2025 5 Star Hotels in Central West End

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Featured Central West End 5 Star Hotels

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5 out of 5
999 North Second Street St. Louis MO
Fully refundable
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
Fully refundableReserve now, pay when you stay
The Ritz-Carlton, St. Louis
See all 1,723 properties in Central West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.