Central Iowa Vacation Packages for 2026
Build a Flight + Hotel Bundle & Save up to $536 On Your Vacation*
Top Hotel Deals
Gateway Hotel and Conference Center at Iowa State University
2100 Green Hills Drive Ames IA
Book a stay at this business-friendly hotel in Ames. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff and the clean rooms ...
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
Sonesta Essential Des Moines
4755 Merle Hay Road Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Stoney Creek Hotel Des Moines - Johnston
5291 Stoney Creek Court Johnston IA
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the breakfast and ...
Motel 6 Des Moines, IA - North
4940 NE 14th Street Des Moines IA
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Casey's Center and Iowa State Fairgrounds are ...
Country Inn & Suites by Radisson, Des Moines West, IA
1350 Nw 118th St Clive IA
Book a stay at this business-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
La Quinta Inn & Suites by Wyndham Des Moines West Clive
1390 Nw 118th St Clive IA
Book a stay at this family-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Embassy Suites Hotel Des Moines Downtown
101 E Locust St Des Moines IA
Stay at this hotel in Des Moines. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in ...
Fairfield Inn and Suites by Marriott Des Moines West
7225 Vista Dr West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites West Des Moines
5505 Mills Civic Pkwy West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Des Lux Hotel
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Flight Deals
These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.
Wed, Sep 16 - Fri, Sep 25
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$232
Roundtrip
found 4 days ago
Tue, Sep 15 - Tue, Sep 22
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$349
Roundtrip
found 5 days ago
Tue, Sep 15 - Tue, Sep 22
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$354
Roundtrip
found 5 days ago
Tue, Sep 15 - Tue, Sep 22
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$354
Roundtrip
found 5 days ago
Sat, Sep 19 - Mon, Sep 21
DEN
Denver Intl.
DSM
Des Moines Intl.
$366
Roundtrip
found 1 day ago
Best points of interest in Central Iowa
- Adventureland Vacations
- Iowa State University Vacations
- Jordan Creek Town Center Vacations
- Iowa State Fairgrounds Vacations
- Drake University Vacations
- Casey's Center Vacations
- Iowa Events Center Vacations
- Jack Trice Stadium Vacations
- Prairie Meadows Racetrack and Casino Vacations
- Knoxville Raceway Vacations
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All accommodation types in Central Iowa
More Types of Hotels
- Hotels with WiFi in Central Iowa
- Hotels with Air Conditioning in Central Iowa
- Hotel with wifi in Central Iowa
- Family Hotels in Central Iowa
- Hotels with Complimentary Breakfast in Central Iowa
- Hotels with a Pool in Central Iowa
- Hotels with an Indoor Pool in Central Iowa
- Pet-friendly Hotels in Central Iowa
- Smoke Free Hotels in Central Iowa
- Hotels with Hot Tubs in Central Iowa
- Hotels with Bars in Central Iowa
- Cheap Hotels in Central Iowa
- Resorts & Hotels with Spas in Central Iowa
- Luxury Hotels in Central Iowa
- Casinos in Central Iowa
- Hotels with smoking rooms in Central Iowa
- Hotels with Free Airport Shuttle in Central Iowa
- Lakefront Hotels in Central Iowa
- Hotels with Balconies in Central Iowa
- Hotels with Fireplaces in Central Iowa
- Hotel with a Concierge in Central Iowa
- Beach Hotels in Central Iowa
- Hotels with Waterslides in Central Iowa
- Hotels with Tennis Courts in Central Iowa
- Hotels with Early Check-in in Central Iowa
- Hotels on the River in Central Iowa
- Adults Only Resorts & Hotels in Central Iowa
- All-inclusive Hotel in Central Iowa