Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property
Travelers start their day with a complimentary breakfast buffet before exploring downtown Buffalo or catching a show at nearby Shea's Performing Arts Center

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Lobby sitting area - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
1 bedroom, in-room safe, desk, laptop workspace - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Business center - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Lobby sitting area - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Free daily buffet breakfast - Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG (Buffalo)
Located in downtown Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR offers a free breakfast buffet in a welcoming atmosphere. Guests enjoy in-room WiFi, gym access, and dry cleaning/laundry services. The attentive staff consistently earns positive reviews.

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Room options

Available filters for rooms
Showing 4 of 4 rooms

Standard Room

9.2 out of 10
Wonderful
(25 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

Suite, 1 Bedroom

8.8 out of 10
Excellent
(48 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed

About the neighborhood

Located in Downtown Buffalo, a neighborhood in Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is in the entertainment district and near a metro station. CEPA Gallery and Road Less Traveled Productions are cultural highlights, and some of the area's popular attractions include Market Arcade Building and Shea's Performing Arts Center. Andrews Theatre and Fountain Plaza are two other places to visit that come recommended. Spend some time exploring the area's activities, including golfing. Visit our Buffalo travel guide
Map
601 Main St, Buffalo, NY, 14203

What's nearby

  • Beautiful restaurant in downtown Buffalo. This is fois gras on a dark berry tart. Melts in your mouth.
    Chippewa District
    1 min walk - 0.0 miles
  • Niagara square in downtown buffalo.
    Niagara Square
    6 min walk - 0.4 miles
  • Shea's Performing Arts Center
    2 min walk - 0.1 miles
  • Road Less Traveled Theater
    2 min walk - 0.1 miles
  • Buffalo Niagara Convention Center
    5 min walk - 0.3 miles

Getting around

  • Fountain Plaza Station
    1 min walk
  • Buffalo-Exchange Street Station
    18 min walk
  • Buffalo Niagara Intl. Airport (BUF)
    21 min drive

Restaurants

  • Bada Bing
    2 min walk
  • Big Ditch Brewing Company
    4 min walk
  • Tap House Pub & Grill
    4 min walk
  • Lucky Day Whiskey Bar
    4 min walk
  • Starbucks
    4 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Hotel near Shea's Performing Arts Center
Located close to Buffalo Music Hall of Fame and Market Arcade Building, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG provides a free breakfast buffet, dry cleaning/laundry services, and a gym. In addition to a business center, guests can connect to free in-room WiFi.
You'll also find perks like:
  • Express check-out, a vending machine, and smoke-free premises
  • A 24-hour front desk, luggage storage, and a front-desk safe
  • An elevator
  • Guest reviews say great things about the helpful staff
Room features
All 146 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to perks like free WiFi and separate sitting areas. Guest reviews speak positively of the clean rooms at the property.
More amenities include:
  • Sofa beds and free cribs/infant beds
  • Bathrooms with eco-friendly toiletries and shower/tub combinations
  • 49-inch TVs with cable channels
  • Wardrobes/closets, separate sitting areas, and LED light bulbs

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets not allowed (service animals are welcome, and are exempt from fees)

Children and extra beds

Children are welcome
Children up to the age of 18 years can stay for free if using existing beds when occupying the parent or guardian's room
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Optional extras

  • Nearby parking fee: USD 16.00 per day (500 ft away)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property

We should mention

Only registered guests are allowed in the guestrooms
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

Is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG pet-friendly?

No, only service animals are welcome at the property.

What time is check-in at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

What time is check-out at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-out is at 11 AM.

Where is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG located?

Located in Downtown Buffalo, this hotel is steps from Market Arcade Building, Buffalo Music Hall of Fame, and CEPA Gallery. Buffalo Visitor Center and Fountain Plaza are just steps away. Fountain Plaza Station is only a 2-minute walk and Lafayette Square Station is 5 minutes.

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Reviews

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

8.6

Excellent

8.8

Cleanliness

8.8

Location

8.8

Staff & service

8.6

Property conditions & facilities
Rating 10 - Excellent. 560 out of 1000 reviews
Rating 8 - Good. 276 out of 1000 reviews
Rating 6 - Okay. 70 out of 1000 reviews
Rating 4 - Poor. 41 out of 1000 reviews
Rating 2 - Terrible. 53 out of 1000 reviews

Reviews

Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was just as pictured a one bedroom suite, clean, quiet hotel, parking garage was 2 short blocks down from the property reasonable pricing well lit, for being in the city felt very safe, not a lot of dining options close by, breakfast had a large variety. I would definitely stay again.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026
Verified

8/10 Good

Scott

Liked: Cleanliness, amenities
Super friendly and curtious. Breakfast was awesome!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Eden

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and friendly
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Brittany

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was very clean. Larger than I expected. Quiet at night. Highly recommend!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Paul

Liked: Cleanliness, amenities, property conditions & facilities
The room was clean, the staff were AMAZING, especially Mario and Eddie on the front desk!!! I cannot say how incredible the overall experience was. Would highly recommend
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
In town for a concert, staff very helpful with recommendations for travel and dining
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Daniel

Liked: Cleanliness, staff & service, property conditions & facilities
Clean, nice staff, good breakfast
Stayed 3 nights in Oct 2025
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, amenities, property conditions & facilities
When I say that this hotel has the best breakfast that I’ve ever had at a hotel, I am not exaggerating. So many things to choose from but OMG… The hot cinnamon rolls. Amazing. The room was adequate. The living room TV didn’t work, but it didn’t affect me or my stay but let them know on checkout of the problem. Nothing too fancy, but it was perfect for attending a concert around the corner at Electric City. You need to park offsite but that two is a very easy walk and parking is super cheap. I would definitely stay here again.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Emma

Liked: Cleanliness, staff & service, property conditions & facilities
Staff was warming and friendly!
Stayed 1 night in Oct 2025
Verified

8/10 Good

Neil

Liked: Cleanliness, amenities, property conditions & facilities
Staff very helpful. No parking on site, less than 5 min. walk to parking garage with a fee, $12 per day.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

annmarie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were there for the the worlds largest disco. It made it a super convenient walk to the convention center. Great room too!! Friendly staff, we would love to stay again. Thank you!!
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Todd

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great Stay!

Very nice room, good breakfast and friendly staff. Would stay again.
Stayed 2 nights in Jun 2025
Verified

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, property conditions & facilities
Night staff was super friendly and welcoming! Rooms are spacious and comfortable
Stayed 1 night in Oct 2025
Verified

6/10 Okay

Brad

Staff bey nice, especially BW! Had a
Stayed 2 nights in Oct 2025
Verified

4/10 Poor

Diana

Nice rooms Did not have breakfast
Stayed 2 nights in Sep 2025
Verified

10/10 Excellent

Tracy

Liked: Cleanliness, staff & service, property conditions & facilities
Good location, nice rooms
Stayed 1 night in Apr 2025
Verified

8/10 Good

Wilson

Nice location, the room was clean and comfortable.
Stayed 3 nights in Apr 2025
Verified

10/10 Excellent

Daryl

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very simple yet comfortable rooms
Stayed 2 nights in Sep 2025
Verified

10/10 Excellent

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities
Great staff - great room - thank you
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Merry

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff made our stay an excellent experience. They were fantastic. The room was very large and comfortable. All in all, a very good experience.
Stayed 2 nights in Oct 2025
Verified

8/10 Good

laura

Liked: Cleanliness, staff & service, room comfort

Good Location and hearty breakfast included

Very good location, staff was friendly and helpful and a pretty substantial breakfast offering which remained decently stocked even nearing the end of service time. Room was large and comfortable. Hotel itself seems a bit aged , but suited all of our needs for a family gathering and was appropriate for the price we paid.
Stayed 3 nights in Oct 2025
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, property conditions & facilities
Great service
Stayed 1 night in Sep 2025