Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Choose from 721 Downtown Hotel Deals

See all 721 Properties in Downtown

Estimated price for 1 night/2 adults

Clayton Plaza Hotel

Clayton Plaza Hotel

7750 Carondelet Avenue, St. Louis, MO
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 

Located in Downtown, this hotel is 0.2 mi (0.3 km) from Plaza Clayton and within 3 mi (5 km) of Washington University and Forest Park. St. Louis Zoo and St. ...

Clayton Plaza HotelGet Rates

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza, St. Louis, MO
  • Free Cancellation
  • Reserve now, pay when you stay
4.5 out of 5.0
 
 

Located in Downtown, this luxury hotel is 0.1 mi (0.2 km) from Plaza Clayton and within 3 mi (5 km) of Washington University and Forest Park. St. Louis Zoo and ...

The Ritz-Carlton, St. LouisGet Rates

Seven Gables Inn

Seven Gables Inn

26 North Meramec Avenue, St. Louis, MO
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 

Located in Downtown, this romantic hotel is 0.5 mi (0.8 km) from Plaza Clayton and within 3 mi (5 km) of Washington University and Forest Park. St. Louis Art ...

Seven Gables InnGet Rates

Sheraton Clayton Plaza Hotel St. Louis

Sheraton Clayton Plaza Hotel St. Louis

7730 Bonhomme Ave, St. Louis, MO
    3.5 out of 5.0
     
     

    Located in Downtown, this hotel is 0.3 mi (0.4 km) from Plaza Clayton and within 3 mi (5 km) of Washington University and Forest Park. St. Louis Zoo and St. ...

    Sheraton Clayton Plaza Hotel St. LouisGet Rates

    Hyatt Regency St. Louis at The Arch

    Hyatt Regency St. Louis at The Arch

    315 Chestnut St, St. Louis, MO
    • Free Cancellation
    4.0 out of 5.0
     
     

    Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse and Gateway Arch. Dome at America’s Center and Busch Stadium are also ...

    Hyatt Regency St. Louis at The ArchGet Rates

    Drury Plaza Hotel St. Louis at the Arch

    Drury Plaza Hotel St. Louis at the Arch

    2 South 4th Street, St. Louis, MO
    • Free Cancellation
    • Reserve now, pay when you stay
    3.0 out of 5.0
     
     

    Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse, Gateway Arch, and Busch Stadium. Dome at America’s Center and America's ...

    Drury Plaza Hotel St. Louis at the ArchGet Rates

    The Parkway Hotel

    The Parkway Hotel

    4550 Forest Park Ave, St. Louis, MO
    • Free Cancellation
    • Reserve now, pay when you stay
    3.0 out of 5.0
     
     

    Located in Central West End, this hotel is within a 10-minute walk of Forest Park, Barnes Jewish Hospital, and World Chess Hall of Fame. Cathedral Basilica of ...

    The Parkway HotelGet Rates

    Hollywood Casino & Hotel St. Louis

    Hollywood Casino & Hotel St. Louis

    777 Casino Center Drive, Maryland Heights, MO
    • Free Cancellation
    • Reserve now, pay when you stay
    3.5 out of 5.0
     
     

    Situated near the airport, this hotel is 1.4 mi (2.2 km) from Hollywood Casino Amphitheatre and within 9 mi (15 km) of Historic Main Street and Lindenwood University. ...

    Hollywood Casino & Hotel St. LouisGet Rates

    The Last Hotel

    The Last Hotel

    1501 Washington Ave, St. Louis, MO
    • Free Cancellation
    • Reserve now, pay when you stay
    4.0 out of 5.0
     
     

    Located in Downtown St. Louis, this hotel is steps from Washington Avenue Historic District and City Museum. America's Center Convention Complex and Enterprise ...

    The Last HotelGet Rates

    Drury Inn St. Louis at Union Station

    Drury Inn St. Louis at Union Station

    201 S 20th St, St. Louis, MO
    • Free Cancellation
    • Reserve now, pay when you stay
    3.0 out of 5.0
     
     

    Located in Downtown St. Louis, this hotel is within a 10-minute walk of Washington Avenue Historic District and Enterprise Center. City Museum and Busch Stadium ...

    Drury Inn St. Louis at Union StationGet Rates

    Pear Tree Inn St. Louis Near Union Station

    Pear Tree Inn St. Louis Near Union Station

    2211 Market Street, St. Louis, MO
      3.0 out of 5.0
       
       

      Located in Downtown St. Louis, this hotel is within 1 mi (2 km) of Washington Avenue Historic District, Enterprise Center, and City Museum. America's Center ...

      Pear Tree Inn St. Louis Near Union StationGet Rates

      Hawthorn Suites by Wyndham St. Louis Westport Plaza

      Hawthorn Suites by Wyndham St. Louis Westport Plaza

      1881 Craigshire Rd, Maryland Heights, MO
      • Free Cancellation
      • Reserve now, pay when you stay
      3.0 out of 5.0
       
       

      Situated near the airport, this hotel is 5.6 mi (9.1 km) from St. Louis Car Museum and within 12 mi (20 km) of Sophia M. Sachs Butterfly House and St. Louis ...

      Hawthorn Suites by Wyndham St. Louis Westport PlazaGet Rates

      Marriott St. Louis Grand

      Marriott St. Louis Grand

      800 Washington Ave, St. Louis, MO
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       

      Located in Downtown St. Louis, this romantic hotel is steps from Washington Avenue Historic District and America's Center Convention Complex. Dome at America’s ...

      Marriott St. Louis GrandGet Rates

      The Westin St. Louis

      The Westin St. Louis

      811 Spruce St, St. Louis, MO
      • Free Cancellation
      • Reserve now, pay when you stay
      4.5 out of 5.0
       
       

      Located in Downtown St. Louis, this luxury hotel is within a 15-minute walk of Busch Stadium and Enterprise Center. Dome at America’s Center and Gateway Arch ...

      The Westin St. LouisGet Rates

      Ameristar Casino Resort and Spa (St. Charles)

      Ameristar Casino Resort and Spa (St. Charles)

      1 Ameristar Blvd, St. Charles, MO
      • Free Cancellation
      • Reserve now, pay when you stay
      4.5 out of 5.0
       
       

      Located in the heart of St. Charles, this luxury hotel is within 3 mi (5 km) of Lindenwood University, Family Arena, and Katy Trail. Jaycee Park and Hollywood ...

      Ameristar Casino Resort and Spa (St. Charles)Get Rates

      Hilton St. Louis Downtown at the Arch

      Hilton St. Louis Downtown at the Arch

      400 Olive St, St. Louis, MO
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       

      Located in Downtown St. Louis, this romantic hotel is within a 10-minute walk of Security Building, Dome at America’s Center, and America's Center Convention ...

      Hilton St. Louis Downtown at the ArchGet Rates

      Stay in Downtown's best neighborhoods

      Downtown, St. Louis Hotel Guide

      Search for hotels in Downtown on Expedia.com. You can easily find your hotels in Downtown using one of the methods below:

      • View our selection of featured hotels in Downtown
      • Use the map to find hotels in the Downtown neighborhood you prefer
      • Use the filters to see hotels in a specific area of Downtown, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Downtown
      • Enter your travel dates to view the best deals on hotels in Downtown - while they last