Adults Only Resorts & Hotels in Missouri
Check availability on Missouri Adults Only Resorts & Hotels
Pick from 24 Missouri Adults Only Resorts & Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Westport Inn
Westport Inn
8.2 out of 10, Very Good, (688)
"Everything was perfect, safe and quiet compared your traditional hotels. I will stay there again when I visit family."
James
Historic Iron Horse Inn
Historic Iron Horse Inn
8.4 out of 10, Very Good, (21)
"The inn keeper was fabulous. The rooms were clean and cozy. Will defiantly be back. "
Trina
Moonrise Hotel
Moonrise Hotel
9.0 out of 10, Wonderful, (1906)
"Always love staying at the moonrise."
Jarrod
Chateau On The Lake Resort Spa and Convention Center
Chateau On The Lake Resort Spa and Convention Center
8.6 out of 10, Excellent, (1385)
"Beautiful Property. Nice rooms, lovely restaurant , comfortable lounge all within a beautiful setting. "
Patricia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Missouri Hotel Reviews
Explore a world of travel with Expedia
Top destinations for Adults Only Resorts & Hotels in Missouri
More Hotel Options in Missouri
- Hotels with Air Conditioning in Missouri
- Hotels with WiFi in Missouri
- Family Hotels in Missouri
- Hotel with wifi in Missouri
- Hotels with a Pool in Missouri
- Hotels with Complimentary Breakfast in Missouri
- Smoke Free Hotels in Missouri
- Pet-friendly Hotels in Missouri
- Cheap Hotels in Missouri
- Hotels with Hot Tubs in Missouri
- Hotels with an Indoor Pool in Missouri
- Hotels with Bars in Missouri
- Luxury Hotels in Missouri
- Resorts & Hotels with Spas in Missouri
- Hotels with Balconies in Missouri
More Themes
- Hotels with Air Conditioning
- All-inclusive Hotel
- Hotels with Balconies
- Hotels with Bars
- Beach Hotels
- Boutique Hotels
- Cheap Hotels
- Business Hotels
- Casinos
- Hotel with a Concierge
- Hotels with Restaurants
- Family Hotels
- Hotels with Fireplaces
- Hotels with a Fitness Center
- Hotels with Free Airport Shuttle
- Hotels with Complimentary Breakfast
- Hotels with Free Parking
- Hotel with wifi
- Golf Hotels
- Historic Hotels
- Hotels with Hot Tubs
- Hotels with an Indoor Pool
- Apartment Hotel
- Hotels with a Kitchen
- Lakefront Hotels
- Hotels with a Lazy River
- Gay friendly Hotels
- Luxury Hotels
- Smoke Free Hotels
- Oceanfront Hotels
- Pet-friendly Hotels
- Hotels with a Pool
- Adventure Hotels
- Hotels on the River
- Romantic Hotels
- Hotels with Room Service
- Secluded Hotels
- Shopping Hotels
- Ski Hotels
- Hotels with smoking rooms
- Resorts & Hotels with Spas
- Hotels with Suites
- Green Hotels
- Hotels with Tennis Courts
- Waterpark Hotels
- Hotels with Waterslides
- Hotel Wedding Venues
- Hotels with WiFi
- Winery Hotels
Stay near popular Missouri attractions
- Hotels near GEHA Field at Arrowhead Stadium
- Hotels near Busch Stadium
- Hotels near St. Louis Union Station
- Hotels near Table Rock Lake
- Hotels near Gateway Arch
- Hotels near Worlds of Fun
- Hotels near Branson Landing
- Hotels near Silver Dollar City
- Hotels near Kauffman Stadium
- Hotels near Washington University in St. Louis
Discover hotels close to Missouri with room rates, reviews, and availability. Most hotels are fully refundable.
- Thousand Hills Resort Hotel
- The Stone Castle Hotel & Conference Center
- Loews Kansas City Hotel
- Clayton Plaza Hotel & Extended Stay
- Pear Tree Inn St. Louis Airport
- Renaissance St. Louis Airport Hotel
- Drury Plaza Hotel St. Louis at the Arch
- American Inn North Kansas City
- Hyatt Vacation Club at The Lodges at Timber Ridge, Branson
- Lodge Of The Ozarks