Central Iowa Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Gateway Hotel and Conference Center at Iowa State University
2100 Green Hills Drive Ames IA
Book a stay at this business-friendly hotel in Ames. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
Sonesta Essential Des Moines
4755 Merle Hay Road Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
GrandStay Hotel & Suites
6215 Merle Hay Road Johnston IA
Stay at this hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Iowa Gold Star Military Museum and Merle Hay Mall are ...
Stoney Creek Hotel Des Moines - Johnston
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Country Inn & Suites by Radisson, Des Moines West, IA
1350 Nw 118th St Clive IA
Book a stay at this business-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
Embassy Suites Hotel Des Moines Downtown
101 E Locust St Des Moines IA
Stay at this hotel in Des Moines. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in ...
Des Lux Hotel
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
La Quinta Inn & Suites by Wyndham Des Moines West Clive
1390 Nw 118th St Clive IA
Book a stay at this family-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Wildwood Lodge
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Drury Inn & Suites West Des Moines
5505 Mills Civic Pkwy West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Sep 16 - Fri, Sep 25
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$232
Roundtrip
found 4 days ago
Thu, Sep 10 - Tue, Sep 22
ATL
Hartsfield-Jackson Atlanta Intl.
RST
Rochester Intl.
$323
Roundtrip
found 6 days ago
Sat, Sep 26 - Wed, Oct 7
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$354
Roundtrip
found 6 days ago
Sat, Oct 24 - Wed, Oct 28
SEA
Seattle - Tacoma Intl.
DSM
Des Moines Intl.
$355
Roundtrip
found 4 days ago
Sat, Sep 26 - Wed, Oct 7
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$356
Roundtrip
found 6 days ago
Best points of interest in Central Iowa
- Adventureland Vacations
- Jordan Creek Town Center Vacations
- Iowa State University Vacations
- Iowa State Fairgrounds Vacations
- Drake University Vacations
- Casey's Center Vacations
- Knoxville Raceway Vacations
- Jack Trice Stadium Vacations
- Iowa Events Center Vacations
- Prairie Meadows Racetrack and Casino Vacations
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All accommodation types in Central Iowa
More Types of Hotels
- Hotels with WiFi in Central Iowa
- Hotels with Air Conditioning in Central Iowa
- Hotel with wifi in Central Iowa
- Family Hotels in Central Iowa
- Hotels with Complimentary Breakfast in Central Iowa
- Hotels with a Pool in Central Iowa
- Hotels with an Indoor Pool in Central Iowa
- Pet-friendly Hotels in Central Iowa
- Smoke Free Hotels in Central Iowa
- Hotels with Hot Tubs in Central Iowa
- Hotels with Bars in Central Iowa
- Cheap Hotels in Central Iowa
- Resorts & Hotels with Spas in Central Iowa
- Luxury Hotels in Central Iowa
- Casinos in Central Iowa
- Hotels with smoking rooms in Central Iowa
- Hotels with Free Airport Shuttle in Central Iowa
- Lakefront Hotels in Central Iowa
- Hotels with Balconies in Central Iowa
- Hotels with Fireplaces in Central Iowa
- Hotel with a Concierge in Central Iowa
- Beach Hotels in Central Iowa
- Hotels with Waterslides in Central Iowa
- Hotels with Tennis Courts in Central Iowa
- Hotels with Early Check-in in Central Iowa
- Hotels on the River in Central Iowa
- Adults Only Resorts & Hotels in Central Iowa
- All-inclusive Hotel in Central Iowa