Defiance, MO

Travel Guide

A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.
A calm lake with a solitary tree on a small island, surrounded by a forested shoreline.
A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.
A restaurant with outdoor seating and a blue sign.
A glass of red wine on a wooden table with a vineyard in the background.
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
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Hollywood Casino & Hotel St. Louis
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3 out of 5
15431 Conway Rd Chesterfield MO
Stay at this hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
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Sonesta ES Suites St. Louis - Chesterfield
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
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Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
See all 898 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Defiance attractions

A glass of red wine on a wooden table with a vineyard in the background.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

7.8/10 (7 reviews)
You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savor the top-notch restaurants.
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Things to do

The Boom Boom Room St. Louis Burlesque and Cabaret Show

St. Louis Burlesque & Nightlife Experience at The Boom Boom Room

$60
per adult
St. Louis Burlesque & Nightlife Experience at The Boom Boom Room
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

$25
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

$24
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
Landmarks Downtown-West Walking Tour

Landmarks Downtown-West Walking Tour

$20
per adult
Landmarks Downtown-West Walking Tour
Saint Louis Self Guided Driving and Walking Audio Tour

St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour

$17
per traveler
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
Picture 1 for Activity St. Louis: Museum of Illusions Entry Ticket

St. Louis: Museum of Illusions Entry Ticket

$35
per adult
90% of travellers recommend
St. Louis: Museum of Illusions Entry Ticket
See all activities in Defiance

Cities near Defiance

A forested cliff with autumn foliage and a clear sky.

Wentzville

A town with a prominent church spire, residential buildings, and a hill in the background.

Chesterfield

A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

St. Charles

A city skyline with a prominent arch bridge and a lit bridge over a calm river reflecting city lights.

O'Fallon