Defiance, MO

Travel Guide

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

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Defiance Hotel Deals

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive Maryland Heights MO

Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...

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Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

1088 South Highway Drive Fenton MO

Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

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The Wildwood Hotel

2801 Fountain Pl Wildwood MO

Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

Gateway Arch

Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's fascinating museums or attend a baseball game.

St. Louis Zoo

Why not visit the animals who live at St. Louis Zoo and see why this is a popular attraction in St. Louis? Amble around the area's lush forest or attend a sporting event.