Cheap 2026 Downtown Clayton Hotels
Photo by Najib Tecle
Choose from 1775 Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.02 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.33 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.5 km from Downtown Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.2 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13.19 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
12.76 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Hilton St. Louis Airport
10330 Natural Bridge Rd St. Louis MO
Free Cancellation
Reserve now, pay when you stay
9.95 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13.13 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
11.83 km from Downtown Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13.23 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
16.4 km from Downtown Clayton
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
12.2 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, valet parking (surcharge), and a 24-hour front desk. Our guests praise the helpful ...
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Free Cancellation
Reserve now, pay when you stay
10.44 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Free Cancellation
Reserve now, pay when you stay
9.18 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
17.02 km from Downtown Clayton
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
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