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Hotel Santa Regina

3.0 star property
Travelers find warm hospitality and practical conveniences in this Zona Centro hotel, where staff earn praise for their helpfulness and tour assistance

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Photo gallery for Hotel Santa Regina

Standard Room, 1 King Bed | In-room safe, blackout drapes, iron/ironing board, free WiFi - Hotel Santa Regina (Guanajuato)
View from room - Hotel Santa Regina (Guanajuato)
Lobby - Hotel Santa Regina (Guanajuato)
Front of property - Hotel Santa Regina (Guanajuato)
Family Room | In-room safe, blackout drapes, iron/ironing board, free WiFi - Hotel Santa Regina (Guanajuato)
Hotel Santa Regina in Zona Centro offers a charming city center experience. Guests love the free in-room WiFi and practical amenities like laundry facilities. The 24-hour front desk and concierge team provide tour assistance, consistently praised by previous visitors.

Reviews

8.8 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Laundry
  • Housekeeping
  • 24/7 front desk

Room options

Available filters for rooms
Showing 11 of 11 rooms

View all photos for Double Room

Double Room | In-room safe, blackout drapes, iron/ironing board, free WiFi

Double Room

9.0 out of 10
Wonderful
(7 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Family Room

Family Room | In-room safe, blackout drapes, iron/ironing board, free WiFi

Family Room

10.0 out of 10
Exceptional
(2 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Double Beds and 1 King Bed

View all photos for Standard Room, 1 King Bed

Standard Room, 1 King Bed | In-room safe, blackout drapes, iron/ironing board, free WiFi

Standard Room, 1 King Bed

10.0 out of 10
Exceptional
(7 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Family Room

In-room safe, blackout drapes, iron/ironing board, free WiFi

Family Room

9.0 out of 10
Wonderful
(2 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Double Beds and 1 King Bed

View all photos for Standard Room, 1 King Bed

In-room safe, blackout drapes, iron/ironing board, free WiFi

Standard Room, 1 King Bed

8.0 out of 10
Very good
(1 review)
  • 36 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 King Bed

In-room safe, blackout drapes, iron/ironing board, free WiFi

Standard Room, 1 King Bed

  • 36 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Double Room

In-room safe, blackout drapes, iron/ironing board, free WiFi

Double Room

9.0 out of 10
Wonderful
(2 reviews)
  • City view
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Double Room

In-room safe, blackout drapes, iron/ironing board, free WiFi

Double Room

10.0 out of 10
Exceptional
(1 review)
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Double Room

In-room safe, blackout drapes, iron/ironing board, free WiFi

Double Room

10.0 out of 10
Exceptional
(2 reviews)
  • City view
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Double Room

In-room safe, blackout drapes, iron/ironing board, free WiFi

Double Room

8.0 out of 10
Very good
(1 review)
  • 36 sq m
  • Sleeps 4
  • 2 Double Beds

Standard Room, 1 King Bed

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

About the neighborhood

Located in Guanajuato, Hotel Santa Regina is in the city center. Plaza de San Fernando and Hidalgo Market are local landmarks, and travelers looking to shop may want to visit Plaza Alaïa Guanajuato and Gonzalez Obregon Market. Visit our Guanajuato travel guide
Map
Calle Alonso #26, Guanajuato, GTO, 36000

What's nearby

  • Juarez Theater Guanajuato Mexico
    Juarez Theater
    2 min walk - 0.1 miles
  • Union Garden
    Union Garden
    2 min walk - 0.1 miles
  • Campus and buildings of the University of Guanajuato (Universidad de Guanajuato)
    University of Guanajuato
    2 min walk - 0.1 miles
  • Basilica of Our Lady of Guanajuato
    2 min walk - 0.1 miles
  • Alley of the Kiss
    3 min walk - 0.2 miles

Getting around

  • Bajío Intl. Airport (BJX)
    34 min drive

Restaurants

  • La Tasca de la Paz
    1 min walk
  • Alonso 10 Hotel Boutique & Arte
    1 min walk
  • Mr. Rucio
    1 min walk
  • El Canastillo de Flores
    1 min walk
  • La taberna de Sancho
    1 min walk

About this property

Hotel Santa Regina

Hotel located in Zona Centro
Hotel Santa Regina provides amenities like a free breakfast buffet and laundry facilities. Stay connected with free in-room WiFi.
Additional perks include:
  • Tour/ticket assistance, luggage storage, and smoke-free premises
  • Concierge services, a 24-hour front desk, and a water dispenser
  • An elevator
  • Guest reviews speak highly of the helpful staff
Room features
All guestrooms at Hotel Santa Regina have comforts such as free WiFi and safes.
More amenities include:
  • Bathrooms with showers and free toiletries
  • 32-inch flat-screen TVs with cable channels
  • Ceiling fans and daily housekeeping

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • No onsite parking available

Food and drink

  • Free buffet breakfast available daily 8:00 AM to 11:30 AM

Family friendly

  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Luggage storage
  • Shared refrigerator
  • Water dispenser

Guest services

  • Change of towels on request
  • Concierge services
  • Housekeeping (daily)
  • Tour and ticket assistance

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessibility

More

  • Mosquito nets
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower
  • Towels provided

Entertainment

  • 32-inch flat-screen TV with cable channels

More

  • Ceiling fan
  • Iron/ironing board on request
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: midnight
Contactless check-in available
Late check-in subject to availability
Minimum check-in age: 18

Check-out

Check-out before noon
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

No pets or service animals allowed

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector

We should mention

No pets and no service animals are allowed at this property

Property is also known as

Hotel Santa Regina
Hotel Santa Regina Guanajuato
Santa Regina Guanajuato
Santa Regina
Hotel Santa Regina Hotel
Hotel Santa Regina Guanajuato
Hotel Santa Regina Hotel Guanajuato

Frequently asked questions

Is Hotel Santa Regina pet-friendly?

No, pets are not allowed at this property.

How much is parking?

Hotel Santa Regina doesn't offer parking.

What time is check-in at Hotel Santa Regina?

Check-in start time: 3:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.

What time is check-out at Hotel Santa Regina?

Check-out is at noon.

Where is Hotel Santa Regina located?

Located in Zona Centro, this hotel is steps from La Paz Square, Basilica of Our Lady of Guanajuato, and Museo del Pueblo de Guanajuato. University of Guanajuato and Union Garden are just steps away.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Hotel Santa Regina Reviews

8.8

Excellent

9.4

Cleanliness

9.4

Location

9.2

Staff & service

8.8

Property conditions & facilities
Rating 10 - Excellent. 441 out of 776 reviews
Rating 8 - Good. 243 out of 776 reviews
Rating 6 - Okay. 57 out of 776 reviews
Rating 4 - Poor. 19 out of 776 reviews
Rating 2 - Terrible. 16 out of 776 reviews

Reviews

Verified

10/10 Excellent

Jose A Diaz De

Liked: Cleanliness, amenities, property conditions & facilities
Hotel was very close to historic center and staff was very helpful
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Eric

Liked: Cleanliness, property conditions & facilities
Room was clean, staff was helpful, location is great.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Carlos

Liked: Cleanliness, amenities, property conditions & facilities
I love it especially the front desk guy at night had the best service ever thank you will stay again
Stayed 1 night in Jan 2026
Verified

6/10 Okay

Kim Fah

Central location. Walk around at leisure in the zeno centro area. Many cafes/restaurants around. Breakfast is at another hotel within walking distance. Our room 27 has 1 double bed upstairs and 1 double bed downstairs. The one downstairs can close the bathroom door to outside traffic or noise from outside, but not the upstairs.
Stayed 1 night in Mar 2026
Verified

8/10 Good

Sarna

Liked: Cleanliness, staff & service
Nice hotel, excellent staff, breakfast location was a short walk from the hotel, great area in the historic district. The mattresses could use replacing and if your bothered by late night noise, you’ll want to choose a different property.
Stayed 6 nights in Jan 2026
Verified

8/10 Good

Thierno Sadou

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I will recommend it . At the heart of the downtown. Walking distance at all the mains attractions .Friendly staff
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Sonia

Liked: Cleanliness, staff & service, amenities
Great service
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Centró Guanajuato

Excellent centro location. Breakfast, other property, was great
Stayed 3 nights in Jul 2025
Verified

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, property conditions & facilities
Hotel Santa Regina is located close to many restaurants, bars, attraction, museums, and many places to shop.
Stayed 2 nights in Oct 2024
Verified

10/10 Excellent

Kora

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent! We decided to go come back again for the music festival, beautiful city, amazing and super friendly staff!
Stayed 3 nights in Jun 2025
Verified

10/10 Excellent

Humberto

Liked: Cleanliness, staff & service, property conditions & facilities
The hotel is located in the center of the the town and is very convenient to walk to the main attractions in downtown
Stayed 1 night in Sep 2023
Verified

10/10 Excellent

Diana

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Guanajuato is a place, to just never get tired of visiting it ., hotel was clean simple but i dont have nothing to complain, the breakfast was very delicious 😋 was there for two nights.
Stayed 2 nights in Mar 2025
Verified

10/10 Excellent

Miguel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great property in a very nice area of town. Very walkable, staff at the front desk was friendly and very knowledgeable. We’ll definitely stay there again. Our room in the inside was clean and quiet.
Stayed 3 nights in Sep 2024
Verified

10/10 Excellent

Perla

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice rooms, friendly staff. Close to most of the touristic places. Easy to get around.
Stayed 1 night in Feb 2024
Verified

8/10 Good

Elizabeth

Liked: Cleanliness, staff & service
Great location, a bit noisy but expected to be near bars and roads.
Stayed 4 nights in Oct 2023
Verified

10/10 Excellent

ALEJANDRINA

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to stay very clean, great customer service, they have elevator, great location and breakfast included and it was really good. Great price
Stayed 3 nights in Aug 2023
Verified

10/10 Excellent

Francisco

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It is a fantastic place in an old house And the location is excellent Hotel is clean, staff members are very nice and helpful (to tell the truth, everybody in Guanajuato is) Don’t expect the amenities of the high end American hotels, but, who needs that when you are in the middle of one of the most beautiful cities in the world
Stayed 2 nights in Nov 2023
Verified

8/10 Good

Miguel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
What a pleasant surprise... I was a guest during MEX Independence celebrations in Sept 2023. There are nicer hotels in the area; however, they are much more expensive. The location is close to everything and the room I got had double layered windows that cut noise levels dramatically. I stayed in room # 41. It faces Calle Alonso. Furthermore, the site has an elevator and that helped with my bad knee. The breakfast was off site and ok. I only went once. I didn't give the site five stars because: THE ROOMS HAVE NO AC - SO, BE WARNED ABOUT STAYING HERE DURING HOT MONTHS. I just opened my room window and used the ceiling fan. I had no problem getting good night rest because I always travel with ear plugs and the street noise didn't bother me.
Verified

8/10 Good

MI

Liked: Cleanliness
Good location and great breakfast.
Stayed 3 nights in Dec 2025
Verified

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Simple but clean with a complementary bottle of wine
Stayed 4 nights in Feb 2026
Verified

10/10 Excellent

Pankaj Kumar Omprakash

Liked: Property conditions & facilities
Nice hotel to stay
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Julius

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I really enjoyed my stay at this hotel. Jesus, at the front desk was amazing. I loved the rooms and the proximity to everything. I have already booked this hotel again in May 2026. If i had one suggestion, it would be to have the breakfast vouchers valid at more than one place.
Stayed 4 nights in Dec 2025
Verified

8/10 Good

Grace

Liked: Cleanliness, staff & service, amenities
Jesús and Rosie were wonderful and very knowledgeable. Clean room.
Stayed 7 nights in Jan 2026
Verified

10/10 Excellent

Gamaliel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

miguel

Liked: Cleanliness, staff & service, property conditions & facilities
Great place to stay
Stayed 2 nights in Mar 2023