Santo Spirito

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Things to do

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

$22
per adult
80% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

$33
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Best of Florence Tour with Fast Track Accademia & Duomo

Best of Florence Tour with David at Accademia & Duomo (with VIP option)

$76
per adult
96% of travellers recommend
Best of Florence Tour with David at Accademia & Duomo (with VIP option)
Florence half day combo tour with David, Uffizi & Duomo

Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option

$41
per adult
92% of travellers recommend
Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

$74
per adult
92% of travellers recommend
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
Uffizi Gallery Small Group Tour with Guide

Uffizi Gallery Small Group Tour with Guide

$77
per adult
96% of travellers recommend
Uffizi Gallery Small Group Tour with Guide
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Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
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Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Cathedral of Santa ...
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La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
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UNA Hotels Vittoria Firenze
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
Stay at this guesthouse in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...
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Foresteria Valdese di Firenze - Casa per Ferie
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
Stay at this residence in Florence. Enjoy free WiFi, concierge services, and premium bedding. Our guests praise the helpful staff in our reviews. Popular attractions ...
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Palazzo Mannaioni Suites
Hostel Santa Monaca

Hostel Santa Monaca

Via Santa Monaca 6 Florence FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza della ...
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Hostel Santa Monaca
See all 523 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
A river with buildings on the right bank.

Historic Centre of Florence

Cathedral of Santa Maria del Fiore and Piazza della Signoria are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral, and stunning river views.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Cathedral of Santa Maria del Fiore and Piazza del Duomo are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Signoria are top sights worth seeing.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

An ornate building with intricate architectural details and a clear blue sky in the background.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito

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