 9.1 miles
Mayport Naval Station17 min drive - 11.8 miles
Getting around
- Jacksonville Station28 min drive
- Jacksonville International Airport (JAX)33 min drive
Restaurants
- Culver’s3 min drive
- Starbucks3 min drive
- M Brothers at Mayo14 min walk
- Circle K16 min walk
- Starbucks13 min walk
About this property
Hilton Jacksonville At Mayo Clinic
Similar properties

Sheraton Jacksonville Hotel
Sheraton Jacksonville Hotel
- Pool
- Pet friendly
- Free WiFi
- Restaurant
9.2 out of 10, Wonderful, 1,001 reviews
Property amenities
Room amenities
Policies
Important information
Fees
You'll be asked to pay the following charges at the property. Fees may include applicable taxes:
- Breakage deposit: USD 100 per stay
We have included all charges provided to us by the property.
Optional extras
- Fee for buffet breakfast: approximately USD 26.99 to 26.99 for adults, and USD 15 to 21 for children
- Rollaway bed fee: USD 50.00 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Cashless transactions are available
Safety features at this property include a carbon monoxide detector and a smoke detector
We should mention
Pool access available from 8:00 AM to 10:00 PM
Only registered guests are allowed in the guestrooms
A car is not required for transportation to and from this property
Guests under 16 years old are not allowed in the fitness facility, and guests under 16 years old are only allowed in the swimming pool with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Property is also known as
Hilton Jacksonville At Mayo Clinic Hotel
Hilton Jacksonville At Mayo Clinic Jacksonville
Hilton Jacksonville At Mayo Clinic Hotel Jacksonville
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Reviews
Hilton Jacksonville At Mayo Clinic Reviews
9.4
Exceptional
10
Cleanliness
9.6
Amenities
9.8
Staff & service
10
Property conditions & facilities
Reviews
Jan 9, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Stayed 2 nights in Jan 2026
10/10 Excellent
Julie
Dec 30, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Julie
Stayed 2 nights in Dec 2025
10/10 Excellent
Mohsin
Jan 25, 2026
Liked: Cleanliness, amenities, property conditions & facilities
Mohsin
Stayed 1 night in Jan 2026
10/10 Excellent
Gary
Dec 21, 2025
Gary
Stayed 2 nights in Dec 2025
10/10 Excellent
Christian
Jan 19, 2026
Liked: Cleanliness, property conditions & facilities
Christian
Stayed 1 night in Jan 2026
10/10 Excellent
Erron
Oct 27, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Erron
Stayed 2 nights in Oct 2025
10/10 Excellent
Albert
Oct 17, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Albert
Stayed 1 night in Oct 2025
10/10 Excellent
Joahnna
Nov 2, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Joahnna
Stayed 3 nights in Oct 2025
10/10 Excellent
michael
Dec 17, 2025
Liked: Cleanliness, amenities, property conditions & facilities
michael
Stayed 1 night in Dec 2025
10/10 Excellent
Carrie
Dec 10, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Carrie
Stayed 1 night in Dec 2025
10/10 Excellent
Christy
Dec 24, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Christy
Stayed 1 night in Dec 2025
10/10 Excellent
Steven
Dec 8, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Steven
Stayed 1 night in Dec 2025
10/10 Excellent
Mark
Dec 2, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Mark
Stayed 1 night in Nov 2025
10/10 Excellent
Shearn
Nov 10, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Shearn
Stayed 2 nights in Nov 2025
10/10 Excellent
Jermaine
Nov 30, 2025
Liked: Cleanliness, amenities, property conditions & facilities



Jermaine
Stayed 1 night in Nov 2025
10/10 Excellent
Doria
Dec 16, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Doria
Stayed 1 night in Dec 2025
10/10 Excellent
Shahriar
Nov 15, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Shahriar
Stayed 1 night in Nov 2025
10/10 Excellent
Pratul
Nov 29, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Pratul
Stayed 2 nights in Nov 2025
10/10 Excellent
Varun
Nov 29, 2025
Liked: Cleanliness, amenities
Varun
Stayed 3 nights in Nov 2025
10/10 Excellent
Mousmee
Dec 11, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Mousmee
Stayed 3 nights in Nov 2025
10/10 Excellent
sherry
Dec 20, 2025
Liked: Cleanliness, amenities, property conditions & facilities
sherry
Stayed 3 nights in Dec 2025
10/10 Excellent
Laurie
Oct 27, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Laurie
Stayed 1 night in Oct 2025
6/10 Okay
John
Dec 12, 2025
Liked: Cleanliness, amenities, property conditions & facilities
John
Stayed 1 night in Dec 2025
10/10 Excellent
Kawanna
Dec 14, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Kawanna
Stayed 2 nights in Dec 2025
10/10 Excellent
Aaron
Nov 25, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Aaron
Stayed 1 night in Nov 2025

















