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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property
Travelers start their day with a complimentary breakfast buffet before exploring downtown Buffalo or catching a show at nearby Shea's Performing Arts Center

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Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Free daily buffet breakfast - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Lobby sitting area - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Business center - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Lobby sitting area - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Located in downtown Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR offers a free breakfast buffet in a welcoming atmosphere. Guests enjoy in-room WiFi, gym access, and dry cleaning/laundry services. The attentive staff consistently earns positive reviews.

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Room options

Available filters for rooms
Showing 4 of 4 rooms

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.0 out of 10
Wonderful
(28 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(52 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

About the neighborhood

Located in Downtown Buffalo, a neighborhood in Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is in the entertainment district and near a metro station. CEPA Gallery and Road Less Traveled Productions are cultural highlights, and some of the area's popular attractions include Market Arcade Building and Shea's Performing Arts Center. Andrews Theatre and Fountain Plaza are two other places to visit that come recommended. Spend some time exploring the area's activities, including golfing. Visit our Buffalo travel guide
Map
601 Main St, Buffalo, NY, 14203

What's nearby

  • Chippewa District
    Chippewa District
    1 min walk - 0.0 miles
  • McKinley Monument on Niagara Square in Buffalo - NY, USA
    Niagara Square
    8 min walk - 0.5 miles
  • Shea's Performing Arts Center
    2 min walk - 0.1 miles
  • Fountain Plaza
    2 min walk - 0.1 miles
  • Buffalo Niagara Convention Center
    6 min walk - 0.4 miles

Getting around

  • Fountain Plaza Station
    1 min walk
  • Buffalo-Exchange Street Station
    18 min walk
  • Buffalo Niagara Intl. Airport (BUF)
    21 min drive

Restaurants

  • Tap House Pub & Grill
    4 min walk
  • Big Ditch Brewing Company
    4 min walk
  • Bada Bing
    2 min walk
  • Eddie Brady's
    3 min walk
  • Lucky Day Whiskey Bar
    4 min walk

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Children up to the age of 18 years can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Nearby parking fee: USD 16.00 per day (500 ft away)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property

We should mention

Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG pet-friendly?

No, only service animals are welcome at the property.

What time is check-in at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

What time is check-out at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG located?

Located in Downtown Buffalo, this hotel is steps from Market Arcade Building, Buffalo Music Hall of Fame, and CEPA Gallery. Buffalo Visitor Center and Fountain Plaza are just steps away. Fountain Plaza Station is only a 2-minute walk and Lafayette Square Station is 5 minutes.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

8.6

Excellent

8.8

Cleanliness

8.2

Amenities

8.8

Staff & service

8.6

Property conditions & facilities
Rating 10 - Excellent. 572 out of 1026 reviews
Rating 8 - Good. 275 out of 1026 reviews
Rating 6 - Okay. 81 out of 1026 reviews
Rating 4 - Poor. 44 out of 1026 reviews
Rating 2 - Terrible. 54 out of 1026 reviews

Reviews

Verified

10/10 Excellent

Danyal

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great breakfast, clean room and great location
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Kate

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Heather was amazing at the breakfast station all morning!!!! Rooms were very clean and great to stay in!
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Linda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice room, good breakfast with many choices, no on site parking
Stayed 1 night in May 2026
Verified

8/10 Good

Janine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was great and staff was friendly and helpful.
Stayed 2 nights in Mar 2026
Verified

8/10 Good

Daniel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice room, clean, convenient location to why we were in town. However the recommended parking was off-site and about 2 blocks away. Having to walk that multiple times was a bit annoying.
Stayed 1 night in Jun 2026
Verified

8/10 Good

Brooke

Liked: Cleanliness, property conditions & facilities
Overall it was a good booking, a little trash under bed, a little Trouble at first with our booking but, once we were set staff was amazing, along with security!!
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Rossana

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
On a business trip. Hotel was clean, comfortable and close to restaurants. there is an upscale Indian restaurant attached to the hotel. I did not try it, but it will be on my list for my next visit. The hotel is near hospitals and the Roswell Cancer Center which was an easy, safe and pleasant 20 minute walk. Definitely will stay here again. Thank you to all the staff for making my visit comfortable and pleasant.
Stayed 2 nights in May 2026
Verified

8/10 Good

tressa

Liked: Cleanliness, amenities, property conditions & facilities
You have to park two blocks away in a ramp and pay.. my car got broken into while I stayed two nights broke my car door lock that was the biggest downside the property itself is fine. The breakfast is good for a hotel.
Stayed 2 nights in May 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Julie

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room clean most comfortable bed I have ever slept in!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Sharon

Liked: Cleanliness, amenities, property conditions & facilities
Rooms were very clean. Staff was very accommodating. Just very enjoyable stay.
Stayed 4 nights in Feb 2026
Verified

6/10 Okay

Andrew

Liked: Staff & service
Disliked: Cleanliness, property conditions & facilities
The hotel is a bit worn, staff was very pleasant. Pressure vessel in the toilet was not working, sink tap kept running and the AC sounded like a gurgle jug of water. The air in the hallways was very stale in the morning - no fresh air movement. Overall give it a pass.
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Dharani

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff are helpful
Stayed 1 night in Feb 2026
Verified

6/10 Okay

Jeff

Liked: Staff & service
No on-site parking available - had to park at a public parking lot at an additional cost. Room was ok, but we didn’t have enough towels and the phones in the room didn’t work properly, unable to contact housekeeping or guest services. The sofa bed was uneven, with the feet portion being higher than the head section and the mattress was too soft. Huge plus was the continental breakfast available in the morning.
Stayed 1 night in Jun 2026
Verified

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was just as pictured a one bedroom suite, clean, quiet hotel, parking garage was 2 short blocks down from the property reasonable pricing well lit, for being in the city felt very safe, not a lot of dining options close by, breakfast had a large variety. I would definitely stay again.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Eden

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and friendly
Stayed 1 night in Feb 2026
Verified

8/10 Good

Scott

Liked: Cleanliness, amenities
Super friendly and curtious. Breakfast was awesome!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

RYAN

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Rooms were large. Breakfast was good and very friendly and helpful staff
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very clean. Larger than I expected. Quiet at night. Highly recommend!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Daniel

Liked: Cleanliness, staff & service, property conditions & facilities
Clean, nice staff, good breakfast
Stayed 3 nights in Oct 2025
Verified

8/10 Good

Daniel

Liked: Cleanliness, staff & service, amenities
Rooms were clean and the breakfast was very good. Traveled with our kids and 4 grandkids. They had a great time
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
In town for a concert, staff very helpful with recommendations for travel and dining
Stayed 1 night in Dec 2025