Clayton Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Clayton Flight + Hotel packages
Price found within the past 48 hours. Click for updated prices.
White House at Grand Central
Grand Center
Price was $638, price is now $428 per person
$428
per person
Apr 6 - Apr 11
found 4 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
Stay at this apartment in St. Louis. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
The Wildwood Hotel
Save 100% on your flight
Price was $855, price is now $450 per person
$450
per person
Apr 6 - Apr 11
found 4 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Six Flags St. Louis and Skid Row are located nearby.
Hilton Garden Inn Chesterfield
Price was $733, price is now $525 per person
$525
per person
Apr 6 - Apr 11
found 4 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
Book a stay at this business-friendly hotel in Chesterfield. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions The J - Chesterfield Gym & Fitness Center and Topgolf are located nearby.
Ameristar Casino Resort and Spa
Save 100% on your flight
Price was $799, price is now $579 per person
$579
per person
Feb 19 - Feb 23
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTT) to St. Louis (STL)
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Lewis & Clark Boathouse and Nature Center are located nearby.
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Price was $735, price is now $548 per person
$548
per person
Feb 19 - Feb 23
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTT) to St. Louis (STL)
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Hampton Inn By Hilton St Louis Airport
Woodson Terrace
Price was $698, price is now $521 per person
$521
per person
Apr 6 - Apr 11
found 4 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
Stay at this hotel in St. Louis. Enjoy free breakfast, free WiFi, and a free airport shuttle. Popular attractions Payne-Gentry Historical House and Blanche M. Touhill Performing Arts Center are located nearby.
Top Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
1.34 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
The Ritz-Carlton, St. Louis
100 Carondelet Plaza St. Louis MO
0.95 km from Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
1.21 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
216 N Meramec Ave St. Louis MO
1.89 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
1.41 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
11.95 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
333 Washington Ave St. Louis MO
12 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
11.53 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
10.6 km from Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
11.89 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
10.97 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, valet parking (surcharge), and a 24-hour front desk. Our guests praise the helpful ...
Live by Loews - St.Louis
799 Clark ave St. Louis MO
11.46 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful ...
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
3550 Samuel Sheppard Drive St. Louis MO
8.11 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Mar 4 - Sat, Mar 7
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$68 Roundtrip, found 6 days ago
$68
Roundtrip
found 6 days ago
Tue, Mar 3 - Wed, Mar 4
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$189 Roundtrip, found 6 days ago
$189
Roundtrip
found 6 days ago
Wed, Apr 1 - Sat, Apr 4
LGA
LaGuardia
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Wed, Apr 1 - Sat, Apr 4
LGA
LaGuardia
STL
Lambert-St. Louis Intl.
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Tue, Apr 14 - Sat, Apr 18
EWR
Newark Liberty Intl. Airport
STL
Lambert-St. Louis Intl.
$309 Roundtrip, found 1 day ago
$309
Roundtrip
found 1 day ago