Cheap 2025 Downtown Clayton Hotels
Photo by Najib Tecle
Choose from 1771 Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
0.02 km from Downtown Clayton
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
AC Hotel St. Louis Clayton
227 South Central Ave, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
0.33 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
The Ritz-Carlton, St. Louis
100 Carondelet Plaza, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
0.5 km from Downtown Clayton
Stay at this 5-star luxury hotel in St. Louis. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the room ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
13.19 km from Downtown Clayton
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
13.13 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
The Arch Convention Hotel
811 N 9th Street, St. Louis, MO
Free Cancellation
12.65 km from Downtown Clayton
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive, Fenton, MO
16.4 km from Downtown Clayton
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Pear Tree Inn St. Louis Near Union Station
2211 Market Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
11.01 km from Downtown Clayton
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Moonrise Hotel
6177 Delmar Blvd, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
3.37 km from Downtown Clayton
Stay at this 4-star boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the bar in our reviews. ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
12.76 km from Downtown Clayton
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the bar and the helpful ...
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
17.02 km from Downtown Clayton
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
21C Museum Hotel St Louis
1528 Locust street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
11.83 km from Downtown Clayton
Stay at this 4.5-star luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Best Western St. Louis-Kirkwood Route 66
1200 S Kirkwood Road, Kirkwood, MO
Free Cancellation
Reserve now, pay when you stay
11.37 km from Downtown Clayton
Stay at this 3.5-star business-friendly hotel in Kirkwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street, St. Louis, MO
Free Cancellation
Reserve now, pay when you stay
11.43 km from Downtown Clayton
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms ...
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd, Maryland Heights, MO
10.54 km from Downtown Clayton
Stay at this hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Downtown Clayton, St. Louis Hotel Guide
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More Downtown Clayton Hotel Deals for Seniors and Members
- Clayton Plaza Hotel & Extended Stay
- AC Hotel St. Louis Clayton
- The Ritz-Carlton, St. Louis
- Hyatt Regency St. Louis at The Arch
- Drury Plaza Hotel St. Louis at the Arch
- The Arch Convention Hotel
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Pear Tree Inn St. Louis Near Union Station
- Moonrise Hotel
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel