Choose from 3283 Isle of Palms Hotel Deals
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
Free Cancellation
Reserve now, pay when you stay
2.05 km from Isle of Palms
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Margaritaville Jacksonville Beach
715 1st St N, Jacksonville Beach, FL
Free Cancellation
Reserve now, pay when you stay
4.58 km from Isle of Palms
Stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast. Our guests praise the pool and the bar in our reviews. Popular ...
Hampton Inn Jacksonville Beach/Oceanfront
1515 1st St N, Jacksonville Beach, FL
Free Cancellation
Reserve now, pay when you stay
4.96 km from Isle of Palms
Stay at this beach hotel in Jacksonville Beach. Enjoy free breakfast, a beach locale, and 2 bars/lounges. Our guests praise the breakfast and the pool in our ...
Wyndham Garden Jacksonville
4660 Salisbury Road, I-95 Exit 344 (Butler Boulevard), Jacksonville, FL
15.47 km from Isle of Palms
Stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean ...
Southbank Hotel by Marriott Jacksonville Riverwalk
1515 Prudential Dr, Jacksonville, FL
Free Cancellation
Reserve now, pay when you stay
22.05 km from Isle of Palms
Stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast, and room service. Our guests praise the helpful staff and the clean rooms in ...
WaterWalk Jacksonville - Deerwood Park
8895 Perimeter Park Blvd, Jacksonville, FL
Free Cancellation
Reserve now, pay when you stay
12.24 km from Isle of Palms
Stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions St. Johns Town Center ...
Omni Amelia Island Resort
39 Beach Lagoon Road, Fernandina Beach, FL
Free Cancellation
Reserve now, pay when you stay
31.31 km from Isle of Palms
Stay at this 4-star beach resort in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and 9 restaurants. Our guests praise the breakfast and the pool in our ...
DoubleTree by Hilton Hotel Jacksonville Riverfront
1201 Riverplace Boulevard, Jacksonville, FL
Free Cancellation
Reserve now, pay when you stay
22.37 km from Isle of Palms
Stay at this 4-star hotel in Jacksonville. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. ...
Crowne Plaza Hotel Jacksonville Airport/I-95N, an IHG Hotel
14670 Duval Road, Jacksonville, FL
Free Cancellation
31.09 km from Isle of Palms
Stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the restaurant and the helpful staff ...
Hyatt Place Jacksonville Airport
14565 Duval Rd, Jacksonville, FL
Free Cancellation
31.07 km from Isle of Palms
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Hyatt Regency Jacksonville
225 E Coastline Dr, Jacksonville, FL
Free Cancellation
22.31 km from Isle of Palms
Stay at this 4-star business-friendly hotel in Jacksonville. Enjoy free WiFi, 3 restaurants, and breakfast. Our guests praise the restaurant and the helpful ...
Quality Inn Atlantic Beach - Mayo Clinic Jax Area
2401 Mayport Rd, Atlantic Beach, FL
9.01 km from Isle of Palms
Stay at this hotel in Atlantic Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Embassy Suites by Hilton Jacksonville Baymeadows
9300 Baymeadows Road, Jacksonville, FL
Free Cancellation
Reserve now, pay when you stay
14.2 km from Isle of Palms
Stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free parking, and WiFi. Our guests praise the breakfast and the helpful staff in ...
The Villas of Amelia Island
8 Amelia Village Circle, Amelia Island, Fernandina Beach, FL
Free Cancellation
Reserve now, pay when you stay
29.42 km from Isle of Palms
Stay at this 4-star beach resort in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and 9 restaurants. Our guests praise the pool and the helpful staff in ...
One Ocean Resort and Spa
1 Ocean Blvd, Atlantic Beach, FL
Free Cancellation
Reserve now, pay when you stay
6.68 km from Isle of Palms
Stay at this luxury hotel in Atlantic Beach. Enjoy free WiFi, a beach locale, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
Sonesta Simply Suites Jacksonville
4990 Belfort Rd, Jacksonville, FL
Free Cancellation
Reserve now, pay when you stay
15.04 km from Isle of Palms
Stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Isle of Palms, Jacksonville Hotel Guide
Search for hotels in Isle of Palms on Expedia.com. You can easily find your hotels in Isle of Palms using one of the methods below:
- View our selection of featured hotels in Isle of Palms
- Use the map to find hotels in the Isle of Palms neighborhood you prefer
- Use the filters to see hotels in a specific area of Isle of Palms, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Isle of Palms
- Enter your travel dates to view the best deals on hotels in Isle of Palms - while they last
More Isle of Palms Hotel Deals for Seniors and Members
- Residence Inn By Marriott Jacksonville - Mayo Clinic Area
- Margaritaville Jacksonville Beach
- Hampton Inn Jacksonville Beach/Oceanfront
- Wyndham Garden Jacksonville
- Southbank Hotel by Marriott Jacksonville Riverwalk
- WaterWalk Jacksonville - Deerwood Park
- Omni Amelia Island Resort
- DoubleTree by Hilton Hotel Jacksonville Riverfront
- Crowne Plaza Hotel Jacksonville Airport/I-95N, an IHG Hotel
- Hyatt Place Jacksonville Airport