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Hotel Museo Spa Casa Santo Domingo

4.5 star property
This boutique hotel in Antigua's historic district blends history with luxury, offering spa treatments and exceptional restaurants for a memorable Guatemala getaway

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Photo gallery for Hotel Museo Spa Casa Santo Domingo

Interior entrance - Hotel Museo Spa Casa Santo Domingo (Antigua Guatemala)
Creator video - submitted by Sallytrubella Travel Shop
Couples treatment rooms, sauna, hot tub, body treatments, aromatherapy - Hotel Museo Spa Casa Santo Domingo (Antigua Guatemala)
Building design - Hotel Museo Spa Casa Santo Domingo (Antigua Guatemala)
Standard Room, 1 King Bed, Jetted Tub (All rooms are different) | Jetted tub - Hotel Museo Spa Casa Santo Domingo (Antigua Guatemala)
Hotel Museo Spa Casa Santo Domingo, in Antigua's historical district, offers a poolside bar, spa treatments, and the Casa Santo Domingo Museum. Enjoy fusion cuisine at two restaurants. Central Park is a short walk away, and ziplining adds excitement to this cultural retreat.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Air conditioning

Room options

Available filters for rooms
Showing 12 of 12 rooms

View all photos for Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

  • Garden view
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Spa Living (All rooms are different)

Standard Spa Living (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Standard Spa Living (All rooms are different)

9.2 out of 10
Wonderful
(11 reviews)
  • Sleeps 2
  • 2 Double Beds

View all photos for Superior Suite Spa Living (All rooms are different)

Superior Suite Spa Living (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Superior Suite Spa Living (All rooms are different)

10.0 out of 10
Exceptional
(3 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room (All rooms are different)

Standard Room (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Standard Room (All rooms are different)

9.0 out of 10
Wonderful
(33 reviews)
  • Garden view
  • 19 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Standard Room, 1 King Bed, Jetted Tub (All rooms are different)

Standard Room, 1 King Bed, Jetted Tub (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Standard Room, 1 King Bed, Jetted Tub (All rooms are different)

10.0 out of 10
Exceptional
(5 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Executive Suite (All rooms are different)

Executive Suite (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Executive Suite (All rooms are different)

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Exclusive Suite, 1 King Bed (All rooms are different)

Exclusive Suite, 1 King Bed (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Exclusive Suite, 1 King Bed (All rooms are different)

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Executive Suite, 1 King Bed (All rooms are different)

Executive Suite, 1 King Bed (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Executive Suite, 1 King Bed (All rooms are different)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite (All rooms are different) (2 adults, 2 children)

Junior Suite (All rooms are different) (2 adults, 2 children) | Premium bedding, minibar, in-room safe, iron/ironing board

Junior Suite (All rooms are different) (2 adults, 2 children)

9.6 out of 10
Exceptional
(4 reviews)
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Suite (All rooms are different)

Deluxe Suite (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Deluxe Suite (All rooms are different)

10.0 out of 10
Exceptional
(5 reviews)
  • Garden view
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed

View all photos for Suite (All rooms are different)

Suite (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Suite (All rooms are different)

10.0 out of 10
Exceptional
(3 reviews)
  • Garden view
  • 1 bedroom
  • Sleeps 2
  • 1 Double Bed

View all photos for Superior Suite, Jetted Tub (All rooms are different)

Superior Suite, Jetted Tub (All rooms are different) | Premium bedding, minibar, in-room safe, iron/ironing board

Superior Suite, Jetted Tub (All rooms are different)

9.4 out of 10
Exceptional
(3 reviews)
  • Sleeps 4
  • 2 Double Beds

About the neighborhood

Located in Antigua Guatemala, Hotel Museo Spa Casa Santo Domingo is in the historical district. Las Capuchinas Convent and Palacio del Ayuntamiento are local landmarks, and travelers looking to shop may want to visit Jade Maya Factory and Museum and Nim Po't Traditional Textiles Center. House of the Giants and La Azotea Cultural Center are also worth visiting. Visit our Antigua Guatemala travel guide
Map
3a Calle Oriente No 28 A, Antigua Guatemala, Sacatepequez, 3001

What's nearby

  • Palacio de los Capitans Antigua, Guatemala
    Central Park
    6 min walk - 0.4 miles
  • The Santa Catalina arch and the main street of Antigua city at sunrise, Guatemala.
    Santa Catalina Arch
    8 min walk - 0.5 miles
  • Antigua Guatemala Cathedral
    Antigua Guatemala Cathedral
    8 min walk - 0.5 miles
  • Casa Santo Domingo Museum
    1 min walk - 0.0 miles
  • Las Capuchinas Convent
    5 min walk - 0.3 miles

Getting around

  • La Aurora Intl. Airport (GUA)
    68 min drive

Restaurants

  • Clio’s Antigua
    3 min walk
  • Café No Sé
    6 min walk
  • El Comalote
    2 min walk
  • Bar El Cabildo
    1 min walk
  • El Muro
    3 min walk

About this property

Hotel Museo Spa Casa Santo Domingo

Luxury boutique hotel near Casa Santo Domingo Museum
Close to Antigua Guatemala Cathedral and Central Park, Hotel Museo Spa Casa Santo Domingo provides a poolside bar, a terrace, and a garden. Indulge in a facial, a body treatment, and a body scrub at the onsite spa. At the two on-site restaurants, enjoy breakfast, lunch, dinner, and Fusion cuisine. Enjoy the health club, as well as activities like ziplining. In addition to a hair salon and dry cleaning/laundry services, guests can connect to free WiFi in public areas.
Other perks at this hotel include:
  • An outdoor pool
  • Free self parking
  • Full breakfast (surcharge), a roundtrip airport shuttle (surcharge), and an electric car charging station
  • Express check-out, smoke-free premises, and luggage storage
  • Guest reviews speak highly of the helpful staff and first-rate property condition
Room features
All 132 rooms include comforts such as fireplaces and premium bedding, as well as perks like pillow menus and air conditioning.
Extra conveniences in all rooms include:
  • Rollaway/extra beds (surcharge) and cribs/infant beds (surcharge)
  • Bathrooms with tubs or showers and hair dryers
  • 42-inch Smart TVs with premium channels
  • Daily housekeeping and phones

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Property amenities

Internet

  • Available in some public areas: Free WiFi

Parking and transportation

  • Electric car charging station on site
  • 24-hour roundtrip airport shuttle (surcharge)
  • Free self parking on site
  • Wheelchair-accessible parking available
  • Onsite parking includes off-street options

Food and drink

  • Daily full breakfast available 7:00 AM to 11:00 AM for a fee: USD 20 per person
  • 2 bars/lounges
  • 2 restaurants
  • A poolside bar

Restaurants on site

  • El Refrectorio
  • El Tenedor Del Cerro

Things to do

  • Full-service spa
  • Health club
  • Outdoor pool
  • Sauna
  • Steam room
  • Ziplining

Family friendly

  • Crib (surcharge)
  • Laundry facilities
  • Outdoor pool
  • Rollaway/extra bed (surcharge)

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Guidebooks
  • Hair salon
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Water dispenser

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Tour and ticket assistance

Business services

  • Business center
  • Conference space
  • Meeting rooms

Outdoors

  • Garden
  • Terrace
  • Vegetable garden

Full-service spa

  • Aromatherapy
  • Body scrubs
  • Body wraps
  • Couples treatment rooms
  • Facials
  • Hot tub
  • Manicures/pedicures
  • Massage
  • Sauna
  • Spa open daily

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • No elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant

More

  • 1 building
  • 2 floors
  • At least 80% lighting from LEDs
  • Banquet hall
  • Built in 1989
  • Comprehensive recycling policy
  • Local artist showcase
  • Smoking not allowed

Room amenities

Bedroom

  • Crib (surcharge)
  • Pillow menu
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathtub or shower
  • Hair dryer
  • Private bathroom
  • Towels provided

Entertainment

  • 42-inch smart TV with premium cable channels

Food and drink

  • Limited room service
  • Minibar
  • Restaurant dining guides

More

  • Air conditioning
  • Connecting rooms available
  • Fireplace
  • Iron/ironing board
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: midnight
Early check-in subject to availability
Late check-in subject to availability
Minimum check-in age: 18

Check-out

Check-out before noon
Late check-out subject to availability
A late check-out fee will be charged
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
For any questions, please contact the property using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 61 per pet, per night
Welcoming dogs only
1 total (up to 25 lbs per pet)
Pets cannot be left unattended
Restrictions apply; for more information contact the property at the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are available for USD 48.8 per day
Cribs (infant beds) are available for USD 9.76 per day

Property payment types

Important information

Optional extras

  • Fee for full breakfast: approximately USD 20 per person
  • Airport shuttle fee: USD 60 per person (one-way)
  • Pet fee: USD 61 per pet, per night
  • Late check-out is available for a fee (subject to availability)
  • Crib (infant bed) fee: USD 9.76 per day
  • Rollaway bed fee: USD 48.8 per day

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards and cash
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
This property uses a grey water recycling system
Safety features at this property include a fire extinguisher, a smoke detector, and a first aid kit
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
This property charges a fee of USD 45 per night for use of the sofabed.

We should mention

This property does not have elevators
Reservations are required for massage services and spa treatments; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Guests under 18 years old are not allowed in the spa

Frequently asked questions

Does Hotel Museo Spa Casa Santo Domingo have a pool?

Yes, this property has an outdoor pool.

Is Hotel Museo Spa Casa Santo Domingo pet-friendly?

Yes, Hotel Museo Spa Casa Santo Domingo allows dogs (limit 1 total) with a maximum weight of up to 25 lbs per pet. There's a fee of USD 61 per pet, per night. Some restrictions may apply, so please contact the property for more details.

How much is parking?

Self parking is free at this property.

What time is check-in at Hotel Museo Spa Casa Santo Domingo?

Check-in start time: 3:00 PM; Check-in end time: midnight. Late check-in is available during limited hours.

What time is check-out at Hotel Museo Spa Casa Santo Domingo?

Check-out is at noon. Late check-out is available for a fee (subject to availability).

Does Hotel Museo Spa Casa Santo Domingo provide a shuttle to the airport?

Yes, there's an airport shuttle. A fee of USD 60 per person applies.

Where is Hotel Museo Spa Casa Santo Domingo located?

Located in Barrio de La Concepción, this luxury hotel is within a 10-minute walk of Casa Santo Domingo Museum, Central Park, and Antigua Guatemala Cathedral. Iglesia y Convento de Santo Domingo and Jade Maya Factory and Museum are just steps away.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Hotel Museo Spa Casa Santo Domingo Reviews

9.2

Wonderful

9.8

Cleanliness

9.4

Amenities

9.4

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 826 out of 1057 reviews
Rating 8 - Good. 118 out of 1057 reviews
Rating 6 - Okay. 53 out of 1057 reviews
Rating 4 - Poor. 30 out of 1057 reviews
Rating 2 - Terrible. 30 out of 1057 reviews

Reviews

Verified

10/10 Excellent

juan pablo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great Staff. Great food. Amazing place
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

eve

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The most enchanting hotel I’ve ever had the privilege to stay in. We adored the antique-adorned decor, the beautiful breakfast, interacting with the warm staff, enjoying the pools, discovering the museums.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Clarissa

The hotel is just imersed with history. The staff was outstanding
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Lindsay

Liked: Cleanliness, amenities, property conditions & facilities
Food amazing specially the breakfast!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Linda

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful property, great service, would definitely recommend for a luxurious stay in Antigua
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

oliver

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was just great. Room was cleaned , AC working great. Had a bit of a problem lighting up the fireplace.
Stayed 4 nights in Apr 2026
Verified

10/10 Excellent

Yesica Rivera

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was amazing. So comfy, and cozy. I would definitely come back . It is in my top 2 hotels to stay at. Food is amazing. It started to down poor and it was so convenient that we could eat at the hotel. Room service is also amazing and fast.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Roberto

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is definitely one of the best hotels in Antigua, Guatemala. It's such a lovely setting, the ambiance, the amenities, the room, all wonderful. Friendly and courteous staff make you feel at home. A bonus is that you can park your car before you check in, and everything is within walking distance, which saves the hassle of finding parking around Antigua, which can be quite challenging. I definitely recommend staying here!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Stefany

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
All staff was very friendly and location was convenient
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Taslima

Liked: Cleanliness, amenities, property conditions & facilities
This was probably one of the most beautiful hotels I've ever stayed in! The grounds and rooms are just absolutely stunning and well-maintained. The service and staff was impeccable. We would absolutely stay here again!
Balcony drink!
On-site ruins
Room service available!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Carolina

Liked: Cleanliness, property conditions & facilities
Clean room, incredible staff , spa , gardens , food. Amazing Hotel
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Cesar Luis Sinclair

Liked: Cleanliness, amenities, property conditions & facilities
Great room, the food was awesome and the amenities are just amazing.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Hector A

Liked: Cleanliness, amenities, property conditions & facilities
Great Breakfast Buffet. The hotel is in the entrance of Antigua, so it´s about 4,000 steps from the Cathedral and the park (where restaurants and coffe shops are). Nice rooms (clean, TV, bathtub, etc). The Hotel has abot 3 museums inside. This hotel was build on a ancient catholic convent where monks and priests lived their religious life. There are catacombs with the remains of the people that lived there. Trully, the only real 5 star hotel in Central America.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Rebecca

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We loved the history and the museums and artifacts throughout this hotel. A beautiful property with excellent service.
Stayed 3 nights in Dec 2025
Verified

10/10 Excellent

Raymond

Liked: Cleanliness, amenities, property conditions & facilities
Wonderful staff, a very well maintained property and beautiful room.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Nina

Liked: Cleanliness, amenities, property conditions & facilities
Amazing property beautiful views and grounds large spacious room w a jacuzzi! Lovely staff and restaurant i wish i had more time in antigua and could check out the spa! Ill be back and stay here again
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Lorena

Liked: Cleanliness, amenities, property conditions & facilities
staff super courteous, room is amazing
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Marie Andree

Liked: Cleanliness, property conditions & facilities
Everything was great, the staff very nice and the food was very tasty. We love to stay at Santo Domingo
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Gregory

Liked: Cleanliness, staff & service, amenities
This hotel is amazing … and is, perhaps, our favorite hotel in the world. It is unique and historic and unforgettable. We love the fireplace in the room and the heated pool. We stay here every time we visit Antigua, and we love it more each time we stay.
Stayed 3 nights in Jan 2026
Verified

10/10 Excellent

Deborah

Liked: Cleanliness, staff & service, amenities
Stunning property. Beautiful grounds.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Rachel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful property, very clean, staff were wonderful!
Stayed 4 nights in Sep 2025
Verified

8/10 Good

Loretta

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful place to stay and tour. The old monastery is centrally located, historic, and well run hotel. Enjoyed!
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Erika

Liked: Cleanliness, amenities, property conditions & facilities
Casa Santo Domingo was honestly a 10/10. It was amazing super clean, beautiful and so peaceful. Definitely worth the stay!
Stayed 3 nights in Nov 2025
Verified

10/10 Excellent

Susanne

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was amazing and the pool was great! I only went in the hot tub once since there were a bunch of young little kids in it
Stayed 8 nights in Dec 2025
Verified

10/10 Excellent

Gisella

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was perfect and always organize Staff very friendly and very polite.
Stayed 2 nights in Oct 2025