2025 3 Star Hotels in Otay Mesa

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Featured Otay Mesa 3 Star Hotels

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
Bay Club Hotel & Marina
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
Fully refundableReserve now, pay when you stay
The DEXTRO Little Italy, BW Premier Collection
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
Handlery Hotel
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 out of 5
800 Bay Marina Dr, National City, CA
Fully refundableReserve now, pay when you stay
Best Western Plus Marina Gateway Hotel
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S, San Diego, CA
Days Inn by Wyndham San Diego Hotel Circle
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
The Dana on Mission Bay
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

3 out of 5
3737 Sports Arena Blvd, San Diego, CA
Wyndham Garden San Diego Near SeaWorld
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway, San Diego, CA
Fully refundableReserve now, pay when you stay
The Sofia Hotel
Comfort Inn Sea World Area

Comfort Inn Sea World Area

3.5 out of 5
3880 Greenwood St, San Diego, CA
Comfort Inn Sea World Area
See all 4,773 properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.