Cheap 2026 Downtown Clayton Hotels
Choose from 1853 Downtown Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.02 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.5 km from Downtown Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.22 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.33 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13.14 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
11.01 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
11.82 km from Downtown Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free Cancellation
Reserve now, pay when you stay
17.02 km from Downtown Clayton
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Free Cancellation
Reserve now, pay when you stay
13.19 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
River City Casino & Hotel
777 River City Casino Blvd St. Louis MO
Free Cancellation
Reserve now, pay when you stay
14.69 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
16.4 km from Downtown Clayton
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites St. Louis Union Station
201 S 20th St St. Louis MO
11.28 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Free Cancellation
Reserve now, pay when you stay
10.44 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hilton St. Louis Airport
10330 Natural Bridge Rd St. Louis MO
Free Cancellation
Reserve now, pay when you stay
9.95 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy 2 restaurants, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
Best Western St. Louis-Kirkwood Route 66
1200 S Kirkwood Road Kirkwood MO
Free Cancellation
Reserve now, pay when you stay
11.31 km from Downtown Clayton
Book a stay at this business-friendly hotel in Kirkwood. Enjoy free parking, an outdoor pool, and room service. Our guests praise the breakfast and the helpful ...
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Free Cancellation
Reserve now, pay when you stay
9.28 km from Downtown Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
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