2026 4 Star Hotels in Downtown

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Featured Downtown 4 Star Hotels

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

4 out of 5
110 Sloan St Clemson SC
Fully refundableReserve now, pay when you stay
The Shepherd Hotel Downtown Clemson
The Abernathy of Clemson

The Abernathy of Clemson

4 out of 5
157 Old Greenville Hwy Clemson SC
The Abernathy of Clemson
Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast

4 out of 5
621 S Mechanic St Pendleton SC
Liberty Hall Bed and Breakfast
Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson

4 out of 5
7008 SC-187 Anderson SC
Lake Hartwell Frank Howard Home Clemson
Belvedere

Belvedere

4 out of 5
302 Alameda Ln Anderson SC
Belvedere
Pendleton

Pendleton

4 out of 5
119 Weaver Way Pendleton SC
Pendleton
See all 1,319 properties in Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.