Clayton Vacation Packages for 2025

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Top Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
1.34 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
1.41 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
0.95 km from Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
1.21 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave St. Louis MO
1.89 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
11.53 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Forest Park Hotel by MDR

Forest Park Hotel by MDR

3 out of 5
5915 Wilson Ave St. Louis MO
4.25 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
9.77 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
11.88 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
11.95 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
16.72 km from Clayton
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
10.6 km from Clayton
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66

3.5 out of 5
1200 S Kirkwood Road Kirkwood MO
11.46 km from Clayton
Book a stay at this business-friendly hotel in Kirkwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
12 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
10.06 km from Clayton
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Sun, Dec 14 - Fri, Jan 2
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$104 Roundtrip, found 5 days ago
$104
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, Dec 14 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Fri, Jan 2, priced at $104 found 5 days ago
Frontier Airlines
Sun, Dec 14 - Thu, Jan 1
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$104 Roundtrip, found 5 days ago
$104
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, Dec 14 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Thu, Jan 1, priced at $104 found 5 days ago
Delta
Tue, Jan 6 - Sun, Jan 18
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$197 Roundtrip, found 5 days ago
$197
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Jan 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jan 18, priced at $197 found 5 days ago
Alaska Airlines
Tue, Apr 21 - Tue, Apr 28
LAX
Los Angeles Intl.
STL
Lambert-St. Louis Intl.
$314 Roundtrip, found 5 days ago
$314
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Tue, Apr 21 from Los Angeles Intl. to Lambert-St. Louis Intl., returning Tue, Apr 28, priced at $314 found 5 days ago