Downtown Isle of Palms Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
The Palms Oceanfront Hotel
1126 Ocean Blvd Isle of Palms SC
Book a stay at this beach hotel in Isle of Palms. Enjoy a beach locale, parking (surcharge), and a 24-hour front desk. Our guests praise the breakfast and the ...
Seaside Inn Oceanfront
1004 Ocean Blvd Isle of Palms SC
Book a stay at this beach hotel in Isle of Palms. Enjoy free WiFi, a beach locale, and parking (surcharge). Our guests praise the helpful staff and the clean ...
Emeline
181 Church St Charleston SC
Book a stay at this luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the restaurant and the helpful ...
The Francis Marion Hotel
387 King St Charleston SC
Book a stay at this luxury hotel in Charleston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the restaurant and the helpful ...
Harborside at Charleston Harbor Resort and Marina
20 Patriots Point Rd Mount Pleasant SC
Book a stay at this beach resort in Mount Pleasant. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our ...
Hotel Indigo Mount Pleasant by IHG
250 Johnnie Dodds Boulevard Mount Pleasant SC
Book a stay at this business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
The Ryder Hotel
237 Meeting Street Charleston SC
Stay at this hotel in Charleston. Enjoy 2 bars/lounges, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the helpful staff in ...
Tides Folly Beach, Charleston's Oceanfront Hotel
1 Center Street Highway 171 Folly Beach SC
Book a stay at this beach hotel in Folly Beach. Enjoy 2 restaurants, a beach locale, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff ...
The Beach Club at Charleston Harbor Resort and Marina
28 Patriots Point Road Mount Pleasant SC
Book a stay at this luxury resort in Mount Pleasant. Enjoy free parking, 2 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful ...
The Charleston Place
205 Meeting Street Charleston SC
Book a stay at this luxury hotel in Charleston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property ...
Andrew Pinckney Inn
40 Pinckney St Charleston SC
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and valet parking (surcharge). Our guests praise the breakfast and ...
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
5757 Palm Boulevard Isle of Palms SC
Book a stay at this beach resort in Isle of Palms. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
The Palmetto Hotel
194 East Bay Street Charleston SC
Stay at this hotel in Charleston. Enjoy free breakfast, free WiFi, and free bicycles on site. Our guests praise the breakfast and the helpful staff in our reviews. ...
Cambria Hotel Mount Pleasant – Charleston
1472 Highway 17 North Mount Pleasant SC
Book a stay at this business-friendly hotel in Mount Pleasant. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
Drury Plaza Hotel North Charleston
West Montague Avenue, 2934 North Charleston SC
Book a stay at this business-friendly hotel in North Charleston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Charleston Tanger Outlets ...
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See all available properties in Downtown Isle of Palms
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Tue, Oct 13 - Sat, Oct 17
JFK
John F. Kennedy Intl.
CHS
Charleston Intl.
$199
Roundtrip
found 3 days ago
Sun, Oct 11 - Sat, Oct 17
LGA
LaGuardia
CHS
Charleston Intl.
$248
Roundtrip
found 3 days ago
Sat, Nov 14 - Sun, Nov 15
JFK
John F. Kennedy Intl.
CHS
Charleston Intl.
$298
Roundtrip
found 7 hours ago
Mon, Sep 21 - Fri, Sep 25
SWF
Stewart Intl.
CHS
Charleston Intl.
$313
Roundtrip
found 6 days ago
Wed, Oct 14 - Wed, Oct 21
ORD
O'Hare Intl.
CHS
Charleston Intl.
$313
Roundtrip
found 2 days ago
Best points of interest in Isle of Palms
- Isle of Palms County Park Vacations
- Windjammer Vacations
- College of Charleston Vacations
- Charleston City Market Vacations
- Patriots Point Vacations
- Wild Dunes Resort Golf Course Vacations
- Medical University of South Carolina Vacations
- Waterfront Park Vacations
- North Charleston Coliseum Vacations
- South Carolina Aquarium Vacations
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