Isola Santa Vacations

Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*

Choose two or more items and save on your trip:

Isola Santa Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
Villa Neroli

Villa Neroli

Coverciano
$1,602
per person
Oct 15 - Oct 21
found 19 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Florence (FLR)
Book a stay at this spa hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Piazza del Duomo and Cathedral of Santa Maria del Fiore are located nearby.
We stayed here for the first part of our honeymoon, and it was perfect! The hotel is beautiful, the rooms are comfortable and specious and the AC was amazing for how hot it was! The property is very well maintained, the pool is lovely and we very much enjoyed the restaurant for breakfast and dinner a few nights. While we loved the quiet location, it is about a 15 minute drive to downtown Florence, so cabs back and forth can get expensive. Regardless, it was an absolutely wonderful stay and would recommend!

Reviewed on Aug 10, 2026

Alfieri9

Alfieri9

Historic Centre of Florence
$1,663
per person
Oct 15 - Oct 21
found 19 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Florence (FLR)
Stay at this hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and valet parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Piazza del Duomo and Cathedral of Santa Maria del Fiore are located nearby.
More quiet residential area of Firenze in walking distance of center but away from the crowds. No elevator and two flight of stairs.

Reviewed on Jul 5, 2026

Corte Guelfa

Corte Guelfa

Historic Centre of Florence
$1,737
per person
Oct 15 - Oct 21
found 19 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Florence (FLR)
Stay at this residence in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions Cathedral of Santa Maria del Fiore and Piazza del Duomo are located nearby.
Air conditioning was unacceptable. It was 96 degrees in Florence (36C) the whole week. The room was 81F (27.4C) when we arrived. The A/C was intentionally neutered to blow air at the lowest setting and the room never cooled down below 79F (26C). Absolutely ridiculous to sweat out your paying customers. Stay somewhere else!

Reviewed on Aug 3, 2026

Il Malaspina

Il Malaspina

Historic Centre of Florence
$1,762
per person
Oct 15 - Oct 21
found 19 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Florence (FLR)
Book a stay at this family-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions Cathedral of Santa Maria del Fiore and Piazza del Duomo are located nearby.
Everything was great!

Reviewed on Aug 9, 2026

Art Hotel Villa Agape

Art Hotel Villa Agape

Oltrarno
$1,741
per person
Oct 15 - Oct 21
found 19 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Florence (FLR)
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a rooftop terrace. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Ponte Vecchio and Cathedral of Santa Maria del Fiore are located nearby.
Great in every way!

Reviewed on Aug 7, 2026

IQ Hotel Firenze

IQ Hotel Firenze

Historic Centre of Florence
$1,812
per person
Oct 15 - Oct 21
found 19 hours ago
Roundtrip non-stop flight included
Raleigh (RDU) to Florence (FLR)
Book a stay at this spa hotel in Florence. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. Popular attractions Piazza del Duomo and Cathedral of Santa Maria del Fiore are located nearby.
Lovely hotel away from the busy centre of Florence. Plunge pool was a definite plus after a hot day of seeing the sites.

Reviewed on Aug 10, 2026

Don't see what you're looking for?
See all available trips from Columbus to Isola Santa
View all trips

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Scandinavian Airlines
KLM
Lufthansa
Air Dolomiti
British Airways