
De Soto Vacations
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals

Edgetowner Motel
804 Guthrie St, De Soto, IA
0.51 km from city center
Book a stay at this business-friendly motel in De Soto. Enjoy free parking, a business center, and a garden. Popular attractions Van Meter Recreation Complex ...

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd, Urbandale, IA
28.98 km from city center
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Quality Inn & Suites Des Moines - Merle Hay Road
4995 Merle Hay Rd, Des Moines, IA
29.01 km from city center
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave, Des Moines, IA
30.21 km from city center
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Motel 6 West Des Moines, IA
7655 Office Plaza Dr N, West Des Moines, IA
17.53 km from city center
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...

Sonesta Essential Des Moines
4755 Merle Hay Road, Des Moines, IA
28.81 km from city center
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

Stoney Creek Hotel Des Moines - Johnston
5291 Stoney Creek Court, Johnston, IA
26.69 km from city center
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...

GrandStay Hotel & Suites
6215 Merle Hay Road, Johnston, IA
30.23 km from city center
Enjoy free breakfast, free WiFi, and free parking. Popular attractions Iowa Gold Star Military Museum and Merle Hay Mall are located nearby.

Drury Inn & Suites West Des Moines
5505 Mills Civic Pkwy, West Des Moines, IA
19.03 km from city center
Stay at this 3-star business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Country Inn & Suites by Radisson, Des Moines West, IA
1350 Nw 118th St, Clive, IA
20.65 km from city center
Stay at this 3-star business-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...

Wildwood Lodge
11431 Forest Ave, Clive, IA
21.01 km from city center
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...

Hyatt Place West Des Moines Jordan Creek
295 South 64th st, West Des Moines, IA
17.97 km from city center
Stay at this 3-star business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr, West Des Moines, IA
17.95 km from city center
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Nov 6 - Mon, Nov 17
DEN
Denver Intl.
DSM
Des Moines Intl.
$72 Roundtrip, found 5 hours ago
$72
Roundtrip
found 5 hours ago

Tue, Nov 4 - Fri, Nov 14
DEN
Denver Intl.
DSM
Des Moines Intl.
$143 Roundtrip, found 5 hours ago
$143
Roundtrip
found 5 hours ago

Tue, Nov 4 - Fri, Nov 14
DEN
Denver Intl.
DSM
Des Moines Intl.
$153 Roundtrip, found 5 hours ago
$153
Roundtrip
found 5 hours ago

Tue, Nov 4 - Sat, Nov 15
DEN
Denver Intl.
DSM
Des Moines Intl.
$177 Roundtrip, found 2 days ago
$177
Roundtrip
found 2 days ago

Fri, May 15 - Mon, May 25
SEA
Seattle - Tacoma Intl.
DSM
Des Moines Intl.
$637 Roundtrip, found 5 days ago
$637
Roundtrip
found 5 days ago